Related papers: Knot data analysis using multiscale Gauss link int…
The protein-ligand binding affinity (PLA) prediction goal is to predict whether or not the ligand could bind to a protein sequence. Recently, in PLA prediction, deep learning has received much attention. Two steps are involved in deep…
Gland segmentation is a critical step to quantitatively assess the morphology of glands in histopathology image analysis. However, it is challenging to separate densely clustered glands accurately. Existing deep learning-based approaches…
Topological data analysis (TDA) approaches are becoming increasingly popular for studying the dependence patterns in multivariate time series data. In particular, various dependence patterns in brain networks may be linked to specific tasks…
Scientific data has been growing in both size and complexity across the modern physical, engineering, life and social sciences. Spatial structure, for example, is a hallmark of many of the most important real-world complex systems, but its…
The development of machine learning models based on computed tomography (CT) imaging has been a major focus due to the promise that imaging holds for diagnosis, staging, and prognostication. These models often rely on the extraction of…
Understanding how the spatial structure of blood vessel networks relates to their function in healthy and abnormal biological tissues could improve diagnosis and treatment for diseases such as cancer. New imaging techniques can generate…
Quantification and classification of protein structures, such as knotted proteins, often requires noise-free and complete data. Here we develop a mathematical pipeline that systematically analyzes protein structures. We showcase this…
This paper introduces new methodology based on the field of Topological Data Analysis for detecting anomalies in multivariate time series, that aims to detect global changes in the dependency structure between channels. The proposed…
We construct a new invariant of transverse links in the standard contact structure on R^3. This invariant is a doubly filtered version of the knot contact homology differential graded algebra (DGA) of the link. Here the knot contact…
Topological Data Analysis (TDA) is a rapidly growing field, which studies methods for learning underlying topological structures present in complex data representations. TDA methods have found recent success in extracting useful geometric…
Embedding methods have demonstrated robust performance on the task of link prediction in knowledge graphs, by mostly encoding entity relationships. Recent methods propose to enhance the loss function with a literal-aware term. In this…
The widespread enthusiasm for deep learning has recently expanded into the domain of tabular data. Recognizing that the advancement in deep tabular methods is often inspired by classical methods, e.g., integration of nearest neighbors into…
The primary objects of study in the ``knot theory of complex plane curves'' are C-links: links (or knots) cut out of a 3-sphere in the complex plane by complex plane transverse and totally tangential. Transverse C-links are naturally…
This book gives a thorough introduction to topological data analysis (TDA), the application of algebraic topology to data science. Algebraic topology is traditionally a very specialized field of math, and most mathematicians have never been…
Graph Theory and Topological Data Analytics, while powerful, have many drawbacks related to their sensitivity and consistency with TDA & Graph Network Analytics. In this paper, we aim to propose a novel approach for encoding vectorized…
In a novel application of the tools of topological data analysis (TDA) to nonperturbative quantum gravity, we introduce a new class of observables that allows us to assess whether quantum spacetime really resembles a ``quantum foam" near…
Topological Data Analysis (TDA) provides novel approaches that allow us to analyze the geometrical shapes and topological structures of a dataset. As one important application, TDA can be used for data visualization and dimension reduction.…
In practical applications, we often have to deal with high order data, such as a grayscale image and a video sequence are intrinsically 2nd-order tensor and 3rd-order tensor, respectively. For doing clustering or classification of these…
Topological data analysis (TDA), as a relatively recent approach, has demonstrated great potential in capturing the intrinsic and robust structural features of complex data. While persistent homology, as a core tool of TDA, focuses on…
Persistent homology is a widely-used tool in topological data analysis (TDA) for understanding the underlying shape of complex data. By constructing a filtration of simplicial complexes from data points, it captures topological features…