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Artificial intelligence (AI) has been successfully applied in numerous scientific domains. In biomedicine, AI has already shown tremendous potential, e.g. in the interpretation of next-generation sequencing data and in the design of…

Computing in the life sciences has undergone a transformative evolution, from early computational models in the 1950s to the applications of artificial intelligence (AI) and machine learning (ML) seen today. This paper highlights key…

Other Quantitative Biology · Quantitative Biology 2024-06-21 Samuel A. Donkor , Matthew E. Walsh , Alexander J. Titus

By treating data and models as the source code, Foundation Models (FMs) become a new type of software. Mirroring the concept of software crisis, the increasing complexity of FMs making FM crisis a tangible concern in the coming decade,…

Software Engineering · Computer Science 2024-07-12 Dezhi Ran , Mengzhou Wu , Wei Yang , Tao Xie

Large pre-trained models, also known as foundation models (FMs), are trained in a task-agnostic manner on large-scale data and can be adapted to a wide range of downstream tasks by fine-tuning, few-shot, or even zero-shot learning. Despite…

Artificial Intelligence · Computer Science 2023-04-17 Gengchen Mai , Weiming Huang , Jin Sun , Suhang Song , Deepak Mishra , Ninghao Liu , Song Gao , Tianming Liu , Gao Cong , Yingjie Hu , Chris Cundy , Ziyuan Li , Rui Zhu , Ni Lao

Artificial intelligence is humanity's most promising technology because of the remarkable capabilities offered by foundation models. Yet, the same technology brings confusion and consternation: foundation models are poorly understood and…

Artificial Intelligence · Computer Science 2025-07-01 Rishi Bommasani

Foundational models (FMs) have tremendous potential to revolutionize medical imaging. However, their deployment in real-world clinical settings demands extensive ethical considerations. This paper aims to highlight the ethical concerns…

Computers and Society · Computer Science 2024-06-19 Abhijit Das , Debesh Jha , Jasmer Sanjotra , Onkar Susladkar , Suramyaa Sarkar , Ashish Rauniyar , Nikhil Tomar , Vanshali Sharma , Ulas Bagci

Advances in molecular technologies underlie an enormous growth in the size of data sets pertaining to biology and biomedicine. These advances parallel those in the deep learning subfield of machine learning. Components in the differentiable…

Quantitative Methods · Quantitative Biology 2024-06-14 Alex Jihun Lee , Reza Abbasi-Asl

Generative AI technologies, particularly Large Language Models (LLMs), have transformed information management systems but introduced substantial biases that can compromise their effectiveness in informing business decision-making. This…

Computers and Society · Computer Science 2025-02-18 Xiahua Wei , Naveen Kumar , Han Zhang

Foundation models (FMs) have shown remarkable capabilities in generalized intelligence, multimodal understanding, and adaptive learning across a wide range of domains. However, their deployment in harsh or austere environments --…

Networking and Internet Architecture · Computer Science 2025-09-17 Evan Chen , Seyyedali Hosseinalipour , Christopher G. Brinton , David J. Love

As the capabilities of artificial intelligence (AI) continue to expand rapidly, Human-AI (HAI) Collaboration, combining human intellect and AI systems, has become pivotal for advancing problem-solving and decision-making processes. The…

Animal vocalisations and natural soundscapes are fascinating objects of study, and contain valuable evidence about animal behaviours, populations and ecosystems. They are studied in bioacoustics and ecoacoustics, with signal processing and…

Sound · Computer Science 2024-02-01 Dan Stowell

Brain foundation models bring the foundation model paradigm to the field of neuroscience. Like language and image foundation models, they are general-purpose AI systems pretrained on large-scale datasets that adapt readily to downstream…

Computers and Society · Computer Science 2026-02-04 Margot Hanley , Jiunn-Tyng Yeh , Ryan Rodriguez , Jack Pilkington , Nita Farahany

Foundation Models (FMs) have shown impressive performance on various text and image processing tasks. They can generalize across domains and datasets in a zero-shot setting. This could make them suitable for automated quality inspection…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Simon Baeuerle , Pratik Khanna , Nils Friederich , Angelo Jovin Yamachui Sitcheu , Damir Shakirov , Andreas Steimer , Ralf Mikut

Pre-trained Foundation Models (PFMs) have ushered in a paradigm-shift in Artificial Intelligence, due to their ability to learn general-purpose representations that can be readily employed in a wide range of downstream tasks. While PFMs…

Databases · Computer Science 2024-11-13 Pasquale Balsebre , Weiming Huang , Gao Cong , Yi Li

Time series analysis stands as a focal point within the data mining community, serving as a cornerstone for extracting valuable insights crucial to a myriad of real-world applications. Recent advances in Foundation Models (FMs) have…

Machine Learning · Computer Science 2024-06-19 Yuxuan Liang , Haomin Wen , Yuqi Nie , Yushan Jiang , Ming Jin , Dongjin Song , Shirui Pan , Qingsong Wen

Foundational models (FMs), pretrained on extensive datasets using self-supervised techniques, are capable of learning generalized patterns from large amounts of data. This reduces the need for extensive labeled datasets for each new task,…

Machine Learning · Computer Science 2024-06-19 Quan M. Tran , Suong N. Hoang , Lam M. Nguyen , Dzung Phan , Hoang Thanh Lam

The pervasive uncertainty and dynamic nature of real-world environments present significant challenges for the widespread implementation of machine-driven Intelligent Decision-Making (IDM) systems. Consequently, IDM should possess the…

Artificial Intelligence · Computer Science 2023-05-17 Ying Wen , Ziyu Wan , Ming Zhou , Shufang Hou , Zhe Cao , Chenyang Le , Jingxiao Chen , Zheng Tian , Weinan Zhang , Jun Wang

The advent of large language models (LLMs) has catalyzed a transformative shift in artificial intelligence, paving the way for advanced intelligent agents capable of sophisticated reasoning, robust perception, and versatile action across…

Foundation models (FMs) are transforming computational pathology by offering new ways to analyze histopathology images. However, FMs typically require weeks of training on large databases, making their creation a resource-intensive process.…

Image and Video Processing · Electrical Eng. & Systems 2026-01-27 Till Nicke , Daniela Schacherer , Jan Raphael Schäfer , Natalia Artysh , Antje Prasse , André Homeyer , Andrea Schenk , Henning Höfener , Johannes Lotz

Neuroscience and neurotechnology are currently being revolutionized by artificial intelligence (AI) and machine learning. AI is widely used to study and interpret neural signals (analytical applications), assist people with disabilities…

Artificial Intelligence · Computer Science 2022-04-14 MohammadAli Shaeri , Arshia Afzal , Mahsa Shoaran
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