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A low-cost, robust, and simple mechanism to measure hemoglobin would play a critical role in the modern health infrastructure. Consistent sample acquisition has been a long-standing technical hurdle for photometer-based portable hemoglobin…

Medical Physics · Physics 2017-12-04 Chris Wu , Tanay Tandon

Optical fiber sensing carries a number of potential advantages for diagnostics and biomarker detection and monitoring, yet particular challenges persist in linking molecular recognition events to a change in the refractive index. DNA…

Background: Mycobacterium Tuberculosis (TB) is an infectious bacterial disease presenting similar symptoms to pneumonia; therefore, differentiating between TB and pneumonia is challenging. Therefore, the main aim of this study is proposing…

Machine Learning · Computer Science 2020-09-07 Toktam Khatibi , Ali Farahani , Hossein Sarmadian

Tuberculosis remains a critical global health issue, particularly in resource-limited and remote areas. Early detection is vital for treatment, yet the lack of skilled radiologists underscores the need for artificial intelligence…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Neel Patel , Alexander Wong , Ashkan Ebadi

Objective: The automatic discrimination between the coughing sounds produced by patients with tuberculosis (TB) and those produced by patients with other lung ailments. Approach: We present experiments based on a dataset of 1358 forced…

Sound · Computer Science 2022-05-12 Madhurananda Pahar , Marisa Klopper , Byron Reeve , Grant Theron , Rob Warren , Thomas Niesler

Tuberculosis is an infectious disease that is leading to the death of millions of people across the world. The mortality rate of this disease is high in patients suffering from immuno-compromised disorders. The early diagnosis of this…

Image and Video Processing · Electrical Eng. & Systems 2021-08-29 G Jignesh Chowdary , Suganya G , Premalatha M , Karunamurthy K

Tuberculosis (TB), an infectious bacterial disease, is a significant cause of death, especially in low-income countries, with an estimated ten million new cases reported globally in $2020$. While TB is treatable, non-adherence to the…

The sudden rise of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic early 2020 throughout the world has called into drastic action measures to do instant detection and reduce the spread rate. The common diagnostics…

Instrumentation and Detectors · Physics 2024-06-12 Aref Asghari , Chao Wang , Kyoung Min Yoo , Hamed Dalir , Ray T. Chen

We propose a learning method well-suited to infer the presence of Tuberculosis (TB) manifestations on Computer Tomography (CT) scans mimicking the radiologist reports. Latent features are extracted from the CT volumes employing the V-Net…

Image and Video Processing · Electrical Eng. & Systems 2019-07-30 Pedro M. Gordaliza , Juan José Vaquero , Sally Sharpe , Fergus Gleeson , Arrate Muñoz-Barrutia

Tuberculosis persists as a global health crisis, especially in resource-limited populations and remote regions, with more than 10 million individuals newly infected annually. It stands as a stark symbol of inequity in public health.…

Image and Video Processing · Electrical Eng. & Systems 2025-03-12 Neel Patel , Alexander Wong , Ashkan Ebadi

Wireless and wearable ultrasound devices promise to enable continuous ultrasound monitoring, but power consumption and data throughput remain critical challenges. Reducing the number of transmit events per second directly impacts both. We…

Image and Video Processing · Electrical Eng. & Systems 2026-01-29 Oisín Nolan , Wessel L. van Nierop , Louis D. van Harten , Tristan S. W. Stevens , Ruud J. G. van Sloun

Crohn's disease and intestinal tuberculosis share many overlapping features such as clinical, radiological, endoscopic, and histological features - particularly granulomas, making it challenging to clinically differentiate them. Our…

Image and Video Processing · Electrical Eng. & Systems 2025-03-04 Shashwat Gupta , Sarthak Gupta , Akshan Agrawal , Mahim Naaz , Rajanikanth Yadav , Priyanka Bagade

We demonstrate novel instrumentation for spontaneous Raman spectroscopy in biofluids, enabling development of a portable, automated, reliable diagnostics technique requiring minimal operator expertise to quantify disease markers. Label-free…

Biological Physics · Physics 2021-05-27 Emily E. Storey , Duxuan Wu , Amr S. Helmy

Traditional microbial detection methods often rely on the overall property of microbial cultures and cannot resolve individual growth event at high spatiotemporal resolution. As a result, they require bacteria to grow to confluence and then…

Deep learning (DL) has drawn tremendous attention in object localization and recognition for both natural and medical images. U-Net segmentation models have demonstrated superior performance compared to conventional handcrafted…

Computer Vision and Pattern Recognition · Computer Science 2021-03-29 Sivaramakrishnan Rajaraman , Les Folio , Jane Dimperio , Philip Alderson , Sameer Antani

Tuberculosis (TB) is a infectious global health challenge. Chest X-rays are a standard method for TB screening, yet many countries face a critical shortage of radiologists capable of interpreting these images. Machine learning offers an…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Denis Musinguzi , Andrew Katumba , Sudi Murindanyi

In this paper we present a label-free, stable and highly sensitive fiber-optic sensor for detection of environmental toxin microcystin-LR (MC-LR). Thiolated MC-LR-targeting aptamer covalently immobilized on dual-resonance long-period fiber…

The evaluation of infectious disease processes on radiologic images is an important and challenging task in medical image analysis. Pulmonary infections can often be best imaged and evaluated through computed tomography (CT) scans, which…

Image and Video Processing · Electrical Eng. & Systems 2021-09-24 Ashia Lewis , Evanjelin Mahmoodi , Yuyue Zhou , Megan Coffee , Elena Sizikova

Tuberculosis (TB) is still considered a leading cause of death and a substantial threat to global child health. Both TB infection and disease are curable using antibiotics. However, most children who die of TB are never diagnosed or…

Detection of small cancer biomarkers with low molecular weight and a low concentration range has always been challenging yet urgent in many clinical applications such as diagnosing early-stage cancer, monitoring treatment and detecting…