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We study numerical methods for dissipative particle dynamics (DPD), which is a system of stochastic differential equations and a popular stochastic momentum-conserving thermostat for simulating complex hydrodynamic behavior at mesoscales.…

Numerical Analysis · Mathematics 2021-06-08 Xiaocheng Shang

Sensitivity analysis of biochemical reactions aims at quantifying the dependence of the reaction dynamics on the reaction rates. The computation of the parameter sensitivities, however, poses many computational challenges when taking…

Molecular Networks · Quantitative Biology 2018-11-07 Vo Hong Thanh , Roberto Zunino , Corrado Priami

Complex biological and physical transport processes are often described through systems of interacting particles. Excluded-volume effects on these transport processes are well studied, however the interplay between volume exclusion and…

Statistical Mechanics · Physics 2018-06-27 Daniel Wilson , Helen Byrne , Maria Bruna

The Keller-Segel equations are widely used for describing chemotaxis in biology. Recently, a new fully discrete scheme for this model was proposed in [46], mass conservation, positivity and energy decay were proved for the proposed scheme,…

Numerical Analysis · Mathematics 2022-12-16 Wenbin Chen , Qianqian Liu , Jie Shen

We consider a parabolic-ODE-parabolic chemotaxis system with radially symmetric initial data in a two-dimensional disk under the $0$-Neumann boundary condition. Although our system shares similar mathematical structures as the Keller--Segel…

Analysis of PDEs · Mathematics 2025-06-18 Yuri Soga

Microscopic dynamics reveal the origin of the bulk rheological response in complex fluids. In model systems particle motion can be tracked, but for industrially relevant samples this is often impossible. Here we adapt differential dynamic…

Soft Condensed Matter · Physics 2022-02-23 James A. Richards , Vincent A. Martinez , Jochen Arlt

In this work we numerically study the diffusive limit of run & tumble kinetic models for cell motion due to chemotaxis by means of asymptotic preserving schemes. It is well-known that the diffusive limit of these models leads to the…

Numerical Analysis · Mathematics 2011-10-18 Jose A. Carrillo , Bokai Yan

Fluid-particle systems are very common in many natural processes and engineering applications. However, accurately and efficiently modelling fluid-particle systems with complex particle shapes is still a challenging task. Here, we present a…

Fluid Dynamics · Physics 2023-03-22 Pei Zhang , Ling Qiu , S. A. Galindo-Torres , Yilin Chen , A. Scheuermann , Ling Li

Chemotaxis plays a significant role in numerous physiological processes. The Keller-Segel equation serves as a mathematical model for simulating the phenomenon of cell population aggregation under chemotaxis, possessing physical properties…

Numerical Analysis · Mathematics 2025-02-24 Mingmei Chen , Kun Wang , Cong Xie

New model equations are derived for dynamics of self-aggregation of finite-size particles. Differences from standard Debye-Huckel and Keller-Segel models are: the mobility of particles depends on the configuration of their neighbors and…

Pattern Formation and Solitons · Physics 2009-11-11 Darryl D. Holm , Vakhtang Putkaradze

We derive general kinetic and hydrodynamic models of chemotactic aggregation that describe certain features of the morphogenesis of biological colonies (like bacteria, amoebae, endothelial cells or social insects). Starting from a…

Biological Physics · Physics 2009-11-13 Pierre-Henri Chavanis , Clement Sire

There are many interesting physical processes which involve the generation of high density plasmas in large volumes. However, when modeling these systems numerically, the large densities and volumes present a significant computational…

Computational Physics · Physics 2007-05-23 A. E. Schulz , A. D. Greenwood , K. L. Cartwright , P. J. Mardahl

In this paper, a novel computational technique for finite discrete approximation of continuous dynamical systems suitable for a significant class of biochemical dynamical systems is introduced. The method is parameterized in order to affect…

Systems and Control · Computer Science 2011-09-09 L. Brim , J. Fabriková , S. Dražan , D. Šafránek

The chemotactic pathway allows bacteria to respond and adapt to environmental changes, by tuning the tumbling and running motions that are due to clockwise and counterclockwise rotations of their flagella. The pathway is tightly regulated…

Molecular Networks · Quantitative Biology 2009-10-09 Daniela Besozzi , Paolo Cazzaniga , Matteo Dugo , Dario Pescini , Giancarlo Mauri

The aim of this article is to present a hybrid finite element/finite difference method which is used for reconstructions of electromagnetic properties within a realistic breast phantom. This is done by studying the mentioned properties'…

Numerical Analysis · Mathematics 2025-03-14 Eric Lindström , Larisa Beilina

This paper presents an extension of the discrete element method using a phase-field formulation to incorporate grain shape and its evolution. The introduction of a phase variable enables an effective representation of grain geometry and…

Materials Science · Physics 2024-04-09 Alexandre Sac-Morane , Manolis Veveakis , Hadrien Rattez

In this work we propose a Hybrid method with Deviational Particles (HDP) for a plasma modeled by the inhomogeneous Vlasov-Poisson-Landau system. We split the distribution into a Maxwellian part evolved by a grid based fluid solver and a…

Numerical Analysis · Mathematics 2016-02-17 Bokai Yan

In this paper, we develop a novel numerical framework, namely the stochastic interacting particle-field method with particle-in-cell acceleration (SIPF-PIC), for the efficient simulation of the three-dimensional (3D) parabolic-parabolic…

Numerical Analysis · Mathematics 2026-02-11 Jingyuan Hu , Zhongjian Wang , Jack Xin , Zhiwen Zhang

Clustering is an essential technique for discovering patterns in data. The steady increase in amount and complexity of data over the years led to improvements and development of new clustering algorithms. However, algorithms that can…

Machine Learning · Statistics 2021-03-03 Shu Wang , Jonathan G. Yabes , Chung-Chou H. Chang

Stochastic models of chemical systems are often analysed by solving the corresponding Fokker-Planck equation which is a drift-diffusion partial differential equation for the probability distribution function. Efficient numerical solution of…

Numerical Analysis · Mathematics 2011-11-10 Simon L. Cotter , Tomas Vejchodsky , Radek Erban