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Data augmentations are widely used in training medical image deep learning models to increase the diversity and size of sparse datasets. However, commonly used augmentation techniques can result in loss of clinically relevant information…

Image and Video Processing · Electrical Eng. & Systems 2024-04-18 Adrit Rao , Andrea Fisher , Ken Chang , John Christopher Panagides , Katherine McNamara , Joon-Young Lee , Oliver Aalami

Multiple instance learning is qualified for many pattern recognition tasks with weakly annotated data. The combination of artificial neural network and multiple instance learning offers an end-to-end solution and has been widely utilized.…

Computer Vision and Pattern Recognition · Computer Science 2022-05-30 Jingjun Yi , Beichen Zhou

In this paper, we introduce a unified estimator to analyze various treatment effects in causal inference, including but not limited to the average treatment effect (ATE) and the quantile treatment effect (QTE). The proposed estimator is…

Methodology · Statistics 2025-03-31 Kuan-Hsun Wu , Li-Pang Chen

Multi-instance learning (MIL) deals with tasks where data is represented by a set of bags and each bag is described by a set of instances. Unlike standard supervised learning, only the bag labels are observed whereas the label for each…

Machine Learning · Computer Science 2021-04-27 Weijia Zhang , Jiuyong Li , Lin Liu

Precision mental health requires treatment decisions that account for heterogeneous symptoms reflecting multiple clinical domains. However, existing methods for estimating individualized treatment effects (ITE) rely on a single summary…

Machine Learning · Computer Science 2026-03-31 Yuying Lu , Wenbo Fei , Yuanjia Wang , Molei Liu

Multiple Instance Learning (MIL) is a popular weakly-supervised method for various applications, with a particular interest in histological whole slide image (WSI) classification. Due to the gigapixel resolution of WSI, applications of MIL…

Computer Vision and Pattern Recognition · Computer Science 2025-05-21 Wenhui Zhu , Peijie Qiu , Xiwen Chen , Zhangsihao Yang , Aristeidis Sotiras , Abolfazl Razi , Yalin Wang

We propose plug-in (PI) and double machine learning (DML) estimators of average treatment effect (ATE), average treatment effect on the treated (ATET) and local average treatment effect (LATE) in the multivariate sample selection model with…

Econometrics · Economics 2025-11-18 Sofiia Dolgikh , Bodan Potanin

Machine learning systems have been widely used to make decisions about individuals who may behave strategically to receive favorable outcomes, e.g., they may genuinely improve the true labels or manipulate observable features directly to…

Artificial Intelligence · Computer Science 2024-10-30 Tian Xie , Zhiqun Zuo , Mohammad Mahdi Khalili , Xueru Zhang

Estimation of the Average Treatment Effect (ATE) is often carried out in 2 steps, wherein the first step, the treatment and outcome are modeled, and in the second step the predictions are inserted into the ATE estimator. In the first steps,…

Methodology · Statistics 2023-07-21 Mehdi Rostami , Olli Saarela

While randomized trials may be the gold standard for evaluating the effectiveness of the treatment intervention, in some special circumstances, single-arm clinical trials utilizing external control may be considered. The causal treatment…

Methodology · Statistics 2025-05-26 Huan Wang , Fei Wu , Yeh-Fong Chen

While average treatment effects (ATE) and conditional average treatment effects (CATE) provide valuable population- and subgroup-level summaries, they fail to capture uncertainty at the individual level. For high-stakes decision-making,…

Methodology · Statistics 2026-03-31 Juraj Bodik , Yaxuan Huang , Bin Yu

In computational pathology, random sampling of patches during training of Multiple Instance Learning (MIL) methods is computationally efficient and serves as a regularization strategy. Despite its promising benefits, questions concerning…

Computer Vision and Pattern Recognition · Computer Science 2024-03-11 H. Keshvarikhojasteh , J. P. W. Pluim , M. Veta

Within the field of causal inference, we consider the problem of estimating heterogeneous treatment effects from data. We propose and validate a novel approach for learning feature representations to aid the estimation of the conditional…

Machine Learning · Statistics 2022-06-23 Michael C. Burkhart , Gabriel Ruiz

A new meta-algorithm for estimating the conditional average treatment effects is proposed in the paper. The main idea underlying the algorithm is to consider a new dataset consisting of feature vectors produced by means of concatenation of…

Machine Learning · Statistics 2019-09-10 Lev V. Utkin , Mikhail V. Kots , Viacheslav S. Chukanov

Researchers and practitioners often wish to measure treatment effects in settings where units interact via markets and recommendation systems. In these settings, units are affected by certain shared states, like prices, algorithmic…

Machine Learning · Statistics 2025-04-15 Chris Hays , Manish Raghavan

Due to the rise of privacy concerns, in many practical applications the training data is aggregated before being shared with the learner, in order to protect privacy of users' sensitive responses. In an aggregate learning framework, the…

Machine Learning · Computer Science 2024-01-23 Adel Javanmard , Lin Chen , Vahab Mirrokni , Ashwinkumar Badanidiyuru , Gang Fu

Reliable estimation of treatment effects from observational data is important in many disciplines such as medicine. However, estimation is challenging when unconfoundedness as a standard assumption in the causal inference literature is…

Machine Learning · Computer Science 2024-10-15 Jonas Schweisthal , Dennis Frauen , Maresa Schröder , Konstantin Hess , Niki Kilbertus , Stefan Feuerriegel

Multiple Instance Learning (MIL) is widely used in medical imaging classification to reduce the labeling effort. While only bag labels are available for training, one typically seeks predictions at both bag and instance levels…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Francisco M. Castro-Macías , Pablo Morales-Álvarez , Yunan Wu , Rafael Molina , Aggelos K. Katsaggelos

In recent years, there has been a growing interest in the prediction of individualized treatment effects. While there is a rapidly growing literature on the development of such models, there is little literature on the evaluation of their…

Methodology · Statistics 2023-12-22 J Hoogland , O Efthimiou , TL Nguyen , TPA Debray

Practitioners in medicine, business, political science, and other fields are increasingly aware that decisions should be personalized to each patient, customer, or voter. A given treatment (e.g. a drug or advertisement) should be…

Machine Learning · Statistics 2018-06-15 Alejandro Schuler , Michael Baiocchi , Robert Tibshirani , Nigam Shah