Related papers: First ClearMind gamma detector prototype for TOF-P…

The aim of this study was to optimize the design of a monolithic LGSO scintillation crystal and micro parallel-hole collimator for the development of a small-animal single photon emission computed tomography (SPECT) system with compact…

Improving the coincidence time resolution (CTR) of time-of-flight positron emission tomography (TOF-PET) systems to achieve a higher signal-to-noise ratio (SNR) gain or even direct positron emission imaging (dPEI) is of paramount importance…

We study the potential of the MCP-PMT read-out to detect single photo-electron using transmission lines. Such a solution limits the number of read-out channels, has a uniform time resolution across the PMT surface and provides…

Accurate Time-of-Flight (TOF) measurement with sub-100 picosecond resolution is a critical requirement for particle identification in future high-energy physics experiments, such as the Belle II $K_{L}$ and Muon (KLM) detector upgrade.…

Intraoperative Gamma Probe (IPG) remains the current gold standard modality for sentinel lymph node identification and tumor removal in cancer patients. However, even alongside the optical dyes they do not meet with <5% false negative rates…

Modern PET systems reach a spatial resolution of 3-10 mm. A disadvantage of this technique is the diffusion of the positron before its decay with a typical range of ca. 1 mm (depending on its energy). This motion and Compton scattering of…

A systematic study is conducted to understand the coincident resolving time (CRT) for a pair of Lutetium-yttrium oxyorthosilicate (LYSO) and the plastic scintillation detector bars under the Geant4 framework. Crystals are coupled to a…

The $\upmu$RWELL-PICOSEC detector, which combines a $\upmu$RWELL gaseous amplification structure with a Cherenkov radiator and photocathode, is a novel approach to acheive fast and precise timing in gaseous detectors. With timing precision…

Background: Total-Body imaging offers high sensitivity, single-bed position, and low dose, but high construction costs limit worldwide utilization. This study compares existing and developing tomographs using plastic scintillators via…

We developed a novel gamma-ray detection system (TIARA) for range monitoring in Particle Therapy. The system employs Cherenkov-based gamma-ray detection modules arranged around the target or patient, operated in time coincidence with a fast…

Plasma profiling time of flight mass spectrometry (PP-TOFMS) has recently gained interest, as it enables the elemental profiling of semiconductor structures with high depth resolution in short acquisition times. As recently shown by Tempez…

Bismuth germanate (BGO) is gaining renewed attention as a viable material for hybrid Cherenkov/scintillation time-of-flight positron emission tomography (TOF-PET) detectors. While single-crystal studies have demonstrated excellent timing…

We present simulations of whole-body low-dose time-of-flight positron emission tomography (TOF-PET) based on the direct surface production [1] by 511 keV gamma rays of energetic electrons via the Photo-electric and Compton Effects,…

The PICOSEC detection concept consists in a "two-stage" Micromegas detector coupled to a Cherenkov radiator and equipped with a photocathode. A proof of concept has already been tested: a single-photoelectron response of 76 ps has been…

We recently proposed a new approach for the real-time monitoring of particle therapy treatments with the goal of achieving high sensitivities on the particle range measurement already at limited counting statistics. This method extends the…

Positron emission tomography (PET) is the most sensitive biomedical imaging modality for non-invasively detecting and visualizing positron-emitting radiopharmaceuticals within a subject. In PET, measuring the time-of-flight (TOF)…

The concept and subsequent experimental verification of the proportionality between pulse amplitude and detector transit time for microchannel plate detectors is presented. This discovery has led to considerable improvement in the overall…

We report a study of the original image reconstruction algorithm based on the time-of-flight maximum likelihood expectation maximisation (TOF MLEM), developed for the total-body (TB) Jagiellonian PET (J-PET) scanners. The method is…

The Multigap Resistive Plate Chambers (MRPCs) provide excellent timing as well as position resolutions at relatively low cost. Therefore, they can be used in medical imaging applications such as PET where precise timing is a crucial…

Monte Carlo simulation plays an important role in the study of time of flight (TOF) positron emission tomography (PET) prototype. As it can incorporate accurate physical modeling of scintillation detection process, from scintillation light…