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In the way towards Industry 4.0, the complexity of the industrial systems increases due to the presence of multiple agents, Cyber-Physical Systems, distributed sensing, and big data introducing unknown dynamics that affect the production…

Signal Processing · Electrical Eng. & Systems 2020-07-09 Jairo Viola , YangQuan Chen

Neural network-based models have found wide use in automatic long-term electrocardiogram (ECG) analysis. However, such black box models are inadequate for analysing physiological signals where credibility and interpretability are crucial.…

Signal Processing · Electrical Eng. & Systems 2023-01-25 Jinbao Zhang , Xuan Zhang , Lei Jiao , Ole-Christoffer Granmo , Yongjun Qian , Fan Pan

Digital twins (DT) have emerged as a transformative technology, enabling real-time monitoring, simulations, and predictive maintenance across various domains, though their Application in the networking domain remains underexplored. This…

Software Engineering · Computer Science 2025-12-01 D. Sree Yashaswinee , Gargie Tambe , Y. Raghu Reddy , Karthik Vaidhyanathan

Digital Twins, virtual replicas of physical systems that enable real-time monitoring, model updates, predictions, and decision-making, present novel avenues for proactive control strategies for autonomous systems. However, achieving…

Systems and Control · Electrical Eng. & Systems 2025-05-08 Yi-Ping Chen , Ying-Kuan Tsai , Vispi Karkaria , Wei Chen

Interest in the application of engineering methods to problems in congenital heart disease has gained increased popularity over the past decade. The use of computational simulation to examine common clinical problems including single…

Medical Physics · Physics 2011-01-20 Irene Vignon Clementel , Alison L. Marsden , Jeffrey A. Feinstein

The availability of digital twins for the cardiovascular system will enable insightful computational tools both for research and clinical practice. This, however, demands robust and well defined models and methods for the different steps…

Computational Engineering, Finance, and Science · Computer Science 2024-11-21 Pau Romero , Abel Pedrós , Rafael Sebastian , Miguel Lozano , Ignacio García-Fernández

Digital Twin technology creates virtual replicas of physical objects, processes, or systems by replicating their properties, data, and behaviors. This advanced technology offers a range of intelligent functionalities, such as modeling,…

Machine Learning · Computer Science 2024-08-26 Sagar Srinivas Sakhinana , Krishna Sai Sudhir Aripirala , Shivam Gupta , Venkataramana Runkana

A Digital Twin (DT) is a simulation of a physical system that provides information to make decisions that add economic, social or commercial value. The behaviour of a physical system changes over time, a DT must therefore be continually…

Machine Learning · Computer Science 2023-01-04 Felipe Montana , Adam Hartwell , Will Jacobs , Visakan Kadirkamanathan , Andrew R Mills , Tom Clark

Radiotherapy continues to become more precise and data dense, with current treatment regimens generating high frequency imaging and dosimetry streams ideally suited for AI driven temporal modeling to characterize how normal tissues evolve…

Computer Vision and Pattern Recognition · Computer Science 2026-02-24 Anvi Sud , Jialu Huang , Gregory R. Hart , Keshav Saxena , John Kim , Lauren Tressel , Jun Deng

A Digital Twin is a virtual system that can fully describe a physical one. It constantly receives data from its counterpart's sensors, consults external sources, and obtains manual inputs from its stakeholders. The DT uses all this…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-01-02 Laura Bragante Corssac , Juliano Araujo Wickboldt

Digital Twins bring several benefits for planning, operation, and maintenance of remote offshore assets. In this work, we explain the digital twin concept and the capability level scale in the context of wind energy. Furthermore, we…

Signal Processing · Electrical Eng. & Systems 2023-04-04 Florian Stadtmann , Henrik Gusdal Wassertheurer , Adil Rasheed

Simulating glucose dynamics in individuals with type 1 diabetes (T1D) is critical for developing personalized treatments and supporting data-driven clinical decisions. Existing models often miss key physiological aspects and are difficult…

Quantitative Methods · Quantitative Biology 2026-04-16 Valentina Roquemen-Echeverri , Taisa Kushner , Peter G. Jacobs , Clara Mosquera-Lopez

Physiologically based pharmacokinetic (PBPK) models provide a mechanistic framework for simulating radiopharmaceutical kinetics and estimating patient-specific absorbed doses (ADs). PBPK models incorporate prior knowledge of patient…

Medical Physics · Physics 2025-10-29 Nouran R. R. Zaid , Deni Hardiansyah , Tahir Yusufaly , Arman Rahmim

Purpose: To introduce a novel deep learning based approach for fast and high-quality dynamic multi-coil MR reconstruction by learning a complementary time-frequency domain network that exploits spatio-temporal correlations simultaneously…

Image and Video Processing · Electrical Eng. & Systems 2021-06-21 Chen Qin , Jinming Duan , Kerstin Hammernik , Jo Schlemper , Thomas Küstner , René Botnar , Claudia Prieto , Anthony N. Price , Joseph V. Hajnal , Daniel Rueckert

Digital twins (DTs) are an emerging capability in additive manufacturing (AM), set to revolutionize design optimization, inspection, in situ monitoring, and root cause analysis. AM DTs typically incorporate multimodal data streams, ranging…

Human-Computer Interaction · Computer Science 2024-05-22 Vuthea Chheang , Saurabh Narain , Garrett Hooten , Robert Cerda , Brian Au , Brian Weston , Brian Giera , Peer-Timo Bremer , Haichao Miao

A human body digital twin (DT) is a virtual representation of an individual's physiological state, created using real-time data from sensors and medical test devices, with the purpose of simulating, predicting, and optimizing health…

Artificial Intelligence · Computer Science 2024-04-24 Chenyu Tang , Wentian Yi , Edoardo Occhipinti , Yanning Dai , Shuo Gao , Luigi G. Occhipinti

A digital twin is a virtual representation that accurately replicates its physical counterpart, fostering bi-directional real-time data exchange throughout the entire process lifecycle. For Laser Directed Energy Deposition of Wire…

Computational Engineering, Finance, and Science · Computer Science 2024-12-05 Maximilian Kannapinn , Fabian Roth , Oliver Weeger

Personalized chronic care requires the integration of multimodal health data to enable precise, adaptive, and preventive decision-making. Yet most current digital twin (DT) applications remain organ-specific or tied to isolated data types,…

Software Engineering · Computer Science 2025-10-13 Amal Elgammal , Bernd J. Krämer , Michael P. Papazoglou , Mira Raheem

Echocardiography is routine for cardiac examination. However, 2D ultrasound (US) struggles with accurate metric calculation and direct observation of 3D cardiac structures. Moreover, 3D US is limited by low resolution, small field of view…

Understanding user identity and behavior is central to applications such as personalization, recommendation, and decision support. Most existing approaches rely on deterministic embeddings or black-box predictive models, offering limited…

Machine Learning · Computer Science 2025-12-23 Daniel David