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The rapid growth of digital pathology in recent years has provided an ideal opportunity for the development of artificial intelligence-based tools to improve the accuracy and efficiency of clinical diagnoses. One of the significant…

Image and Video Processing · Electrical Eng. & Systems 2024-03-08 Jack Breen , Kieran Zucker , Katie Allen , Nishant Ravikumar , Nicolas M. Orsi

Domain shift in digital histopathology can occur when different stains or scanners are used, during stain translation, etc. A deep neural network trained on source data may not generalise well to data that has undergone some domain shift.…

Image and Video Processing · Electrical Eng. & Systems 2022-05-10 Zeeshan Nisar , Jelica Vasiljević , Pierre Gançarski , Thomas Lampert

Annotating histopathological images is a time-consuming andlabor-intensive process, which requires broad-certificated pathologistscarefully examining large-scale whole-slide images from cells to tissues.Recent frontiers of transfer learning…

Computer Vision and Pattern Recognition · Computer Science 2020-08-24 Dou Xu , Chang Cai , Chaowei Fang , Bin Kong , Jihua Zhu , Zhongyu Li

Computational histopathology image diagnosis becomes increasingly popular and important, where images are segmented or classified for disease diagnosis by computers. While pathologists do not struggle with color variations in slides,…

Image and Video Processing · Electrical Eng. & Systems 2020-07-27 Hanwen Liang , Konstantinos N. Plataniotis , Xingyu Li

Domain generalization (DG) has been a hot topic in image recognition, with a goal to train a general model that can perform well on unseen domains. Recently, federated learning (FL), an emerging machine learning paradigm to train a global…

Computer Vision and Pattern Recognition · Computer Science 2022-10-04 Junming Chen , Meirui Jiang , Qi Dou , Qifeng Chen

Poor performance of quantitative analysis in histopathological Whole Slide Images (WSI) has been a significant obstacle in clinical practice. Annotating large-scale WSIs manually is a demanding and time-consuming task, unlikely to yield the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-08 Sarah Cechnicka , James Ball , Hadrien Reynaud , Callum Arthurs , Candice Roufosse , Bernhard Kainz

Deep learning models that are trained on histopathological images obtained from a single lab and/or scanner give poor inference performance on images obtained from another scanner/lab with a different staining protocol. In recent years,…

Image and Video Processing · Electrical Eng. & Systems 2020-10-07 Harshal Nishar , Nikhil Chavanke , Nitin Singhal

Data augmentation is a popular pre-processing trick to improve generalization accuracy. It is believed that by processing augmented inputs in tandem with the original ones, the model learns a more robust set of features which are shared…

Machine Learning · Computer Science 2020-07-10 Vihari Piratla , Shiv Shankar

Differences in staining and imaging procedures can cause significant color variations in histopathology images, leading to poor generalization when deploying deep-learning models trained from a different data source. Various color…

Existing domain generalization (DG) methods for cross-person generalization tasks often face challenges in capturing intra- and inter-domain style diversity, resulting in domain gaps with the target domain. In this study, we explore a novel…

Machine Learning · Computer Science 2024-07-02 Junru Zhang , Lang Feng , Zhidan Liu , Yuhan Wu , Yang He , Yabo Dong , Duanqing Xu

Unsupervised domain adaptation methods aim to alleviate performance degradation caused by domain-shift by learning domain-invariant representations. Existing deep domain adaptation methods focus on holistic feature alignment by matching…

Machine Learning · Computer Science 2018-11-20 Jun Wen , Risheng Liu , Nenggan Zheng , Qian Zheng , Zhefeng Gong , Junsong Yuan

The classification of Antibody Mediated Rejection (AMR) in kidney transplant remains challenging even for experienced nephropathologists; this is partly because histological tissue stain analysis is often characterized by low inter-observer…

Computer Vision and Pattern Recognition · Computer Science 2020-07-13 Pietro Antonio Cicalese , Aryan Mobiny , Pengyu Yuan , Jan Becker , Chandra Mohan , Hien Van Nguyen

Federated domain generalization aims to learn a generalizable model from multiple decentralized source domains for deploying on the unseen target domain. The style augmentation methods have achieved great progress on domain generalization.…

Computer Vision and Pattern Recognition · Computer Science 2025-06-05 Yikang Wei

In digital pathology, different staining procedures and scanners cause substantial color variations in whole-slide images (WSIs), especially across different laboratories. These color shifts result in a poor generalization of deep…

Image and Video Processing · Electrical Eng. & Systems 2021-07-27 Sophia J. Wagner , Nadieh Khalili , Raghav Sharma , Melanie Boxberg , Carsten Marr , Walter de Back , Tingying Peng

Deep learning (DL)-based models have demonstrated good performance in medical image segmentation. However, the models trained on a known dataset often fail when performed on an unseen dataset collected from different centers, vendors and…

Computer Vision and Pattern Recognition · Computer Science 2020-09-04 Lei Li , Veronika A. Zimmer , Wangbin Ding , Fuping Wu , Liqin Huang , Julia A. Schnabel , Xiahai Zhuang

Image data augmentation constitutes a critical methodology in modern computer vision tasks, since it can facilitate towards enhancing the diversity and quality of training datasets; thereby, improving the performance and robustness of…

Computer Vision and Pattern Recognition · Computer Science 2025-01-13 Panagiotis Alimisis , Ioannis Mademlis , Panagiotis Radoglou-Grammatikis , Panagiotis Sarigiannidis , Georgios Th. Papadopoulos

The deep learning technique has been shown to be effectively addressed several image analysis tasks in the computer-aided diagnosis scheme for mammography. The training of an efficacious deep learning model requires large data with diverse…

Computer Vision and Pattern Recognition · Computer Science 2023-09-08 Zheren Li , Zhiming Cui , Lichi Zhang , Sheng Wang , Chenjin Lei , Xi Ouyang , Dongdong Chen , Xiangyu Zhao , Yajia Gu , Zaiyi Liu , Chunling Liu , Dinggang Shen , Jie-Zhi Cheng

In this paper, we address domain shifts in pathological images by focusing on shifts within whole slide images~(WSIs), such as patient characteristics and tissue thickness, rather than shifts between hospitals. Traditional approaches rely…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Yuki Shigeyasu , Shota Harada , Akihiko Yoshizawa , Kazuhiro Terada , Naoki Nakazima , Mariyo Kurata , Hiroyuki Abe , Tetsuo Ushiku , Ryoma Bise

A common strategy for improving model robustness is through data augmentations. Data augmentations encourage models to learn desired invariances, such as invariance to horizontal flipping or small changes in color. Recent work has shown…

Computer Vision and Pattern Recognition · Computer Science 2021-05-28 Hubert Lin , Mitchell van Zuijlen , Sylvia C. Pont , Maarten W. A. Wijntjes , Kavita Bala

Multimodal and multi-domain stylization are two important problems in the field of image style transfer. Currently, there are few methods that can perform both multimodal and multi-domain stylization simultaneously. In this paper, we…

Computer Vision and Pattern Recognition · Computer Science 2020-06-03 Minxuan Lin , Fan Tang , Weiming Dong , Xiao Li , Chongyang Ma , Changsheng Xu