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Imaging and hyperspectral data analysis is central to progress across biology, medicine, chemistry, and physics. The core challenge lies in converting high-resolution or high-dimensional datasets into interpretable representations that…

Image and Video Processing · Electrical Eng. & Systems 2025-12-29 Kamyar Barakati , Yu Liu , Utkarsh Pratiush , Boris N. Slautin , Sergei V. Kalinin

Access to astronomical data through archives and VO is essential but does not solve all problems. Availability of appropriate software for analyzing the data is often equally important for the efficiency with which a researcher can publish…

Instrumentation and Methods for Astrophysics · Physics 2010-04-27 P. Grosbol , D. Tody

The acceleration of materials discovery requires digital platforms that go beyond data repositories to embed learning, optimization, and decision-making directly into research workflows. We introduce DataScribe, an AI-native, cloud-based…

Machine Learning · Computer Science 2026-01-14 Divyanshu Singh , Doguhan Sarıtürk , Cameron Lea , Md Shafiqul Islam , Raymundo Arroyave , Vahid Attari

Cloud platforms allow users to execute tasks directly from their web browser and are a key enabling technology not only for commerce but also for computational science. Research software is often developed by scientists with limited…

Astrophysics lies at the crossroads of big datasets (such as the Large Synoptic Survey Telescope and Gaia), open source software to visualize and interpret high dimensional datasets (such as Glue, WorldWide Telescope, and OpenSpace), and…

Background: The human mind is multimodal. Yet most behavioral studies rely on century-old measures such as task accuracy and latency. To create a better understanding of human behavior and brain functionality, we should introduce other…

Machine Learning · Computer Science 2021-11-30 Moein Razavi , Vahid Janfaza , Takashi Yamauchi , Anton Leontyev , Shanle Longmire-Monford , Joseph Orr

Electron ptychography provides new opportunities to resolve atomic structures with deep sub-angstrom spatial resolution and studying electron-beam sensitive materials with high dose efficiency. In practice, obtaining accurate ptychography…

Materials Science · Physics 2022-04-26 Michael C. Cao , Zhen Chen , Yi Jiang , Yimo Han

This dissertation focuses on the development process of scientific software. It presents a methodology that has emerged over time during development of Monte Carlo tools for high energy physics experiments. A short description of the…

Software Engineering · Computer Science 2022-03-23 T. Przedzinski

First-principles computational spectroscopy is a critical tool for interpreting experiment, performing structure refinement, and developing new physical understanding. Systematically setting up input files for different simulation codes and…

Research software refers to software development tools that accelerate discovery and simplifies access to digital infrastructures. However, although research software platforms can be built increasingly more innovative and powerful than…

Software Engineering · Computer Science 2018-12-27 Doug Mulholland , Paulo Alencar , Donald Cowan

We present mrfmsim, an open-source Python package that facilitates the design, simulation, and analysis of magnetic resonance force microscopy (MRFM) experiments. MRFM is a scanning-probe technique that detects magnetic resonance from…

Computational Physics · Physics 2026-03-03 Peter Sun , Corinne E. Isaac , Michael C. Boucher , Eric W. Moore , Zhen Wang , John A. Marohn

The recent advent of autonomous laboratories, coupled with algorithms for high-throughput screening and active learning, promises to accelerate materials discovery and innovation. As these autonomous systems grow in complexity, the demand…

Autofocus is necessary for high-throughput and real-time scanning in microscopic imaging. Traditional methods rely on complex hardware or iterative hill-climbing algorithms. Recent learning-based approaches have demonstrated remarkable…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Yongping Zhai , Xiaoxi Fu , Qiang Su , Jia Hu , Yake Zhang , Yunfeng Zhou , Chaofan Zhang , Xiao Li , Wenxin Wang , Dongdong Wu , Shen Yan

We present a versatile and highly configurable scanning acoustic platform. This platform, comprising of a high frequency transducer, bespoke positioning system and temperature-regulated sample unit, enables the acoustic probing of materials…

Materials Science · Physics 2010-02-24 N G Parker , P V Nelson , M J W Povey

Defects in crystalline materials control the properties of materials, and their characterization focuses our strategies to optimize performance. Electron microscopy has served as the backbone of our understanding of defect structure and…

Materials Science · Physics 2019-03-19 Daniel S. Gianola , T. Ben Britton , Stefan Zaefferer

As spatial and temporal resolutions of scientific instruments improve, the explosion in the volume of data produced is becoming a key challenge. It can be a critical bottleneck for integration between scientific instruments at the edge and…

Instrumentation and Detectors · Physics 2021-11-03 Kazutomo Yoshii , Rajesh Sankaran , Sebastian Strempfer , Maksim Levental , Mike Hammer , Antonino Miceli

Scientific workflows are a cornerstone of modern scientific computing. They are used to describe complex computational applications that require efficient and robust management of large volumes of data, which are typically stored/processed…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-03-03 Rafael Ferreira da Silva , Loïc Pottier , Tainã Coleman , Ewa Deelman , Henri Casanova

Scientific experiments rely on some type of measurements that provides the required data to extract aimed information or conclusions. Data production and analysis are therefore essential components at the heart of any scientific…

Instrumentation and Detectors · Physics 2021-09-01 Wassim Mansour , Rattana Biv , Cyril Ponchut , Raphael Ponsard , Nicolas Janvier , Pablo Fajardo

In research labs, there is often a need to customise software at every step in a given bioinformatics workflow, but traditionally it has been difficult to obtain both a high degree of customisability and good performance.…

Software Engineering · Computer Science 2012-08-23 Gabriel Keeble-Gagnère , Johan Nyström-Persson , Matthew Bellgard , Kenji Mizuguchi

The fusion of rigorous physical laws with flexible data-driven learning represents a new frontier in scientific simulation, yet bridging the gap between physical interpretability and computational efficiency remains a grand challenge. In…

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