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To describe the cellular self-aggregation phenomenon, some strongly coupled PDEs named as Keller-Segel (KS) and Patlak-Keller-Segel (PKS) systems were proposed in 1970s. Since KS and PKS systems possess relatively simple structures but…

Analysis of PDEs · Mathematics 2023-08-02 Fanze Kong , Chen-Chih Lai , Juncheng Wei

Fluctuating hydrodynamics (FHD) provides a framework for modeling microscopic fluctuations in a manner consistent with statistical mechanics and nonequilibrium thermodynamics. This paper presents an FHD formulation for isothermal reactive…

Fluid Dynamics · Physics 2018-09-05 Changho Kim , Andy Nonaka , John B. Bell , Alejandro L. Garcia , Aleksandar Donev

Collectives of actively-moving particles can spontaneously separate into dilute and dense phases -- a fascinating phenomenon known as motility-induced phase separation (MIPS). MIPS is well-studied for randomly-moving particles with no…

Biological Physics · Physics 2023-01-31 Hongbo Zhao , Andrej Košmrlj , Sujit S. Datta

In this paper, we propose a kinetic model describing the collective motion by chemotaxis of two species in interaction emitting the same chemoattractant. Such model can be seen as a generalisation to several species of the Othmer-Dunbar-Alt…

Analysis of PDEs · Mathematics 2014-04-21 Luís Almeida , Casimir Emako , Nicolas Vauchelet

Non-equilibrium transport of particles embedded in a liquid crystal host can, by cooling through a phase transition, be exploited to create a remarkable variety of structures including shells, foams, and gels. Due to the complexity of the…

The Fokker-Planck equations (FPEs) for stochastic systems driven by additive symmetric $\alpha$-stable noises may not adequately describe the time evolution for the probability densities of solution paths in some practical applications,…

Dynamical Systems · Mathematics 2020-03-11 Yanjie Zhang , Xiao Wang , Qiao Huang , Jinqiao Duan , Tingting Li

A novel numerical formulation for solving fluid-structure interaction (FSI) problems is proposed where the fluid field is spatially discretized using smoothed particle hydrodynamics (SPH) and the structural field using the finite element…

Computational Engineering, Finance, and Science · Computer Science 2021-06-16 Sebastian L. Fuchs , Christoph Meier , Wolfgang A. Wall , Christian J. Cyron

Solving the Fokker-Planck equation for high-dimensional complex turbulent dynamical systems is an important and practical issue. However, most traditional methods suffer from the curse of dimensionality and have difficulties in capturing…

Methodology · Statistics 2017-12-06 Nan Chen , Andrew J. Majda

Affine frequency division multiplexing (AFDM) is a novel modulation technique based on chirp signals that has been recently proposed as an effective solution for highly reliable communications in high-mobility scenarios. In this paper, we…

Signal Processing · Electrical Eng. & Systems 2024-11-18 Yiwei Tao , Miaowen Wen , Yao Ge , Jun Li , Ertugrul Basar , Naofal Al-Dhahir

The goal of this paper is to study the Moderate Deviation Principle (MDP) for a system of stochastic reaction-diffusion equations with a time-scale separation in slow and fast components and small noise in the slow component. Based on weak…

Probability · Mathematics 2022-02-03 Ioannis Gasteratos , Michael Salins , Konstantinos Spiliopoulos

The Finite State Projection (FSP) method approximates the Chemical Master Equation (CME) by restricting the dynamics to a finite subset of the (typically infinite) state space, enabling direct numerical solution with computable error…

Computational Engineering, Finance, and Science · Computer Science 2026-05-26 Aditya Dendukuri , Shivkumar Chandrasekaran , Linda Petzold

Molecular optimization is a crucial aspect of drug discovery, aimed at refining molecular structures to enhance drug efficacy and minimize side effects, ultimately accelerating the overall drug development process. Many molecular…

Biomolecules · Quantitative Biology 2025-05-15 Kun Li , Xiantao Cai , Jia Wu , Shirui Pan , Huiting Xu , Bo Du , Wenbin Hu

Spatial reaction-diffusion models have been employed to describe many emergent phenomena in biological systems. The modelling technique most commonly adopted in the literature implements systems of partial differential equations (PDEs),…

Quantitative Methods · Quantitative Biology 2015-10-05 Christian A. Yates , Mark B. Flegg

One-dimensional non-equilibrium models of particles subjected to a coagulation-diffusion process are important in understanding non-equilibrium dynamics, and fluctuation-dissipation relation. We consider in this paper transport properties…

Statistical Mechanics · Physics 2015-06-18 Jean-Yves Fortin

To advance understanding of cellular metabolism and reduce batch-to-batch variability in cell culture processes, this study introduces a multi-scale hybrid modeling framework designed to simulate and predict the dynamic behavior of CHO cell…

Molecular Networks · Quantitative Biology 2025-11-13 Keqi Wang , Sarah W. Harcum , Wei Xie

A new computational methodology, termed "PeleLM-FDF" is developed and utilized for high fidelity large eddy simulation (LES) of complex turbulent combustion systems. This methodology is constructed via a hybrid scheme combining the Eulerian…

Fluid Dynamics · Physics 2023-01-11 Aidyn Aitzhan , Shervin Sammak , Peyman Givi , Arash G. Nouri

To obtain explicit understanding of the behavior of dynamical systems, geometrical methods and slow-fast analysis have proved to be highly useful. Such methods are standard for smooth dynamical systems, and increasingly used for continuous,…

Quantitative Methods · Quantitative Biology 2023-10-19 Francesco Montefusco , Morten Gram Pedersen

This study presents a finite difference method (FDM) to model the electromagnetic field propagation in eccentric coaxial waveguides filled with lossy uniaxially anisotropic media. The formulation utilizes conformal transformation to map the…

Computational Engineering, Finance, and Science · Computer Science 2025-01-24 Raul O. Ribeiro , Maria A. Martinez , Guilherme S. Rosa , Rafael A. Penchel

This article addresses the research question if and how the finite cell method, an embedded domain finite element method of high order, may be used in the simulation of metal deposition to harvest its computational efficiency. This…

Numerical Analysis · Mathematics 2018-09-26 Ali Özcan , Stefan Kollmannsberger , John N. Jomo , Ernst Rank

In standard hospital blood tests, the traditional process requires doctors to manually isolate leukocytes from microscopic images of patients' blood using microscopes. These isolated leukocytes are then categorized via automatic leukocyte…

Computer Vision and Pattern Recognition · Computer Science 2024-01-11 Yifei Chen , Chenyan Zhang , Ben Chen , Yiyu Huang , Yifei Sun , Changmiao Wang , Xianjun Fu , Yuxing Dai , Feiwei Qin , Yong Peng , Yu Gao
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