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Survival analysis is an integral part of the statistical toolbox. However, while most domains of classical statistics have embraced deep learning, survival analysis only recently gained some minor attention from the deep learning community.…

The conditional survival function of a time-to-event outcome subject to censoring and truncation is a common target of estimation in survival analysis. This parameter may be of scientific interest and also often appears as a nuisance in…

Methodology · Statistics 2024-08-20 Charles J. Wolock , Peter B. Gilbert , Noah Simon , Marco Carone

Improving the quality of end-of-life care for hospitalized patients is a priority for healthcare organizations. Studies have shown that physicians tend to over-estimate prognoses, which in combination with treatment inertia results in a…

Computers and Society · Computer Science 2017-11-20 Anand Avati , Kenneth Jung , Stephanie Harman , Lance Downing , Andrew Ng , Nigam H. Shah

We propose a novel method for predicting time-to-event in the presence of cure fractions based on flexible survivals models integrated into a deep neural network framework. Our approach allows for non-linear relationships and…

Machine Learning · Statistics 2024-11-11 Victor Medina-Olivares , Stefan Lessmann , Nadja Klein

Observational cohort data is an important source of information for understanding the causal effects of treatments on survival and the degree to which these effects are mediated through changes in disease-related risk factors. However,…

Methodology · Statistics 2026-05-20 Saurabh Bhandari , Michael J. Daniels , Juned Siddique

Although timely sepsis diagnosis and prompt interventions in Intensive Care Unit (ICU) patients are associated with reduced mortality, early clinical recognition is frequently impeded by non-specific signs of infection and failure to detect…

Machine Learning · Computer Science 2018-06-28 Tony Wang , Tom Velez , Emilia Apostolova , Tim Tschampel , Thuy L. Ngo , Joy Hardison

The timeliness of detection of a sepsis event in progress is a crucial factor in the outcome for the patient. Machine learning models built from data in electronic health records can be used as an effective tool for improving this…

We consider the task of learning individual-specific intensities of counting processes from a set of static variables and irregularly sampled time series. We introduce a novel modelization approach in which the intensity is the solution to…

Machine Learning · Statistics 2024-06-05 Linus Bleistein , Van-Tuan Nguyen , Adeline Fermanian , Agathe Guilloux

Survival analysis is widely used as a technique to model time-to-event data when some data is censored, particularly in healthcare for predicting future patient risk. In such settings, survival models must be both accurate and interpretable…

Machine Learning · Computer Science 2024-04-24 Mike Van Ness , Madeleine Udell

Survival analysis is a cornerstone of clinical research by modeling time-to-event outcomes such as metastasis, disease relapse, or patient death. Unlike standard tabular data, survival data often come with incomplete event information due…

Machine Learning · Computer Science 2026-02-06 Marie Brockschmidt , Maresa Schröder , Stefan Feuerriegel

Cardiovascular diseases, including Heart Failure (HF), remain a leading global cause of mortality, often evading early detection. In this context, accessible and effective risk assessment is indispensable. Traditional approaches rely on…

Signal Processing · Electrical Eng. & Systems 2024-03-26 Sergio González , Abel Ko-Chun Yi , Wan-Ting Hsieh , Wei-Chao Chen , Chun-Li Wang , Victor Chien-Chia Wu , Shang-Hung Chang

Deep learning survival models often outperform classical methods in time-to-event predictions, particularly in personalized medicine, but their "black box" nature hinders broader adoption. We propose a framework for gradient-based…

Machine Learning · Statistics 2025-02-10 Sophie Hanna Langbein , Niklas Koenen , Marvin N. Wright

The prediction of disease risk factors can screen vulnerable groups for effective prevention and treatment, so as to reduce their morbidity and mortality. Machine learning has a great demand for high-quality labeling information, and…

Machine Learning · Computer Science 2024-06-26 Yang Lin , Muqing Li , Ziyi Zhu , Yinqiu Feng , Lingxi Xiao , Zexi Chen

The ability to perform accurate prognosis of patients is crucial for proactive clinical decision making, informed resource management and personalised care. Existing outcome prediction models suffer from a low recall of infrequent positive…

Patients who suffer an acute coronary syndrome are at elevated risk for adverse cardiovascular events such as myocardial infarction and cardiovascular death. Accurate assessment of this risk is crucial to their course of care. We focus on…

Machine Learning · Computer Science 2020-03-26 Divya Shanmugam , Davis Blalock , John Guttag

Clinical decision support systems (CDSS) are widely used to assist with medical decision making. However, CDSS typically require manually curated rules and other data which are difficult to maintain and keep up-to-date. Recent systems…

Human-Computer Interaction · Computer Science 2020-11-20 Zhuochen Jin , Jingshun Yang , Shuyuan Cui , David Gotz , Jimeng Sun , Nan Cao

Credit risk assessment is a crucial aspect of financial decision-making, enabling institutions to predict the likelihood of default and make informed lending decisions. Two prominent methodologies in credit risk modeling are logistic…

Applications · Statistics 2026-04-30 Cheng Lee , Hsi Lee

Joint modeling of longitudinal and survival data has become increasingly important in medical research, particularly for understanding disease progression in chronic conditions where both repeated biomarker measurements and time-to-event…

Methodology · Statistics 2025-12-30 Nithisha Suryadevara , Vivek Reddy Srigiri

In modern building infrastructures, the chance to devise adaptive and unsupervised data-driven health monitoring systems is gaining in popularity due to the large availability of big data from low-cost sensors with communication…

Motivated by conflicting conclusions regarding hydrocortisone's treatment effect on ICU patients with vasopressor-dependent septic shock, we developed a novel instrumental variable (IV) estimator to assess the average treatment effect (ATE)…

Methodology · Statistics 2025-03-18 Runjia Li , Victor B. Talisa , Chung-Chou H. Chang
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