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To turn environmentally derived metabarcoding data into community matrices for ecological analysis, sequences must first be clustered into operational taxonomic units (OTUs). This task is particularly complex for data including large…

Quantitative Methods · Quantitative Biology 2025-02-17 Brendan Furneaux , Sten Anslan , Panu Somervuo , Jenni Hultman , Nerea Abrego , Tomas Roslin , Otso Ovaskainen

Biogeographical regions (bioregions) reveal how different sets of species are spatially grouped and therefore are important units for conservation, historical biogeography, ecology and evolution. Several methods have been developed to…

Quantitative Methods · Quantitative Biology 2016-12-01 Daniel Edler , Thaís Guedes , Alexander Zizka , Martin Rosvall , Alexandre Antonelli

Data is crucial for machine learning (ML) applications, yet acquiring large datasets can be costly and time-consuming, especially in complex, resource-intensive fields like biopharmaceuticals. A key process in this industry is upstream…

Machine Learning · Computer Science 2025-06-23 Johnny Peng , Thanh Tung Khuat , Katarzyna Musial , Bogdan Gabrys

1. Expert knowledge elicitation provides information to characterize ecological systems and management options. Linking expert knowledge elicitation with a curated question catalog supports a community of practice for ongoing improvement of…

Machine- and deep-learning approaches for biological sequences depend critically on transforming raw DNA, RNA, and protein FASTA files into informative numerical representations. However, this process is often fragmented across multiple…

Genomics · Quantitative Biology 2025-12-01 Hamid Ismail , Marwan Bikdash

Microbiology research has access to a very large amount of public information on the habitats of microorganisms. Many areas of microbiology research uses this information, primarily in biodiversity studies. However the habitat information…

Quantitative Methods · Quantitative Biology 2018-11-01 Claire Nédellec , Robert Bossy , Estelle Chaix , Louise Deléger

Biologists study Diatoms, a fundamental algae, to assess the health of aquatic systems. Diatom specimens have traditionally been preserved on analog slides, where a single slide can contain thousands of these microscopic organisms.…

Information Retrieval · Computer Science 2024-11-04 Kio Polson , Marina Potapova , Uttam Meena , Chad Peiper , Joshua Brown , Joshua Agar , Jane Greenberg

In this paper, we present WildlifeDatasets (https://github.com/WildlifeDatasets/wildlife-datasets) - an open-source toolkit intended primarily for ecologists and computer-vision / machine-learning researchers. The WildlifeDatasets is…

Computer Vision and Pattern Recognition · Computer Science 2023-12-15 Vojtěch Čermák , Lukas Picek , Lukáš Adam , Kostas Papafitsoros

High-throughput technologies to collect field data have made observations possible at scale in several branches of life sciences. The data collected can range from the molecular level (genotypes) to physiological (phenotypic traits) and…

Computational Geometry · Computer Science 2021-07-07 Youjia Zhou , Methun Kamruzzaman , Patrick Schnable , Bala Krishnamoorthy , Ananth Kalyanaraman , Bei Wang

The assessment of microbial species biodiversity is essential in ecology and evolutionary biology (Reaka-Kudla et al. 1996), but especially challenging for communities of microorganisms found in the environment (Das et al. 2006, Hillebrand…

Populations and Evolution · Quantitative Biology 2020-11-03 Arianna I. Krinos , Sarah K. Hu , Natalie R. Cohen , Harriet Alexander

The explosion of data throughout the biomedical sciences provides unprecedented opportunities to learn about the dynamics of evolution and disease progression, but harnessing these large and diverse datasets remains challenging. Here, we…

Quantitative Methods · Quantitative Biology 2019-12-03 Sam F. Greenbury , Mauricio Barahona , Iain G. Johnston

With advanced imaging, sequencing, and profiling technologies, multiple omics data become increasingly available and hold promises for many healthcare applications such as cancer diagnosis and treatment. Multimodal learning for integrative…

Genomics · Quantitative Biology 2022-12-20 Sina Tabakhi , Mohammod Naimul Islam Suvon , Pegah Ahadian , Haiping Lu

Metagenomic binning aims to cluster DNA fragments from mixed microbial samples into their respective genomes, a critical step for downstream analyses of microbial communities. Existing methods rely on deterministic representations, such as…

Machine Learning · Computer Science 2025-10-01 Abdulkadir Celikkanat , Andres R. Masegosa , Mads Albertsen , Thomas D. Nielsen

Taxonomic classification in biodiversity research involves organizing biological specimens into structured hierarchies based on evidence, which can come from multiple modalities such as images and genetic information. We investigate whether…

Metagenomics provides a powerful new tool set for investigating evolutionary interactions with the environment. However, an absence of model-based statistical methods means that researchers are often not able to make full use of this…

Quantitative Methods · Quantitative Biology 2013-06-27 John O'Brien , Xavier Didelot , Zamin Iqbal , LucasAmenga-Etego , Bartu Ahiska , Daniel Falush

Motivation: Accurate data analysis and quality control is critical for metagenomic studies. Though many tools exist to analyze metagenomic data there is no consistent framework to integrate and run these tools across projects. Currently,…

Quantitative Methods · Quantitative Biology 2020-09-28 David C Danko , Chris Mason

Increasing interest in the acquisition of biotic and abiotic resources from within the deep sea (e.g. fisheries, oil-gas extraction, and mining) urgently imposes the development of novel monitoring technologies, beyond the traditional…

We introduce a new, simplified model of proteins, which we call protein metastructure. The metastructure of a protein carries information about its secondary structure and $\beta$-strand conformations. Furthermore, protein metastructure…

Biomolecules · Quantitative Biology 2021-11-30 Jørgen Ellegaard Andersen , Hiroyuki Fuji , Yuki Koyanagi

Modern biological research is increasingly data-intensive, leading to a growing demand for effective training in biological data science. In this article, we provide an overview of key resources and best practices available within the…

Metagenomic studies have primarily relied on de novo assembly for reconstructing genes and genomes from microbial mixtures. While reference-guided approaches have been employed in the assembly of single organisms, they have not been used in…