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In recent years, protein-text models have gained significant attention for their potential in protein generation and understanding. Current approaches focus on integrating protein-related knowledge into large language models through…

Computation and Language · Computer Science 2025-11-11 Juntong Wu , Zijing Liu , He Cao , Hao Li , Bin Feng , Zishan Shu , Ke Yu , Li Yuan , Yu Li

The field of natural language understanding has experienced exponential progress in the last few years, with impressive results in several tasks. This success has motivated researchers to study the underlying knowledge encoded by these…

Artificial Intelligence · Computer Science 2021-06-03 Carlos Aspillaga , Marcelo Mendoza , Alvaro Soto

In recent years, there has been growing interest in leveraging the impressive generalization capabilities and reasoning ability of large language models (LLMs) to improve the performance of recommenders. With this operation, recommenders…

Information Retrieval · Computer Science 2025-08-12 Guanchen Wang , Mingming Ha , Tianbao Ma , Linxun Chen , Zhaojie Liu , Guorui Zhou , Kun Gai

Modern Protein Language Models (PLMs) apply transformer-based model architectures from natural language processing to biological sequences, predicting a variety of protein functions and properties. However, protein language has key…

Machine Learning · Computer Science 2026-02-25 Anna Hart , Chi Han , Jeonghwan Kim , Huimin Zhao , Heng Ji

We demonstrate the complementary natures of neural knowledge graph embedding, fine-grain entity type prediction, and neural language modeling. We show that a language model-inspired knowledge graph embedding approach yields both improved…

Computation and Language · Computer Science 2020-10-13 Rajat Patel , Francis Ferraro

Proteins play a pivotal role in biological systems. The use of machine learning algorithms for protein classification can assist and even guide biological experiments, offering crucial insights for biotechnological applications. We…

Quantitative Methods · Quantitative Biology 2024-10-24 Yizheng Wang , Yixiao Zhai , Yijie Ding , Quan Zou

Neural machine translation (NMT) offers a novel alternative formulation of translation that is potentially simpler than statistical approaches. However to reach competitive performance, NMT models need to be exceedingly large. In this paper…

Computation and Language · Computer Science 2016-09-23 Yoon Kim , Alexander M. Rush

We propose a segmental neural language model that combines the generalization power of neural networks with the ability to discover word-like units that are latent in unsegmented character sequences. In contrast to previous segmentation…

Computation and Language · Computer Science 2019-06-19 Kazuya Kawakami , Chris Dyer , Phil Blunsom

Although neural models have achieved remarkable performance, they still encounter doubts due to the intransparency. To this end, model prediction explanation is attracting more and more attentions. However, current methods rarely…

Computer Vision and Pattern Recognition · Computer Science 2024-01-30 Yong Guan , Freddy Lecue , Jiaoyan Chen , Ru Li , Jeff Z. Pan

Many multi-domain neural machine translation (NMT) models achieve knowledge transfer by enforcing one encoder to learn shared embedding across domains. However, this design lacks adaptation to individual domains. To overcome this…

Computation and Language · Computer Science 2021-02-15 Haoming Jiang , Chen Liang , Chong Wang , Tuo Zhao

Mechanistic interpretability aims to understand how models store representations by breaking down neural networks into interpretable units. However, the occurrence of polysemantic neurons, or neurons that respond to multiple unrelated…

Computer Vision and Pattern Recognition · Computer Science 2023-04-20 Laura O'Mahony , Vincent Andrearczyk , Henning Muller , Mara Graziani

As large language models (LLMs) are increasingly deployed worldwide, ensuring their fair and comprehensive cultural understanding is important. However, LLMs exhibit cultural bias and limited awareness of underrepresented cultures, while…

Computation and Language · Computer Science 2026-03-31 Taisei Yamamoto , Ryoma Kumon , Danushka Bollegala , Hitomi Yanaka

This paper introduces the Contextual Evaluation Model (CEM), a novel method for knowledge representation and manipulation. The CEM differs from existing models in that it integrates facts, patterns and sequences into a single contextual…

Artificial Intelligence · Computer Science 2019-06-10 Victor E Hansen

Knowledge bases provide applications with the benefit of easily accessible, systematic relational knowledge but often suffer in practice from their incompleteness and lack of knowledge of new entities and relations. Much work has focused on…

Computation and Language · Computer Science 2013-03-19 Danqi Chen , Richard Socher , Christopher D. Manning , Andrew Y. Ng

Pre-trained language models (PLMs) contain vast amounts of factual knowledge, but how the knowledge is stored in the parameters remains unclear. This paper delves into the complex task of understanding how factual knowledge is stored in…

Computation and Language · Computer Science 2023-12-21 Yuheng Chen , Pengfei Cao , Yubo Chen , Kang Liu , Jun Zhao

Although Deep Neural Networks have seen great success in recent years through various changes in overall architectures and optimization strategies, their fundamental underlying design remains largely unchanged. Computational neuroscience on…

Machine Learning · Computer Science 2019-12-17 Paul Bertens , Seong-Whan Lee

Recurrent Neural Networks (RNNs) have achieved remarkable performance on a range of tasks. A key step to further empowering RNN-based approaches is improving their explainability and interpretability. In this work we present MEME: a model…

Machine Learning · Computer Science 2021-04-15 Dmitry Kazhdan , Botty Dimanov , Mateja Jamnik , Pietro Liò

How are the meanings of linguistic expressions related to their use in concrete cognitive tasks? Visual identification tasks show human speakers can exhibit considerable variation in their understanding, representation and verification of…

Computation and Language · Computer Science 2019-04-08 Lewis O'Sullivan , Shane Steinert-Threlkeld

Protein function is inherently linked to its localization within the cell, and fluorescent microscopy data is an indispensable resource for learning representations of proteins. Despite major developments in molecular representation…

Quantitative Methods · Quantitative Biology 2022-05-25 Anastasia Razdaibiedina , Alexander Brechalov

Introduction: The extracellular matrix (ECM) is a networkof proteins and carbohydrates that has a structural and bio-chemical function. The ECM plays an important role in dif-ferentiation, migration and signaling. Several studies…

Quantitative Methods · Quantitative Biology 2022-02-17 Mohamed Ghafoor , Anh Nguyen