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The distribution shifts between training and test data typically undermine the performance of models. In recent years, lots of work pays attention to domain generalization (DG) where distribution shifts exist, and target data are unseen.…

Machine Learning · Computer Science 2024-01-05 Wang Lu , Jindong Wang , Yidong Wang , Xing Xie

Distributional shift between domains poses great challenges to modern machine learning algorithms. The domain generalization (DG) signifies a popular line targeting this issue, where these methods intend to uncover universal patterns across…

Computer Vision and Pattern Recognition · Computer Science 2023-10-05 Hao Chen , Qi Zhang , Zenan Huang , Haobo Wang , Junbo Zhao

Machine learning algorithms have the potential to improve patient outcomes in digital pathology. However, generalization of these tools is currently limited by sensitivity to variations in tissue preparation, staining procedures and…

Whole Slide Images (WSIs) in digital pathology are used to diagnose cancer subtypes. The difference in procedures to acquire WSIs at various trial sites gives rise to variability in the histopathology images, thus making consistent…

Image and Video Processing · Electrical Eng. & Systems 2022-04-07 Milad Sikaroudi , Shahryar Rahnamayan , H. R. Tizhoosh

The variation in histologic staining between different medical centers is one of the most profound challenges in the field of computer-aided diagnosis. The appearance disparity of pathological whole slide images causes algorithms to become…

Image and Video Processing · Electrical Eng. & Systems 2024-04-05 Martin J. Hetz , Tabea-Clara Bucher , Titus J. Brinker

Domain generalization (DG) for object detection aims to enhance detectors' performance in unseen scenarios. This task remains challenging due to complex variations in real-world applications. Recently, diffusion models have demonstrated…

Computer Vision and Pattern Recognition · Computer Science 2025-06-05 Boyong He , Yuxiang Ji , Qianwen Ye , Zhuoyue Tan , Liaoni Wu

Recent advances in deep learning for medical image segmentation demonstrate expert-level accuracy. However, in clinically realistic environments, such methods have marginal performance due to differences in image domains, including…

Computer Vision and Pattern Recognition · Computer Science 2019-06-13 Ling Zhang , Xiaosong Wang , Dong Yang , Thomas Sanford , Stephanie Harmon , Baris Turkbey , Holger Roth , Andriy Myronenko , Daguang Xu , Ziyue Xu

Tissue phenotyping is a fundamental computational pathology (CPath) task in learning objective characterizations of histopathologic biomarkers in anatomic pathology. However, whole-slide imaging (WSI) poses a complex computer vision problem…

Motivation: Digitization of pathology laboratories through digital slide scanners and advances in deep learning approaches for objective histological assessment have resulted in rapid progress in the field of computational pathology (CPath)…

Machine Learning · Computer Science 2022-01-31 Alex Foote , Amina Asif , Nasir Rajpoot , Fayyaz Minhas

Domain Generalization (DG) aims to learn a model that can generalize well to unseen target domains from a set of source domains. With the idea of invariant causal mechanism, a lot of efforts have been put into learning robust causal effects…

Computer Vision and Pattern Recognition · Computer Science 2022-10-07 Qiaowei Miao , Junkun Yuan , Kun Kuang

In recent years, deep neural networks (DNNs) have demonstrated remarkable performance in pathology applications, potentially even outperforming expert pathologists due to their ability to learn subtle features from large datasets. One…

Image and Video Processing · Electrical Eng. & Systems 2024-09-16 Siyu , Lin , Haowen Zhou , Richard J. Cote , Mark Watson , Ramaswamy Govindan , Changhuei Yang

Domain generalization (DG) is the challenging and topical problem of learning models that generalize to novel testing domains with different statistics than a set of known training domains. The simple approach of aggregating data from all…

Computer Vision and Pattern Recognition · Computer Science 2019-12-09 Da Li , Jianshu Zhang , Yongxin Yang , Cong Liu , Yi-Zhe Song , Timothy M. Hospedales

Domain generalization (DG) tends to alleviate the poor generalization capability of deep neural networks by learning model with multiple source domains. A classical solution to DG is domain augmentation, the common belief of which is that…

Computer Vision and Pattern Recognition · Computer Science 2023-03-24 Fangrui Lv , Jian Liang , Shuang Li , Jinming Zhang , Di Liu

Generalizability is a concern when applying a deep learning (DL) model trained on one dataset to other datasets. Training a universal model that works anywhere, anytime, for anybody is unrealistic. In this work, we demonstrate the…

Medical Physics · Physics 2020-04-20 Xiao Liang , Dan Nguyen , Steve Jiang

Histopathological images contain rich phenotypic information that can be used to monitor underlying mechanisms contributing to diseases progression and patient survival outcomes. Recently, deep learning has become the mainstream…

Image and Video Processing · Electrical Eng. & Systems 2020-10-28 Chetan L. Srinidhi , Ozan Ciga , Anne L. Martel

Recent breakthroughs in self-supervised learning have enabled the use of large unlabeled datasets to train visual foundation models that can generalize to a variety of downstream tasks. While this training paradigm is well suited for the…

As machine learning evolves, domain generalization (DG) and domain adaptation (DA) have become crucial for enhancing model robustness across diverse environments. Contrastive Language-Image Pretraining (CLIP) plays a significant role in…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Jindong Li , Yongguang Li , Yali Fu , Jiahong Liu , Yixin Liu , Menglin Yang , Irwin King

Digital pathology is one of the most significant developments in modern medicine. Pathological examinations are the gold standard of medical protocols and play a fundamental role in diagnosis. Recently, with the advent of digital scanners,…

Image and Video Processing · Electrical Eng. & Systems 2021-12-09 Mahdi Arab Loodaricheh , Nader Karimi , Shadrokh Samavi

The vast amount of health data has been continuously collected for each patient, providing opportunities to support diverse healthcare predictive tasks such as seizure detection and hospitalization prediction. Existing models are mostly…

Machine Learning · Computer Science 2023-02-16 Chaoqi Yang , M. Brandon Westover , Jimeng Sun

With the increasing utilization of deep learning in outdoor settings, its robustness needs to be enhanced to preserve accuracy in the face of distribution shifts, such as compression artifacts. Data augmentation is a widely used technique…

Computer Vision and Pattern Recognition · Computer Science 2023-10-03 Shohei Enomoto , Monikka Roslianna Busto , Takeharu Eda