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The density of mitotic figures within tumor tissue is known to be highly correlated with tumor proliferation and thus is an important marker in tumor grading. Recognition of mitotic figures by pathologists is known to be subject to a strong…

Domain adaption (DA) and domain generalization (DG) are two closely related methods which are both concerned with the task of assigning labels to an unlabeled data set. The only dissimilarity between these approaches is that DA can access…

Computer Vision and Pattern Recognition · Computer Science 2018-12-27 Mohammad Mahfujur Rahman , Clinton Fookes , Mahsa Baktashmotlagh , Sridha Sridharan

Deep learning (DL) has become one of the mainstream and effective methods for point cloud analysis tasks such as detection, segmentation and classification. To reduce overfitting during training DL models and improve model performance…

Computer Vision and Pattern Recognition · Computer Science 2024-04-30 Qinfeng Zhu , Lei Fan , Ningxin Weng

Domain generalization (DG) aims to learn a model on several source domains, hoping that the model can generalize well to unseen target domains. The distribution shift between domains contains the covariate shift and conditional shift, both…

Computer Vision and Pattern Recognition · Computer Science 2022-09-20 Jianxin Lin , Yongqiang Tang , Junping Wang , Wensheng Zhang

Foundation models have revolutionized the paradigm of digital pathology, as they leverage general-purpose features to emulate real-world pathological practices, enabling the quantitative analysis of critical histological patterns and the…

Detectors often suffer from performance drop due to domain gap between training and testing data. Recent methods explore diffusion models applied to domain generalization (DG) and adaptation (DA) tasks, but still struggle with large…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Boyong He , Yuxiang Ji , Zhuoyue Tan , Liaoni Wu

Domain shift, caused by variations in imaging modalities and acquisition protocols, limits model generalization in medical image segmentation. While foundation models (FMs) trained on diverse large-scale data hold promise for zero-shot…

Computer Vision and Pattern Recognition · Computer Science 2025-04-01 Soumitri Chattopadhyay , Basar Demir , Marc Niethammer

Domain Generalization (DG) is a challenging task in machine learning that requires a coherent ability to comprehend shifts across various domains through extraction of domain-invariant features. DG performance is typically evaluated by…

Computer Vision and Pattern Recognition · Computer Science 2024-05-28 Yiran Luo , Joshua Feinglass , Tejas Gokhale , Kuan-Cheng Lee , Chitta Baral , Yezhou Yang

Domain Generalization (DG) is a fundamental challenge for machine learning models, which aims to improve model generalization on various domains. Previous methods focus on generating domain invariant features from various source domains.…

Computer Vision and Pattern Recognition · Computer Science 2023-09-22 Daoan Zhang , Mingkai Chen , Chenming Li , Lingyun Huang , Jianguo Zhang

Deep neural networks (DNN) have demonstrated unprecedented success for medical imaging applications. However, due to the issue of limited dataset availability and the strict legal and ethical requirements for patient privacy protection, the…

Machine Learning · Computer Science 2023-09-19 Chris Xing Tian , Haoliang Li , Yufei Wang , Shiqi Wang

Deep learning-based medical image segmentation faces significant challenges arising from limited labeled data and domain shifts. While prior approaches have primarily addressed these issues independently, their simultaneous occurrence is…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Zanting Ye , Ke Wang , Wenbing Lv , Qianjin Feng , Lijun Lu

Deep Learning (DL) approaches have been providing state-of-the-art performance in different modalities in the field of medical imagining including Digital Pathology Image Analysis (DPIA). Out of many different DL approaches, Deep…

Computer Vision and Pattern Recognition · Computer Science 2019-04-22 Md Zahangir Alom , Theus Aspiras , Tarek M. Taha , Vijayan K. Asari , TJ Bowen , Dave Billiter , Simon Arkell

The histological assessment of human tissue has emerged as the key challenge for detection and treatment of cancer. A plethora of different data sources ranging from tissue microarray data to gene expression, proteomics or metabolomics data…

Computer Vision and Pattern Recognition · Computer Science 2016-01-05 Thomas J. Fuchs , Joachim M. Buhmann

Domain generalization is critical in computational pathology (CPath) due to inherent domain shifts caused by variations in staining protocols, scanner devices, and imaging settings across clinical centers. Vision-language models (VLMs),…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Amir Mohammad Ezzati , Alireza Malekhosseini , Armin Khosravi , Mohammad Hossein Rohban

Although recent years have witnessed the great success of convolutional neural networks (CNNs) in medical image segmentation, the domain shift issue caused by the highly variable image quality of medical images hinders the deployment of…

Computer Vision and Pattern Recognition · Computer Science 2023-06-01 Ziyang Chen , Yongsheng Pan , Yiwen Ye , Hengfei Cui , Yong Xia

Skin cancer is a serious and potentially fatal disease caused by DNA damage. Early detection significantly increases survival rates, making accurate diagnosis crucial. In this groundbreaking study, we present a hybrid framework based on…

Image and Video Processing · Electrical Eng. & Systems 2025-03-26 Maksuda Akter , Rabea Khatun , Md. Alamin Talukder , Md. Manowarul Islam , Md. Ashraf Uddin

The computer-aided detection (CADe) systems are developed to assist pathologists in slide assessment, increasing diagnosis efficiency and reducing missing inspections. Many studies have shown such a CADe system with deep learning approaches…

Computer Vision and Pattern Recognition · Computer Science 2019-03-05 Wei-Wen Hsu , Chung-Hao Chen , Chang Hoa , Yu-Ling Hou , Xiang Gao , Yun Shao , Xueli Zhang , Jingjing Wang , Tao He , Yanghong Tai

The emergence of digital pathology has opened new horizons for histopathology and cytology. Artificial-intelligence algorithms are able to operate on digitized slides to assist pathologists with diagnostic tasks. Whereas machine learning…

Fully supervised deep models have shown promising performance for many medical segmentation tasks. Still, the deployment of these tools in clinics is limited by the very timeconsuming collection of manually expert-annotated data. Moreover,…

Image and Video Processing · Electrical Eng. & Systems 2024-11-06 Robin Trombetta , Olivier Rouvière , Carole Lartizien

From self-supervised, vision-only models to contrastive visual-language frameworks, computational pathology has rapidly evolved in recent years. Generative AI "co-pilots" now demonstrate the ability to mine subtle, sub-visual tissue cues…

Computer Vision and Pattern Recognition · Computer Science 2025-02-13 Mohsin Bilal , Aadam , Manahil Raza , Youssef Altherwy , Anas Alsuhaibani , Abdulrahman Abduljabbar , Fahdah Almarshad , Paul Golding , Nasir Rajpoot