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Artificial intelligence is increasingly integrated into radiotherapy workflows, yet such pipelines remain vulnerable to out-of-distribution image data that may introduce unexpected behavior in clinical tasks. Deep learning-based anomaly…

The detection of heterogeneous mental disorders based on brain readouts remains challenging due to the complexity of symptoms and the absence of reliable biomarkers. This paper introduces CAM (Cortical Anomaly Detection through Masked Image…

Image and Video Processing · Electrical Eng. & Systems 2024-02-14 Hao-Chun Yang , Ole Andreassen , Lars Tjelta Westlye , Andre F. Marquand , Christian F. Beckmann , Thomas Wolfers

Time series anomaly detection is important in modern large-scale systems and is applied in a variety of domains to analyze and monitor the operation of diverse systems. Unsupervised approaches have received widespread interest, as they do…

Machine Learning · Computer Science 2025-10-23 Buang Zhang , Tung Kieu , Xiangfei Qiu , Chenjuan Guo , Jilin Hu , Aoying Zhou , Christian S. Jensen , Bin Yang

Reliably detecting anomalies in a given set of images is a task of high practical relevance for visual quality inspection, surveillance, or medical image analysis. Autoencoder neural networks learn to reconstruct normal images, and hence…

Machine Learning · Computer Science 2019-01-21 Laura Beggel , Michael Pfeiffer , Bernd Bischl

In this work, we tackle the problem of Semi-Supervised Anomaly Segmentation (SAS) in Magnetic Resonance Images (MRI) of the brain, which is the task of automatically identifying pathologies in brain images. Our work challenges the…

Image and Video Processing · Electrical Eng. & Systems 2023-09-26 Felix Meissen , Georgios Kaissis , Daniel Rueckert

Anomaly detection in medical imaging is essential for identifying rare pathological conditions, particularly when annotated abnormal samples are limited. We propose a hybrid anomaly detection framework that integrates self-supervised…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Pritam Kar , Gouri Lakshmi S , Saptarshi Bej

The detection and localization of anomalies is one important medical image analysis task. Most commonly, Computer Vision anomaly detection approaches rely on manual annotations that are both time consuming and expensive to obtain.…

Computer Vision and Pattern Recognition · Computer Science 2023-11-14 Sergio Naval Marimont , Giacomo Tarroni

Supervised deep learning techniques show promise in medical image analysis. However, they require comprehensive annotated data sets, which poses challenges, particularly for rare diseases. Consequently, unsupervised anomaly detection (UAD)…

Image and Video Processing · Electrical Eng. & Systems 2024-03-22 Finn Behrendt , Debayan Bhattacharya , Lennart Maack , Julia Krüger , Roland Opfer , Robin Mieling , Alexander Schlaefer

In real-world clinical practice, overlooking unanticipated findings can result in serious consequences. However, supervised learning, which is the foundation for the current success of deep learning, only encourages models to identify…

We propose the Autoencoding Binary Classifiers (ABC), a novel supervised anomaly detector based on the Autoencoder (AE). There are two main approaches in anomaly detection: supervised and unsupervised. The supervised approach accurately…

Machine Learning · Statistics 2019-03-27 Yuki Yamanaka , Tomoharu Iwata , Hiroshi Takahashi , Masanori Yamada , Sekitoshi Kanai

Medical imaging data suffers from the limited availability of annotation because annotating 3D medical data is a time-consuming and expensive task. Moreover, even if the annotation is available, supervised learning-based approaches suffer…

Image and Video Processing · Electrical Eng. & Systems 2020-11-12 Abinav Ravi Venkatakrishnan , Seong Tae Kim , Rami Eisawy , Franz Pfister , Nassir Navab

Magnetic resonance imaging (MRI) is an invaluable tool for clinical and research applications. Yet, variations in scanners and acquisition parameters cause inconsistencies in image contrast, hindering data comparability and reproducibility…

Image and Video Processing · Electrical Eng. & Systems 2025-09-09 Daniel Scholz , Ayhan Can Erdur , Robbie Holland , Viktoria Ehm , Jan C. Peeken , Benedikt Wiestler , Daniel Rueckert

Anomaly detection (AD) is a fundamental research problem in machine learning and computer vision, with practical applications in industrial inspection, video surveillance, and medical diagnosis. In medical imaging, AD is especially vital…

Image and Video Processing · Electrical Eng. & Systems 2024-04-30 Jinan Bao , Hanshi Sun , Hanqiu Deng , Yinsheng He , Zhaoxiang Zhang , Xingyu Li

Medical imaging is key in modern medicine. From magnetic resonance imaging (MRI) to microscopic imaging for blood cell detection, diagnostic medical imaging reveals vital insights into patient health. To predict diseases or provide…

Cryptography and Security · Computer Science 2025-05-26 Anika Hannemann , Arjhun Swaminathan , Ali Burak Ünal , Mete Akgün

Anomaly detection in images plays a significant role for many applications across all industries, such as disease diagnosis in healthcare or quality assurance in manufacturing. Manual inspection of images, when extended over a monotonously…

Computer Vision and Pattern Recognition · Computer Science 2021-07-21 Vincent Wilmet , Sauraj Verma , Tabea Redl , Håkon Sandaker , Zhenning Li

Anomaly detection refers to the task of finding unusual instances that stand out from the normal data. In several applications, these outliers or anomalous instances are of greater interest compared to the normal ones. Specifically in the…

Image and Video Processing · Electrical Eng. & Systems 2020-01-14 Manpreet Singh Minhas , John Zelek

In the recent times, autoencoders, besides being used for compression, have been proven quite useful even for regenerating similar images or help in image denoising. They have also been explored for anomaly detection in a few cases.…

Computer Vision and Pattern Recognition · Computer Science 2018-04-03 Shruti Mittal , Dattaraj Rao

Unsupervised anomaly detection (UAD) learns one-class classifiers exclusively with normal (i.e., healthy) images to detect any abnormal (i.e., unhealthy) samples that do not conform to the expected normal patterns. UAD has two main…

Computer Vision and Pattern Recognition · Computer Science 2021-07-01 Yu Tian , Guansong Pang , Fengbei Liu , Yuanhong chen , Seon Ho Shin , Johan W. Verjans , Rajvinder Singh , Gustavo Carneiro

Unsupervised anomaly detection (UAD) presents a complementary alternative to supervised learning for brain tumor segmentation in magnetic resonance imaging (MRI), particularly when annotated datasets are limited, costly, or inconsistent. In…

Computer Vision and Pattern Recognition · Computer Science 2025-10-20 Gerard Comas-Quiles , Carles Garcia-Cabrera , Julia Dietlmeier , Noel E. O'Connor , Ferran Marques

Autoencoder and its variants have been widely applicated in anomaly detection.The previous work memory-augmented deep autoencoder proposed memorizing normality to detect anomaly, however it neglects the feature discrepancy between different…

Computer Vision and Pattern Recognition · Computer Science 2020-12-22 Yifei Yang , Shibing Xiang , Ruixiang Zhang
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