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In-vacuum active pixel detectors enable high sensitivity, highly parallel time- and space-resolved detection of ions from complex surfaces. For the first time, a Timepix detector assembly was combined with a Secondary Ion Mass Spectrometer…
Low voltage transmission electron microscopy (<=80 kV) has many applications in imaging beam-sensitive samples, such as metallic nanoparticles, which may become damaged at higher voltages. To improve resolution, spherical aberration can be…
Imaging systems have traditionally been designed to mimic the human eye and produce visually interpretable measurements. Modern imaging systems, however, process raw measurements computationally before or instead of human viewing. As a…
Label-free optical microscopy through absorption or scattering spectroscopy provides fundamental insights across biology and materials science, yet its sensitivity remains fundamentally limited by photon shot noise. While recent…
Quantum metrology experiments in atomic physics and quantum optics have demonstrated measurement accuracy beyond the shot-noise limit via multi-particle entanglement. At the same time, electron microscopy, an essential tool for…
The rise of nanotechnology has created an ever-increasing need to probe structures on the atomic scale, to which transmission electron microscopy has largely been the answer. Currently, the only way to efficiently thin arbitrary bulk…
Recent advances in photographic sensing technologies have made it possible to achieve light detection in terms of a single photon. Photon counting sensors are being increasingly used in many diverse applications. We address the problem of…
Quantum imaging exploits the spatial correlations between photons to image object features with a higher resolution than a corresponding classical light source could achieve. Using a quantum correlated $N$-photon state, the method of…
Imaging is indispensable for nearly every field of science, engineering, technology, and medicine. However, measurement noise and stochastic distortions pose fundamental limits to accessible spatiotemporal information despite impressive…
We present a novel approach for extracting 3D atomic-level information from transmission electron microscopy (TEM) images affected by significant noise. The approach is based on formulating depth estimation as a semantic segmentation…
Weakly-supervised semantic segmentation (WSSS), which aims to train segmentation models solely using image-level labels, has achieved significant attention. Existing methods primarily focus on generating high-quality pseudo labels using…
Photon-number squeezing and correlations enable measurement of absorption with an accuracy exceeding that of the shot-noise limit. However, sub-shot noise imaging and sensing based on these methods require high detection efficiency, which…
X-ray is a ubiquitous imaging modality in clinical diagnostics and industrial inspections, thanks to its high penetration power. Conventional x-ray imaging system, equipped with energy-integrating detectors, collects approximately 1000 to…
The challenge of imaging low-density objects in an electron microscope without causing beam damage is significant in modern TEM. This is especially true for life science imaging, where the sample, rather than the instrument, still…
Absorption imaging of ultracold atoms is the foundation for quantitative extraction of information from experiments with ultracold atoms. Due to the limited exposure time available in these systems, the signal-to-noise ratio is largest for…
Scanning electron microscopy (SEM), a century-old technique, is today a ubiquitous method of imaging the surface of nanostructures. However, most SEM detectors simply count the number of secondary electrons from a material of interest, and…
A two-level atom cannot emit more than one photon at a time. As early as the 1980s, this quantum feature was identified as a gateway to "single-photon sources", where a regular excitation sequence would create a stream of light particles…
Optical Coherence Tomography (OCT) is an emerging technique in the field of biomedical imaging, with applications in ophthalmology, dermatology, coronary imaging etc. OCT images usually suffer from a granular pattern, called speckle noise,…
We theoretically develop and experimentally demonstrate a holographic method for imaging cold atoms at the diffraction and photon shot noise limits. Aided by a double point source reference field, a simple iterative algorithm robustly…
Atomic force microscopy (AFM) is a well-known tool for studying surface roughness and to collect depth information about features on the top atomic layer of samples. By combining secondary ion mass spectroscopy (SIMS) with focused ion beam…