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In this paper a novel computational technique for finite discrete approximation of continuous dynamical systems suitable for a significant class of biochemical dynamical systems is introduced. The method is parameterized in order to affect…

Systems and Control · Computer Science 2011-08-01 Lubos Brim , Jana Fabrikova , Sven Drazan , David Safranek

Chemotaxis is a fundamental mechanism of cells and organisms, which is responsible for attracting microbes to food, embryonic cells into developing tissues, or immune cells to infection sites. Mathematically chemotaxis is described by the…

Analysis of PDEs · Mathematics 2020-09-30 Erika Hausenblas , Debopriya Mukherjee , Thanh Tran

Dirac-delta distributions are often crucial components of the solid-fluid coupling operators in immersed solution methods for fluid-structure interaction (FSI) problems. This is certainly so for methods like the Immersed Boundary Method…

Numerical Analysis · Mathematics 2013-02-06 Luca Heltai , Francesco Costanzo

The Keller-Segel equation, a classical chemotaxis model, and many of its variants have been extensively studied for decades. In this work, we focus on 3D Keller-Segel equation with a quadratic logistic damping term $-\mu \rho^2$ (modeling…

Analysis of PDEs · Mathematics 2025-08-01 Jiaqi Liu , Yixuan Wang , Tao Zhou

We develop numerical methods for reaction-diffusion systems based on the equations of fluctuating hydrodynamics (FHD). While the FHD formulation is formally described by stochastic partial differential equations (SPDEs), it becomes similar…

Fluid Dynamics · Physics 2018-01-17 Changho Kim , Andy Nonaka , John B. Bell , Alejandro L. Garcia , Aleksandar Donev

Fluid-particle systems are highly sensitive to particle morphologies. While many attempts have been made on shape descriptors and coupling schemes, how to simulate the particle-particle and particle-fluid interactions with a balance between…

Computational Engineering, Finance, and Science · Computer Science 2023-02-01 Yifeng Zhao , Pei Zhang , Liang Lei , S. A. Galindo-Torres , Stan Z. Li

Particle-wall interactions play a crucially important role in various applications such as microfluidic devices for cell sorting, particle separation, entire class of hydrodynamic filtration and its derivatives, etc. Yet, accurate…

Fluid Dynamics · Physics 2025-03-18 Aryan Mehboudi , Shrawan Singhal , S. V. Sreenivasan

This paper proposes a second-order accurate numerical scheme for the Patlak-Keller-Segel system with various mobilities for the description of chemotaxis. Formulated in a variational structure, the entropy part is novelly discretized by a…

Numerical Analysis · Mathematics 2024-06-07 Jie Ding , Cheng Wang , Shenggao Zhou

A new class of implicit-explicit (IMEX) methods combined with a p-adaptive mixed finite element formulation is proposed to simulate the diffusion of reacting species. Hierarchical polynomial functions are used to construct an…

We seek to accelerate and increase the size of simulations for fluid-structure interactions (FSI) by using multiple resolutions in the spatial discretization of the equations governing the time evolution of systems displaying two-way…

Fluid Dynamics · Physics 2017-08-02 Wei Hu , Wenxiao Pan , Milad Rakhsha , Qiang Tian , Haiyan Hu , Dan Negrut

We introduce a hybrid method to couple continuous Galerkin finite element methods and high-order finite difference methods in a nonconforming multiblock fashion. The aim is to optimize computational efficiency when complex geometries are…

Numerical Analysis · Mathematics 2021-11-24 Tuan Anh Dao , Ken Mattsson , Murtazo Nazarov

Single-cell organisms and various cell types use a range of motility modes when following a chemical gradient, but it is unclear which mode is best suited for different gradients. Here, we model directional decision-making in chemotactic…

Cell Behavior · Quantitative Biology 2025-05-12 Albert Alonso , Julius B. Kirkegaard , Robert G. Endres

Transport and mixing of gas species are of particular interest in planetary environments, where interactions among multiple species can occur within confined or porous media. In this work, we present a novel Smoothed Particle Hydrodynamics…

Earth and Planetary Astrophysics · Physics 2025-09-09 Luca Maggioni , Matteo Teodori , Gianfranco Magni , Michelangelo Formisano , Maria Cristina De Sanctis , Francesca Altieri

The chemotaxis pathway of the bacterium Rhodobacter sphaeroides has many similarities to the well-studied pathway in Escherichia coli. It exhibits robust adaptation and has several homologues of the latter's chemotaxis proteins. Recent…

Molecular Networks · Quantitative Biology 2012-04-10 Abdullah Hamadeh , Brian Ingalls , Eduardo Sontag

The Cahn-Hilliard equation is a fundamental model for describing phase separation phenomena in binary mixtures. Traditional numerical methods, such as finite difference and finite element methods, often incur substantial computational cost,…

Numerical Analysis · Mathematics 2026-05-26 Yi Liu , Shuting Gu

In this paper we propose a novel thermodynamically compatible finite volume scheme for the numerical solution of the equations of magnetohydrodynamics (MHD) in one and two space dimensions. As shown by Godunov in 1972, the MHD system can be…

Numerical Analysis · Mathematics 2023-01-23 Saray Busto , Michael Dumbser

A finite-difference time-domain (FDTD) modelling of finite-size zero thickness space-time modulated Huygens' metasurfaces based on Generalized Sheet Transition Conditions (GSTCs), is proposed and numerically demonstrated. A typical…

Optics · Physics 2017-01-06 Scott A. Stewart , Tom J. Smy , Shulabh Gupta

We develop and analyze a stochastic genetic interacting particle method (SGIP) for reaction-diffusion-advection (RDA) equations. The SGIP method employs operator splitting to approximate the advection-diffusion and reaction processes,…

Numerical Analysis · Mathematics 2026-01-07 Boyi Hu , Zhongjian Wang , Jack Xin , Zhiwen Zhang

In this work, we propose efficient and accurate numerical algorithms based on Difference Potentials Method for numerical solution of chemotaxis systems and related models in 3D. The developed algorithms handle 3D irregular geometry with the…

Numerical Analysis · Mathematics 2019-02-12 Yekaterina Epshteyn , Qing Xia

Chemotaxis is the process by which cells behave in a way that follows the chemical gradient. Applications to bacteria growth, tissue inflammation, and vascular tumors provide a focus on optimization strategies. Experiments can characterize…

Optimization and Control · Mathematics 2007-07-18 K. Renee Fister , Maeve L. McCarthy
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