Related papers: Lipoarabinomannan-based Tuberculosis Diagnosis usi…
The common techniques to study protein-protein proximity in vivo are not well-adapted to the capabilities and the expertise of a standard proteomics laboratory, typically based on the use of mass spectrometry. With the aim of closing this…
Tuberculosis (TB) is caused by the bacterium Mycobacterium tuberculosis, primarily affecting the lungs. Early detection is crucial for improving treatment effectiveness and reducing transmission risk. Artificial intelligence (AI),…
Monitoring plant health increasingly relies on leaf-mounted sensors that provide real-time physiological data, yet efficiently locating and sampling these sensors in complex agricultural environments remains a major challenge. We present an…
The achievement of all-fibre functional nano-modules for subcellular label-free measurement has long been pursued due to the limitations of manufacturing techniques. In this paper, a compact all-fibre label-free nano-sensor composed of a…
Continuous ambulatory monitoring of peripheral vascular perfusion could enable earlier detection of vascular dysfunction in individuals with diabetes mellitus and more timely management of cardiovascular disease. Clinical imaging modalities…
Retinoblastoma is the most prominent childhood primary intraocular malignancy that impacts the vision of children and adults worldwide. In contrasting and comparing with adults it is uveal melanoma. It is an aggressive tumor that can fill…
Although deep learning algorithms have been intensively developed for computer-aided tuberculosis diagnosis (CTD), they mainly depend on carefully annotated datasets, leading to much time and resource consumption. Weakly supervised learning…
Objective The concentration of bilirubin in blood or serum is useful for assessing liver function as well as monitoring treatment. This study evaluates the clinical performance of a novel point-of-care (PoC) device for the detection of…
Type 2 Diabetes Mellitus (T2DM) is a chronic metabolic disease that affects millions of people worldwide. Early detection is crucial as it can alter pancreas function through morphological changes and increased deposition of ectopic fat,…
A key enabling technology for many liquid noble gas (LNG) detectors is the use of the common wavelength shifting medium tetraphenyl butadiene (TPB). TPB thin films are used to shift ultraviolet scintillation light into the visible spectrum…
Tuberculosis (TB) is a top-10 cause of death worldwide. Though the WHO recommends chest radiographs (CXRs) for TB screening, the limited availability of CXR interpretation is a barrier. We trained a deep learning system (DLS) to detect…
Tuberculosis (TB) is one of the world's deadliest infectious diseases, and in South Africa, it contributes a significant burden to the country's health care system. This paper presents an experimental study on the development of a…
Biomarker detection is the key to identifying health risks. However, designing sensitive biosensors in a single-use mode for disease diagnosis remains a major challenge. Here, we report sub-monolayer biolasers with remarkable repeatability…
Glaucoma is a complex group of eye diseases marked by optic nerve damage, commonly linked to elevated intraocular pressure and biomarkers like retinal nerve fiber layer thickness. Understanding how these biomarkers interact is crucial for…
Ultrasound localization microscopy (ULM) enables microvascular imaging at spatial resolutions beyond the acoustic diffraction limit, offering significant clinical potentials. However, ULM performance relies heavily on microbubble (MB)…
Tuberculosis (TB) remains one of the leading causes of mortality worldwide, particularly in resource-limited countries. Chest X-ray (CXR) imaging serves as an accessible and cost-effective diagnostic tool but requires expert interpretation,…
The possible disruption of a microtubule during mitosis can control the duplication of a cancer cell. Cancer detection and treatment may be possible based on the detection and control of microtubule mechanical oscillations in cells through…
Aflatoxin M1 (AFM1) is a carcinogenic compound commonly found in milk in excess of the WHO permissible limit, especially in developing countries. Currently, state-of-the-art tests for detecting AFM1 in milk include chromatographic systems…
Bacterial biofilms underlie many persistent infections, posing major hurdles in antibiotic treatment. Here, we design and demonstrate tug-of-war optical tweezers that can facilitate assessment of cell-cell adhesion - a key contributing…
Contrast-enhanced magnetic resonance imaging (CE-MRI) plays a crucial role in brain tumor assessment; however, its acquisition requires gadolinium-based contrast agents (GBCAs), which increase costs and raise safety concerns. Consequently,…