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Large language models (LLMs), such as GPT-4, PaLM, and LLaMa, have been shown to achieve remarkable performance across a variety of natural language tasks. Recent advancements in instruction tuning bring LLMs with ability in following…

Computation and Language · Computer Science 2023-09-12 Vu-Thuan Doan , Quoc-Truong Truong , Duc-Vu Nguyen , Vinh-Tiep Nguyen , Thuy-Ngan Nguyen Luu

Large-scale language models (LLMs) like ChatGPT have demonstrated impressive abilities in generating responses based on human instructions. However, their use in the medical field can be challenging due to their lack of specific, in-depth…

Computation and Language · Computer Science 2025-02-25 Yubo Wang , Xueguang Ma , Wenhu Chen

Large language models (LLMs) have shown substantial progress in natural language understanding and generation, proving valuable especially in the medical field. Despite advancements, challenges persist due to the complexity and diversity…

Computation and Language · Computer Science 2024-10-18 Yusheng Liao , Shuyang Jiang , Zhe Chen , Yanfeng Wang , Yu Wang

The recent success of large language models (LLMs) has paved the way for their adoption in the high-stakes domain of healthcare. Specifically, the application of LLMs in patient-trial matching, which involves assessing patient eligibility…

Artificial Intelligence · Computer Science 2023-12-18 Mauro Nievas , Aditya Basu , Yanshan Wang , Hrituraj Singh

Large language models (LLMs) are initially pretrained for broad capabilities and then finetuned with instruction-following datasets to improve their performance in interacting with humans. Despite advances in finetuning, a standardized…

Computation and Language · Computer Science 2024-07-30 Yihan Cao , Yanbin Kang , Chi Wang , Lichao Sun

Proprietary Large Language Models (LLMs), such as ChatGPT, have garnered significant attention due to their exceptional capabilities in handling a diverse range of tasks. Recent studies demonstrate that open-sourced smaller foundational…

Computation and Language · Computer Science 2023-10-10 Yue Zhang , Leyang Cui , Deng Cai , Xinting Huang , Tao Fang , Wei Bi

Large language models (LLMs) holds significant promise in achieving general medication recommendation systems owing to their comprehensive interpretation of clinical notes and flexibility to medication encoding. We evaluated both…

Information Retrieval · Computer Science 2025-08-05 Zihao Zhao , Chenxiao Fan , Junlong Liu , Zheng Wang , Xiangnan He , Chongming Gao , Juan Li , Fuli Feng

Large language models (LLMs) have demonstrated strong performance on medical benchmarks, including question answering and diagnosis. To enable their use in clinical settings, LLMs are typically further adapted through continued pretraining…

Fine-tuning large language models (LLMs) is essential for enhancing their performance on specific tasks but is often resource-intensive due to redundant or uninformative data. To address this inefficiency, we introduce DELIFT (Data…

Computation and Language · Computer Science 2025-03-21 Ishika Agarwal , Krishnateja Killamsetty , Lucian Popa , Marina Danilevksy

Adapting Large Language Models for Recommendation (LLM4Rec) has shown promising results. However, the challenges of deploying LLM4Rec in real-world scenarios remain largely unexplored. In particular, recommender models need incremental…

Information Retrieval · Computer Science 2024-07-31 Tianhao Shi , Yang Zhang , Zhijian Xu , Chong Chen , Fuli Feng , Xiangnan He , Qi Tian

Large language models (LLMs) such as ChatGPT have seen widespread adoption due to their strong instruction-following abilities. Developing these LLMs involves a complex yet poorly understood workflow requiring training with human feedback.…

The language ability of Large Language Models (LLMs) is often unbalanced towards English because of the imbalance in the distribution of the pre-training data. This disparity is demanded in further fine-tuning and affecting the…

Computation and Language · Computer Science 2024-10-30 Leonardo Ranaldi , Giulia Pucci , Andre Freitas

Recently, Large Language Models (LLMs) have showcased remarkable capabilities in natural language understanding. While demonstrating proficiency in everyday conversations and question-answering situations, these models frequently struggle…

Computation and Language · Computer Science 2023-08-28 Chaoyi Wu , Weixiong Lin , Xiaoman Zhang , Ya Zhang , Yanfeng Wang , Weidi Xie

Large Language Models are traditionally finetuned on large instruction datasets. However recent studies suggest that small, high-quality datasets can suffice for general purpose instruction following. This lack of consensus surrounding…

Machine Learning · Computer Science 2023-12-29 Aditi Jha , Sam Havens , Jeremy Dohmann , Alex Trott , Jacob Portes

Despite the effectiveness of data selection for large language models (LLMs) during pretraining and instruction fine-tuning phases, improving data efficiency in supervised fine-tuning (SFT) for specialized domains poses significant…

Computation and Language · Computer Science 2024-12-06 Yu Yang , Siddhartha Mishra , Jeffrey N Chiang , Baharan Mirzasoleiman

Large language models (LLMs) often fail to ask effective questions under uncertainty, making them unreliable in domains where proactive information-gathering is essential for decision-making. We present ALignment via Fine-grained…

$\textbf{Objectives}$: Large Language Models (LLMs) such as ChatGPT and Med-PaLM have excelled in various medical question-answering tasks. However, these English-centric models encounter challenges in non-English clinical settings,…

Computation and Language · Computer Science 2024-01-31 Jiageng Wu , Xian Wu , Zhaopeng Qiu , Minghui Li , Yingying Zhang , Yefeng Zheng , Changzheng Yuan , Jie Yang

This paper surveys research works in the quickly advancing field of instruction tuning (IT), which can also be referred to as supervised fine-tuning (SFT)\footnote{In this paper, unless specified otherwise, supervised fine-tuning (SFT) and…

Computation and Language · Computer Science 2025-10-07 Shengyu Zhang , Linfeng Dong , Xiaoya Li , Sen Zhang , Xiaofei Sun , Shuhe Wang , Jiwei Li , Runyi Hu , Tianwei Zhang , Fei Wu , Guoyin Wang

Large Language Models (LLMs) are expected to significantly contribute to patient care, diagnostics, and administrative processes. Emerging biomedical LLMs aim to address healthcare-specific challenges, including privacy demands and…

Computation and Language · Computer Science 2025-10-14 Amin Dada , Marie Bauer , Amanda Butler Contreras , Osman Alperen Koraş , Constantin Marc Seibold , Kaleb E Smith , Jens Kleesiek

Large language models (LLMs) achieve remarkable advancements by leveraging tools to interact with environments, a critical step toward generalized AI. However, the standard supervised fine-tuning (SFT) approach, which relies on large-scale…

Computation and Language · Computer Science 2025-08-27 Junjie Ye , Yilong Wu , Sixian Li , Yuming Yang , Zhiheng Xi , Tao Gui , Qi Zhang , Xuanjing Huang , Peng Wang , Zhongchao Shi , Jianping Fan , Zhengyin Du
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