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Scanning electron microscopy (SEM) is a versatile technique used to image samples at the nanoscale. Conventional imaging by this technique relies on finding the average intensity of the signal generated on a detector by secondary electrons…

Instrumentation and Detectors · Physics 2021-11-04 Akshay Agarwal , John Simonaitis , Vivek K. Goyal , Karl K. Berggren

Focused ion beam (FIB) microscopy suffers from source shot noise - random variation in the number of incident ions in any fixed dwell time - along with random variation in the number of detected secondary electrons per incident ion. This…

Materials Science · Physics 2026-03-12 Minxu Peng , John Murray-Bruce , Karl K. Berggren , Vivek K Goyal

In a focused ion beam (FIB) microscope, source particles interact with a small volume of a sample to generate secondary electrons that are detected, pixel by pixel, to produce a micrograph. Randomness of the number of incident particles…

Medical Physics · Physics 2023-08-15 Minxu Peng , John Murray-Bruce , Vivek K Goyal

Microscope mode imaging for secondary ion mass spectrometry is a technique with the promise of simultaneous high spatial resolution and high speed imaging of biomolecules from complex surfaces. Technological developments such as new…

Instrumentation and Detectors · Physics 2013-09-05 András Kiss , Donald F. Smith , Julia H. Jungmann , Ron M. A. Heeren

Quantum imaging is an advanced method for microscopy or investigating the optical properties of materials or bio-medical inspections with high accuracy, low noise, and extremely low photo-damage. In previous work, we proposed a quantum…

Optics · Physics 2025-05-09 Mousume Samad , Maki Shimizu , Yasuto Hijikata

Particle beam microscopy (PBM) performs nanoscale imaging by pixelwise capture of scalar values representing noisy measurements of the response from secondary electrons (SEs) integrated over a dwell time. Extended to metrology, goals…

Data Analysis, Statistics and Probability · Physics 2023-08-15 Akshay Agarwal , Minxu Peng , Vivek K. Goyal

The independent atom model - pixel counting method (IAM-PCM) for the description of ion-molecule collisions is reviewed. The method was introduced (in 2016) to improve on the simple additivity rule according to which scattering cross…

Atomic Physics · Physics 2025-09-10 Hans Juergen Luedde , Marko Horbatsch , Tom Kirchner

The previously applied independent atom model (IAM) for highly charged ion-molecule collisions which implemented the suppression of multiple ionization and capture on the basis of geometric overlaps of cross-sectional areas representing…

Atomic Physics · Physics 2025-09-15 Hans Jürgen Lüdde , Marko Horbatsch , Tom Kirchner

We demonstrate a prototype of a Focused Ion Beam machine based on the ionization of a laser-cooled cesium beam adapted for imaging and modifying different surfaces in the few-tens nanometer range. Efficient atomic ionization is obtained by…

Mesoscale and Nanoscale Physics · Physics 2016-01-08 M. Viteau , M. Reveillard , L. Kime , B. Rasser , P. Sudraud , Y. Bruneau , G. Khalili , P. Pillet , D. Comparat , I. Guerri , A. Fioretti , D. Ciampini , M. Allegrini , F. Fuso

Modeling artificial scanning electron microscope (SEM) and scanning ion microscope images has recently become important. This is because of the need to provide repeatable images with a priori determined parameters. Modeled artificial images…

Instrumentation and Detectors · Physics 2015-05-19 Petr Cizmar , Andras E. Vladar , Michael T. Postek

Interaction-free measurement (IFM) has been proposed as a means of high-resolution, low-damage imaging of radiation-sensitive samples, such as biomolecules and proteins. The basic setup for IFM is a Mach-Zehnder interferometer, and recent…

Instrumentation and Detectors · Physics 2019-06-12 Akshay Agarwal , Karl K. Berggren , Vivek Goyal

Recovering both amplitude and phase information from a system is a fundamental goal of optical imaging. At the same time, it is crucial to operate at low photon doses to avoid altering the sample, particularly in biological applications.…

Quantum Physics · Physics 2026-01-15 Alberto Paniate , Giuseppe Ortolano , Sarika Soman , Marco Genovese , Ivano Ruo-Berchera

Infrared (IR) imaging is one of the significant tools for the quality control measurements of fabricated samples. Standard IR imaging techniques use direct measurements, where light sources and detectors operate at IR range. Due to the…

Quantum Physics · Physics 2020-09-01 Anna V. Paterova , Hongzhi Yang , Zi S. D. Toa , Leonid A. Krivitsky

Secondary electron (SE) imaging techniques, such as scanning electron microscopy and helium ion microscopy (HIM), use electrons emitted by a sample in response to a focused beam of charged particles incident at a grid of raster scan…

Signal Processing · Electrical Eng. & Systems 2026-03-12 Vaibhav Choudhary , Akshay Agarwal , Vivek K Goyal

Intracavity absorption spectroscopy (ICAS) is a well-established technique for detecting weak absorption signals with ultrahigh sensitivity. Here, we extend this concept to magnetometry using nitrogen-vacancy (NV) centers in diamond. We…

The importance of Image quality assessment (IQA) is ever increasing due to the fast paced advances in imaging technology and computer vision. Among the numerous IQA methods, Structural SIMilarity (SSIM) index and its variants are better…

Image and Video Processing · Electrical Eng. & Systems 2022-12-06 X. Li , W. Armour

Noise is an important factor that degrades the quality of medical images. Impulse noise is a common noise, which is caused by malfunctioning of sensor elements or errors in the transmission of images. In medical images due to presence of…

Computer Vision and Pattern Recognition · Computer Science 2017-10-13 Zohreh HosseinKhani , Mohsen Hajabdollahi , Nader Karimi , Reza Soroushmehr , Shahram Shirani , Kayvan Najarian , Shadrokh Samavi

We demonstrate that a dispersive imaging technique based on the Faraday effect can measure the atom number in a large, ultracold atom cloud with a precision below the atom shot noise level. The minimally destructive character of the…

The principles of quantum optics have yielded a plethora of ideas to surpass the classical limitations of sensitivity and resolution in optical microscopy. While some ideas have been applied in proof-of-principle experiments, imaging a…

Spectral domain optical coherence tomography (OCT) offers high resolution multidimensional imaging, but generally suffers from defocussing, intensity falloff and shot noise, causing artifacts and image degradation along the imaging depth.…

Image and Video Processing · Electrical Eng. & Systems 2021-08-04 Jonathan H. Mason , Yvonne Reinwald , Ying Yang , Sarah Waters , Alicia El Haj , Pierre O. Bagnaninchi
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