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Optical resonant microcavities with ultra high quality factors are widely used for biosensing. Until now, the primary method of detection has been based upon tracking the resonant wavelength shift as a function of biodetection events. One…

Fluorescence-guided surgery has emerged as a vital tool for tumour resection procedures. As well as intraoperative tumour visualisation, 5-ALA-induced PpIX provides an avenue for quantitative tumour identification based on ratiometric…

Various optical ultrasound microsensors have been developed with size ranging from tens to hundreds of micrometers. However, it becomes challenging to further minimize these sensors' size. In this work, we proposed a method that use a…

Optics · Physics 2025-12-24 Mengyue Zhang , Changhui Li

This paper presents an improved tactile sensor using a piezoelectric bimorph able to differentiate soft materials with similar mechanical characteristics. The final aim is to develop intelligent surgical tools for brain tumour resection…

Medical Physics · Physics 2018-05-03 David Oliva Uribe , Johan Schoukens , Ralf Stroop

We present the development of SpeCamX, a mobile application that transforms any unmodified smartphone into a powerful multispectral imager capable of capturing multispectral information. Our application includes an augmented…

Image and Video Processing · Electrical Eng. & Systems 2023-03-07 Qinghua He , Wanyu Li , Yaping Shi , Yi Yu , Yi Zhang , Wenqian Geng , Zhiyuan Sun , Ruikang K Wang

Respiratory rate (RR) is a vital sign with significant diagnostic value. Existing RR monitors often suffer from baseline drift over time, breaths can be occluded by limb or body movements, and many systems struggle to resolve shallow or…

Major biological discoveries have been made by interrogating living organisms with light. However, the limited penetration of unscattered photons within biological tissues severely limits the depth range covered by optical methods.…

We describe an easy-to-implement technique that allows for a complete experimental characterization of sub-wavelength diameter tapered optical fibers. Our method is based on a direct and fast numerical analysis of the backward Brillouin…

Liquid phase sensing applications at 1550~nm are highly desirable due to widely available off-the-shelf components. Generally, liquids at 1550~nm induce a high absorption loss that limits the overall sensor's sensitivity and detection…

Optics · Physics 2021-02-10 Ubaid Ullah , M. Imran Cheema

We introduce a design for a tip-tilt sensor with integrated single-mode fiber coupling for use with the front-end prototype of the iLocater spectrograph at the Large Binocular Telescope to detect vibrations that occur within the optical…

The neuroimage analysis community has neglected the automated segmentation of the olfactory bulb (OB) despite its crucial role in olfactory function. The lack of an automatic processing method for the OB can be explained by its challenging…

Computer Vision and Pattern Recognition · Computer Science 2023-08-25 Santiago Estrada , Ran Lu , Kersten Diers , Weiyi Zeng , Philipp Ehses , Tony Stöcker , Monique M. B Breteler , Martin Reuter

The biliary tree is a network of tubes that connects the liver to the gallbladder, an organ right beneath it. The bile duct is the major tube in the biliary tree. The dilatation of a bile duct is a key indicator for more major problems in…

Image and Video Processing · Electrical Eng. & Systems 2022-09-13 Mohammad AL-Oudat , Saleh Alomari , Hazem Qattous , Mohammad Azzeh , Tariq AL-Munaizel

Breast cancer is the leading cause of mortality among women. Inspection of breasts by palpation is the key to early detection. We aim to create a wearable tactile glove that could localize the lump in breasts using deep learning (DL). In…

Pulmonary Tuberculosis (PTB) remains a major challenge for global health, especially in areas with poor medical resources, where access to specialized medical knowledge and diagnostic tools is limited. This paper presents an auxiliary…

Image and Video Processing · Electrical Eng. & Systems 2025-02-24 HaoYu Li

We present a fluorescence-lifetime based method for monitoring cell and tissue activity in situ, during cell culturing and in the presence of a strong autofluorescence background. The miniature fiber-optic probes are easily incorporated in…

Biological Physics · Physics 2014-12-12 Manuel Ryser , Lisa Künzi , Marianne Geiser , Martin Frenz , Jaro Rička

The use of efficient wavelength-shifters from the vacuum-ultraviolet to the photosensor's range of sensitivity is a key feature in detectors for Dark Matter search and neutrino physics based on liquid argon scintillation detection. Thin…

In this paper, we propose a tightly-coupled, multi-modal simultaneous localization and mapping (SLAM) framework, integrating an extensive set of sensors: IMU, cameras, multiple lidars, and Ultra-wideband (UWB) range measurements, hence…

Robotics · Computer Science 2021-10-06 Thien-Minh Nguyen , Shenghai Yuan , Muqing Cao , Thien Hoang Nguyen , Lihua Xie

Researchers have shown significant correlations among segmented objects in various medical imaging modalities and disease related pathologies. Several studies showed that using hand crafted features for disease prediction neglects the…

Image and Video Processing · Electrical Eng. & Systems 2024-01-22 Fahim Ahmed Zaman , Wahidul Alam , Tarun Kanti Roy , Amanda Chang , Kan Liu , Xiaodong Wu

Cell-based biosensors constitute a fundamental tool in biotechnology, and their relevance has greatly increased in recent years as a result of a surging demand for reduced animal testing and for high-throughput and cost-effective in vitro…

The flexible endoscope is a minimally invasive tool in clinical settings, but most of them rely on exogenous staining for diagnosis to provide qualitative information. Here, we demonstrated a flexible endoscopic microscopy (FEM) with…

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