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Recent advances in deep learning for medical image segmentation demonstrate expert-level accuracy. However, in clinically realistic environments, such methods have marginal performance due to differences in image domains, including…

Computer Vision and Pattern Recognition · Computer Science 2019-06-13 Ling Zhang , Xiaosong Wang , Dong Yang , Thomas Sanford , Stephanie Harmon , Baris Turkbey , Holger Roth , Andriy Myronenko , Daguang Xu , Ziyue Xu

Histopathological analysis is the present gold standard for precancerous lesion diagnosis. The goal of automated histopathological classification from digital images requires supervised training, which requires a large number of expert…

Image and Video Processing · Electrical Eng. & Systems 2021-11-15 Yuan Xue , Jiarong Ye , Qianying Zhou , Rodney Long , Sameer Antani , Zhiyun Xue , Carl Cornwell , Richard Zaino , Keith Cheng , Xiaolei Huang

While human observers are able to cope with variations in color and appearance of histological stains, digital pathology algorithms commonly require a well-normalized setting to achieve peak performance, especially when a limited amount of…

Computer Vision and Pattern Recognition · Computer Science 2017-08-15 Daniel Bug , Steffen Schneider , Anne Grote , Eva Oswald , Friedrich Feuerhake , Julia Schüler , Dorit Merhof

The success of training deep Convolutional Neural Networks (CNNs) heavily depends on a significant amount of labelled data. Recent research has found that neural style transfer algorithms can apply the artistic style of one image to another…

Computer Vision and Pattern Recognition · Computer Science 2019-09-04 Xu Zheng , Tejo Chalasani , Koustav Ghosal , Sebastian Lutz , Aljosa Smolic

Domain adaptation, a pivotal branch of transfer learning, aims to enhance the performance of machine learning models when deployed in target domains with distinct data distributions. This is particularly critical for object detection tasks,…

Computer Vision and Pattern Recognition · Computer Science 2025-01-07 Helia Mohamadi , Mohammad Ali Keyvanrad , Mohammad Reza Mohammadi

Histopathology can help clinicians make accurate diagnoses, determine disease prognosis, and plan appropriate treatment strategies. As deep learning techniques prove successful in the medical domain, the primary challenges become limited…

Computer Vision and Pattern Recognition · Computer Science 2024-07-11 Zhe Li , Bernhard Kainz

For medical image analysis, segmentation models trained on one or several domains lack generalization ability to unseen domains due to discrepancies between different data acquisition policies. We argue that the degeneration in segmentation…

Computer Vision and Pattern Recognition · Computer Science 2022-08-09 Ziqi Zhou , Lei Qi , Yinghuan Shi

Despite continued advancement in recent years, deep neural networks still rely on large amounts of training data to avoid overfitting. However, labeled training data for real-world applications such as healthcare is limited and difficult to…

Neural networks are prone to overfitting and memorizing data patterns. To avoid over-fitting and enhance their generalization and performance, various methods have been suggested in the literature, including dropout, regularization, label…

Computer Vision and Pattern Recognition · Computer Science 2023-02-08 Humza Naveed , Saeed Anwar , Munawar Hayat , Kashif Javed , Ajmal Mian

Attribute guided face image synthesis aims to manipulate attributes on a face image. Most existing methods for image-to-image translation can either perform a fixed translation between any two image domains using a single attribute or…

Computer Vision and Pattern Recognition · Computer Science 2019-05-02 Behzad Bozorgtabar , Mohammad Saeed Rad , Hazım Kemal Ekenel , Jean-Philippe Thiran

Accurate segmentation of tissue in histopathological images can be very beneficial for defining regions of interest (ROI) for streamline of diagnostic and prognostic tasks. Still, adapting to different domains is essential for…

Image and Video Processing · Electrical Eng. & Systems 2023-03-10 Saul Fuster , Farbod Khoraminia , Trygve Eftestøl , Tahlita C. M. Zuiverloon , Kjersti Engan

Data augmentation is a cornerstone technique in deep learning, widely used to improve model generalization. Traditional methods like random cropping and color jittering, as well as advanced techniques such as CutOut, Mixup, and CutMix, have…

Computer Vision and Pattern Recognition · Computer Science 2025-02-14 Jingyang Li , Jiachun Pan , Kim-Chuan Toh , Pan Zhou

Generalization to previously unseen images with potential domain shifts and different styles is essential for clinically applicable medical image segmentation, and the ability to disentangle domain-specific and domain-invariant features is…

Computer Vision and Pattern Recognition · Computer Science 2022-11-23 Ran Gu , Guotai Wang , Jiangshan Lu , Jingyang Zhang , Wenhui Lei , Yinan Chen , Wenjun Liao , Shichuan Zhang , Kang Li , Dimitris N. Metaxas , Shaoting Zhang

Visual microscopic study of diseased tissue by pathologists has been the cornerstone for cancer diagnosis and prognostication for more than a century. Recently, deep learning methods have made significant advances in the analysis and…

Image and Video Processing · Electrical Eng. & Systems 2022-09-30 Puria Azadi Moghadam , Sanne Van Dalen , Karina C. Martin , Jochen Lennerz , Stephen Yip , Hossein Farahani , Ali Bashashati

Deep neural networks are vulnerable to adversarial examples crafted by applying human-imperceptible perturbations on clean inputs. Although many attack methods can achieve high success rates in the white-box setting, they also exhibit weak…

Computer Vision and Pattern Recognition · Computer Science 2023-08-22 Zhijin Ge , Fanhua Shang , Hongying Liu , Yuanyuan Liu , Liang Wan , Wei Feng , Xiaosen Wang

Histopathology images; microscopy images of stained tissue biopsies contain fundamental prognostic information that forms the foundation of pathological analysis and diagnostic medicine. However, diagnostics from histopathology images…

Computer Vision and Pattern Recognition · Computer Science 2019-10-30 Aïcha BenTaieb , Ghassan Hamarneh

Despite the successes of deep neural networks on many challenging vision tasks, they often fail to generalize to new test domains that are not distributed identically to the training data. The domain adaptation becomes more challenging for…

Computer Vision and Pattern Recognition · Computer Science 2021-03-08 Devavrat Tomar , Manana Lortkipanidze , Guillaume Vray , Behzad Bozorgtabar , Jean-Philippe Thiran

Domain generalization aims to enhance the model robustness against domain shift without accessing the target domain. Since the available source domains for training are limited, recent approaches focus on generating samples of novel…

Computer Vision and Pattern Recognition · Computer Science 2021-08-20 Seogkyu Jeon , Kibeom Hong , Pilhyeon Lee , Jewook Lee , Hyeran Byun

Recently, we have witnessed great progress in the field of medical imaging classification by adopting deep neural networks. However, the recent advanced models still require accessing sufficiently large and representative datasets for…

Computer Vision and Pattern Recognition · Computer Science 2020-10-30 Haoliang Li , YuFei Wang , Renjie Wan , Shiqi Wang , Tie-Qiang Li , Alex C. Kot

Generating realistic synthetic microscopy images is critical for training deep learning models in label-scarce environments, such as cell counting with many cells per image. However, traditional domain adaptation methods often struggle to…

Computer Vision and Pattern Recognition · Computer Science 2025-12-15 Mohammad Dehghanmanshadi , Wallapak Tavanapong