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We present an unsupervised data processing workflow that is specifically designed to obtain a fast conformational clustering of long molecular dynamics simulation trajectories. In this approach we combine two dimensionality reduction…

Chemical Physics · Physics 2023-08-09 Simon Hunkler , Kay Diederichs , Oleksandra Kukharenko , Christine Peter

Packet classification is a vital and complicated task as the processing of packets should be done at a specified line speed. In order to classify a packet as belonging to a particular flow or set of flows, network nodes must perform a…

Networking and Internet Architecture · Computer Science 2014-04-08 Pallavi. V. S , Dr. Rukmani Devi. D

Inside a cell, heterotypic proteins assemble in inhomogeneous, crowded systems where the abundance of these proteins vary with cell types. While some protein complexes form putative structures that can be visualized with imaging, there are…

Biomolecules · Quantitative Biology 2021-09-15 Andrei G. Gasic , Atrayee Sarkar , Margaret S. Cheung

Human physiology and pathology arise from the coordinated interactions of diverse single cells. However, analyzing single cells has been limited by the low sensitivity and throughput of analytical methods. DNA sequencing has recently made…

Quantitative Methods · Quantitative Biology 2020-06-23 Nikolai Slavov

Mass spectrometry (MS) based single-cell proteomics (SCP) explores cellular heterogeneity by focusing on the functional effectors of the cells - proteins. However, extracting meaningful biological information from MS data is far from…

Identification and alignment of three-dimensional folding of proteins may yield useful information about relationships too remote to be detected by conventional methods, such as sequence comparison, and may potentially lead to prediction of…

Quantitative Methods · Quantitative Biology 2017-01-10 Barış Ekim

Deep learning models for medical image segmentation are primarily data-driven. Models trained with more data lead to improved performance and generalizability. However, training is a computationally expensive process because multiple…

Image and Video Processing · Electrical Eng. & Systems 2021-07-13 Vishwesh Nath , Dong Yang , Ali Hatamizadeh , Anas A. Abidin , Andriy Myronenko , Holger Roth , Daguang Xu

Spectral clustering approaches have led to well-accepted algorithms for finding accurate clusters in a given dataset. However, their application to large-scale datasets has been hindered by computational complexity of eigenvalue…

Machine Learning · Computer Science 2016-03-17 Shahzad Bhatti , Carolyn Beck , Angelia Nedic

The use of brain images as markers for diseases or behavioral differences is challenged by the small effects size and the ensuing lack of power, an issue that has incited researchers to rely more systematically on large cohorts. Coupled…

Machine Learning · Statistics 2015-11-17 Bertrand Thirion , Andrés Hoyos-Idrobo , Jonas Kahn , Gael Varoquaux

Density-based clustering algorithms are widely used for discovering clusters in pattern recognition and machine learning since they can deal with non-hyperspherical clusters and are robustness to handle outliers. However, the runtime of…

Machine Learning · Computer Science 2022-07-07 Difei Cheng , Ruihang Xu , Bo Zhang , Ruinan Jin

Decomposition is a proven way to shrink deep networks without changing input-output dimensionality or interface semantics. We bring this idea to hyperdimensional computing (HDC), where footprint cuts usually shrink the feature axis and…

Machine Learning · Computer Science 2026-02-04 Sanggeon Yun , Hyunwoo Oh , Ryozo Masukawa , Mohsen Imani

This paper presents a novel high speed clustering scheme for high dimensional data streams. Data stream clustering has gained importance in different applications, for example, in network monitoring, intrusion detection, and real-time…

Databases · Computer Science 2015-10-13 Irshad Ahmed , Irfan Ahmed , Waseem Shahzad

The current data tends to be more complex than conventional data and need dimension reduction. Dimension reduction is important in cluster analysis and creates a smaller data in volume and has the same analytical results as the original…

Databases · Computer Science 2011-10-18 Rahmat Widia Sembiring , Jasni Mohamad Zain , Abdullah Embong

Ultra-High-Definition (UHD) image restoration is trapped in a scalability crisis: existing models, bound to pixel-wise operations, demand unsustainable computation. While state space models (SSMs) like Mamba promise linear complexity, their…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Chen Wu , Ling Wang , Zhuoran Zheng , Yuning Cui , Zhixiong Yang , Xiangyu Chen , Yue Zhang , Weidong Jiang , Jingyuan Xia

Designing protein-binding proteins with high affinity is critical in biomedical research and biotechnology. Despite recent advancements targeting specific proteins, the ability to create high-affinity binders for arbitrary protein targets…

Machine Learning · Computer Science 2025-11-03 Zhenqiao Song , Tiaoxiao Li , Lei Li , Martin Renqiang Min

Spectral clustering is a popular clustering method. It first maps data into the spectral embedding space and then uses Kmeans to find clusters. However, the two decoupled steps prohibit joint optimization for the optimal solution. In…

Machine Learning · Computer Science 2024-12-17 Wengang Guo , Wei Ye

High-level synthesis (HLS) has received significant attention in recent years, improving programmability for FPGAs. PolyMage is a domain-specific language (DSL) for image processing pipelines that also has a HLS backend to translate the…

Hardware Architecture · Computer Science 2018-12-20 Vinamra Benara , Ziaul Choudhury , Suresh Purini , Uday Bondhugula

Hyperspectral imaging is gathering significant attention due to its potential in various domains such as geology, agriculture, ecology, and surveillance. However, the associated processing algorithms, which are essential for enhancing…

Signal Processing · Electrical Eng. & Systems 2023-10-04 El Mehdi Abdali , Daniele Picone , Mauro Dalla-Mura , Stéphane Mancini

This study introduces a novel unsupervised medical image feature extraction method that employs spatial stratification techniques. An objective function based on weight is proposed to achieve the purpose of fast image recognition. The…

Image and Video Processing · Electrical Eng. & Systems 2024-06-28 Qishi Zhan , Dan Sun , Erdi Gao , Yuhan Ma , Yaxin Liang , Haowei Yang

At the Large Hadron Collider, the vast amount of data from experiments demands not only sophisticated algorithms but also substantial computational power for efficient processing. This paper introduces hardware acceleration as an essential…

High Energy Physics - Experiment · Physics 2025-01-15 Pelayo Leguina López , Santiago Folgueras
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