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The global population is aging rapidly, and aging is a major risk factor for various diseases. It is an important task to predict how each individual's brain will age, as the brain supports many human functions. This capability can greatly…

Neurons and Cognition · Quantitative Biology 2025-12-05 Yifan Li , Javad Sohankar , Ji Luo , Jing Li , Yi Su

The rapid development in information technology has immensely contributed to the use of modern approaches for visualizing volumetric data. Consequently, medical volume visualization is increasingly attracting attention towards achieving an…

Computational Geometry · Computer Science 2012-11-27 A. M. Adeshina , R. Hashim , N. E. A. Khalid , Siti Z. Z. Abidin

We propose a novel machine learning strategy for studying neuroanatomical shape variation. Our model works with volumetric binary segmentation images, and requires no pre-processing such as the extraction of surface points or a mesh. The…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Evan M. Yu , Mert R. Sabuncu

Privacy protection in medical data is a legitimate obstacle for centralized machine learning applications. Here, we propose a client-server image segmentation system which allows for the analysis of multi-centric medical images while…

Computer Vision and Pattern Recognition · Computer Science 2023-06-21 Bach Kim , Jose Dolz , Pierre-Marc Jodoin , Christian Desrosiers

In recent years, deep learning has shown great promise in the automated detection and classification of brain tumors from MRI images. However, achieving high accuracy and computational efficiency remains a challenge. In this research, we…

Image and Video Processing · Electrical Eng. & Systems 2025-07-10 Daniel Onah , Ravish Desai

Understanding brain disorders is crucial for accurate clinical diagnosis and treatment. Recent advances in Multimodal Large Language Models (MLLMs) offer a promising approach to interpreting medical images with the support of text…

Image and Video Processing · Electrical Eng. & Systems 2025-06-03 Jing Zhang , Xiaowei Yu , Yanjun Lyu , Lu Zhang , Tong Chen , Chao Cao , Yan Zhuang , Minheng Chen , Tianming Liu , Dajiang Zhu

Every year, millions of brain MRI scans are acquired in hospitals, which is a figure considerably larger than the size of any research dataset. Therefore, the ability to analyse such scans could transform neuroimaging research. Yet, their…

Image and Video Processing · Electrical Eng. & Systems 2023-03-29 Benjamin Billot , Colin Magdamo , You Cheng , Steven E. Arnold , Sudeshna Das , Juan. E. Iglesias

Fully immersive virtual reality (VR) has the potential to improve neurosurgical planning. For example, it may offer 3D visualizations of relevant anatomical structures with complex shapes, such as blood vessels and tumors. However, there is…

Human-Computer Interaction · Computer Science 2019-08-15 Lukas D. J. Fiederer , Hisham Alwanni , Martin Völker , Oliver Schnell , Jürgen Beck , Tonio Ball

Non-rigid cortical registration is an important and challenging task due to the geometric complexity of the human cortex and the high degree of inter-subject variability. A conventional solution is to use a spherical representation of…

Image and Video Processing · Electrical Eng. & Systems 2020-07-28 Jieyu Cheng , Adrian V. Dalca , Bruce Fischl , Lilla Zollei

Whole-brain parcellation from MRI is a critical yet challenging task due to the complexity of subdividing the brain into numerous small, irregular shaped regions. Traditionally, template-registration methods were used, but recent advances…

Computer Vision and Pattern Recognition · Computer Science 2026-01-15 Yucheng Li , Xiaofan Wang , Junyi Wang , Yijie Li , Xi Zhu , Mubai Du , Dian Sheng , Wei Zhang , Fan Zhang

Purpose: Conventional automated segmentation of the head anatomy in MRI distinguishes different brain and non-brain tissues based on image intensities and prior tissue probability maps (TPM). This works well for normal head anatomies, but…

Image and Video Processing · Electrical Eng. & Systems 2021-05-20 Lukas Hirsch , Yu Huang , Lucas C Parra

Machine learning provides a valuable tool for analyzing high-dimensional functional neuroimaging data, and is proving effective in predicting various neurological conditions, psychiatric disorders, and cognitive patterns. In functional…

Machine Learning · Computer Science 2024-11-25 Anwar Said , Roza G. Bayrak , Tyler Derr , Mudassir Shabbir , Daniel Moyer , Catie Chang , Xenofon Koutsoukos

Many functional and structural neuroimaging studies call for accurate morphometric segmentation of different brain structures starting from image intensity values of MRI scans. Current automatic (multi-) atlas-based segmentation strategies…

Image and Video Processing · Electrical Eng. & Systems 2019-09-27 Dennis Bontempi , Sergio Benini , Alberto Signoroni , Michele Svanera , Lars Muckli

Volumetric medical image segmentation is a fundamental problem in medical image analysis where the objective is to accurately classify a given 3D volumetric medical image with voxel-level precision. In this work, we propose a novel…

Image and Video Processing · Electrical Eng. & Systems 2024-10-22 Daniya Najiha Abdul Kareem , Mustansar Fiaz , Noa Novershtern , Jacob Hanna , Hisham Cholakkal

Deep learning has emerged as a pivotal tool for accelerating research in the life sciences, with the low-level processing of biomedical images (e.g., registration, fusion, restoration, super-resolution) being one of its most critical…

Computational Engineering, Finance, and Science · Computer Science 2025-09-29 Gaole Dai , Chenghao Zhou , Yu Zhou , Rongyu Zhang , Yuan Zhang , Chengkai Hou , Tiejun Huang , Jianxu Chen , Shanghang Zhang

Skull-stripping separates the skull region of the head from the soft brain tissues. In many cases of brain image analysis, this is an essential preprocessing step in order to improve the final result. This is true for both registration and…

Computer Vision and Pattern Recognition · Computer Science 2012-04-03 Stefan Bauer , Lutz-P. Nolte , Mauricio Reyes

Automatic prostate segmentation is an important step in computer-aided diagnosis of prostate cancer and treatment planning. Existing methods of prostate segmentation are based on deep learning models which have a large size and lack of…

We present a multi-scale differentiable brain modeling workflow utilizing BrainPy, a unique differentiable brain simulator that combines accurate brain simulation with powerful gradient-based optimization. We leverage this capability of…

Neural and Evolutionary Computing · Computer Science 2024-09-26 Chaoming Wang , Muyang Lyu , Tianqiu Zhang , Sichao He , Si Wu

Clinical diagnostic workups typically follow a modality escalation pathway: after initial clinical evaluation, clinicians begin with routine structural imaging (e.g., MRI), selectively add sequences such as FLAIR or T2 to refine the…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Guangqian Yang , Tong Ding , Wenlong Hou , Yue Xun , Ye Du , Qian Niu , Shujun Wang

Brain imaging analysis is crucial for diagnosing and treating brain disorders, and multimodal large language models (MLLMs) are increasingly supporting it. However, current brain imaging visual question-answering (VQA) benchmarks either…

Computer Vision and Pattern Recognition · Computer Science 2025-12-29 Zhihao Peng , Cheng Wang , Shengyuan Liu , Zhiying Liang , Zanting Ye , Minjie Ju , PeterYM Woo , Yixuan Yuan