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Unsupervised anomaly detection (UAD) in brain imaging is crucial for identifying pathologies without the need for labeled data. However, accurately localizing anomalies remains challenging due to the intricate structure of brain anatomy and…

Image and Video Processing · Electrical Eng. & Systems 2025-08-06 Farzad Beizaee , Sina Hajimiri , Ismail Ben Ayed , Gregory Lodygensky , Christian Desrosiers , Jose Dolz

Neural network-based anomaly detection remains challenging in clinical applications with little or no supervised information and subtle anomalies such as hardly visible brain lesions. Among unsupervised methods, patch-based auto-encoders…

Image and Video Processing · Electrical Eng. & Systems 2023-02-28 Nicolas Pinon , Geoffroy Oudoumanessah , Robin Trombetta , Michel Dojat , Florence Forbes , Carole Lartizien

Interpretation of medical images for diagnosis and treatment of complex disease from high-dimensional and heterogeneous data remains a key challenge in transforming healthcare. In the last few years, both supervised and unsupervised deep…

Image and Video Processing · Electrical Eng. & Systems 2018-12-20 Khalid Raza , Nripendra Kumar Singh

Unsupervised anomaly detection (UAD) aims to detect anomalies without labeled data, a necessity in many machine learning applications where anomalous samples are rare or not available. Most state-of-the-art methods fall into two categories:…

Machine Learning · Computer Science 2025-07-30 Nicolas Pinon , Carole Lartizien

Recent advances in deep learning led to novel generative modeling techniques that achieve unprecedented quality in generated samples and performance in learning complex distributions in imaging data. These new models in medical image…

Computer Vision and Pattern Recognition · Computer Science 2018-06-15 Xiaoran Chen , Nick Pawlowski , Martin Rajchl , Ben Glocker , Ender Konukoglu

Ring artifacts are prevalent in 3D cone-beam computed tomography (CBCT) due to non-ideal responses of X-ray detectors, substantially affecting image quality and diagnostic reliability. Existing state-of-the-art (SOTA) ring artifact…

Image and Video Processing · Electrical Eng. & Systems 2025-11-11 Qing Wu , Hongjiang Wei , Jingyi Yu , Yuyao Zhang

The NASA Lunar Reconnaissance Orbiter (LRO) has returned petabytes of lunar high spatial resolution surface imagery over the past decade, impractical for humans to fully review manually. Here we develop an automated method using a deep…

Earth and Planetary Astrophysics · Physics 2024-03-13 Adam Lesnikowski , Valentin T. Bickel , Daniel Angerhausen

The primary goal of this work is to study the effectiveness of an unsupervised domain adaptation approach for various applications such as binary classification and anomaly detection in the context of Alzheimer's disease (AD) detection for…

Image and Video Processing · Electrical Eng. & Systems 2022-12-27 Pranath Reddy

Detecting out of distribution (OOD) samples is of paramount importance in all Machine Learning applications. Deep generative modeling has emerged as a dominant paradigm to model complex data distributions without labels. However, prior work…

Machine Learning · Computer Science 2021-01-05 Gowthami Somepalli , Yexin Wu , Yogesh Balaji , Bhanukiran Vinzamuri , Soheil Feizi

Anomaly detection and localization without any manual annotations and prior knowledge is a challenging task under the setting of unsupervised learning. The existing works achieve excellent performance in the anomaly detection, but with…

Computer Vision and Pattern Recognition · Computer Science 2024-05-16 Honghui Chen , Pingping Chen , Huan Mao , Mengxi Jiang

Anomaly detection is the process of identifying atypical data samples that significantly deviate from the majority of the dataset. In the realm of clinical screening and diagnosis, detecting abnormalities in medical images holds great…

Computer Vision and Pattern Recognition · Computer Science 2023-10-11 Xianyao Hu , Congming Jin

Anomalies (or outliers) are prevalent in real-world empirical observations and potentially mask important underlying structures. Accurate identification of anomalous samples is crucial for the success of downstream data analysis tasks. To…

Machine Learning · Computer Science 2022-08-25 Ofir Lindenbaum , Yariv Aizenbud , Yuval Kluger

Robustness against noisy imaging is crucial for practical image anomaly detection systems. This study introduces a Robust Anomaly Detection (RAD) dataset with free views, uneven illuminations, and blurry collections to systematically…

Computer Vision and Pattern Recognition · Computer Science 2024-07-23 Yuqi Cheng , Yunkang Cao , Rui Chen , Weiming Shen

Anomaly detection is of great interest in fields where abnormalities need to be identified and corrected (e.g., medicine and finance). Deep learning methods for this task often rely on autoencoder reconstruction error, sometimes in…

Machine Learning · Computer Science 2020-07-28 Alexander Tong , Guy Wolf , Smita Krishnaswamy

Anomaly detection (AD), separating anomalies from normal data, has many applications across domains, from security to healthcare. While most previous works were shown to be effective for cases with fully or partially labeled data, that…

Machine Learning · Computer Science 2022-08-08 Jinsung Yoon , Kihyuk Sohn , Chun-Liang Li , Sercan O. Arik , Chen-Yu Lee , Tomas Pfister

Recent advances in optical coherence tomography such as the development of high speed ultrahigh resolution scanners and corresponding signal processing techniques may reveal new potential biomarkers in retinal diseases. Newly visible…

In recent years, anomaly detection has become an essential field in medical image analysis. Most current anomaly detection methods for medical images are based on image reconstruction. In this work, we propose a novel anomaly detection…

Computer Vision and Pattern Recognition · Computer Science 2023-01-20 Florentin Bieder , Julia Wolleb , Robin Sandkühler , Philippe C. Cattin

In medical imaging, obtaining large amounts of labeled data is often a hurdle, because annotations and pathologies are scarce. Anomaly detection is a method that is capable of detecting unseen abnormal data while only being trained on…

Computer Vision and Pattern Recognition · Computer Science 2022-06-09 Djennifer K. Madzia-Madzou , Hugo J. Kuijf

We propose a novel unsupervised out-of-distribution detection method for medical images based on implicit fields image representations. In our approach, an auto-decoder feed-forward neural network learns the distribution of healthy images…

Image and Video Processing · Electrical Eng. & Systems 2021-06-10 Sergio Naval Marimont , Giacomo Tarroni

The identification and quantification of markers in medical images is critical for diagnosis, prognosis, and disease management. Supervised machine learning enables the detection and exploitation of findings that are known a priori after…

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