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Human cognitive responses, behavioral responses, and disease dynamics co-evolve over the course of any disease outbreak, and can result in complex feedbacks. We present a dynamic agent-based model that explicitly couples the spread of…

We consider the effect of inducement to vaccinate during the spread of an infectious disease on complex networks. Suppose that public resources are finite and that only a small proportion of individuals can be vaccinated freely (complete…

Physics and Society · Physics 2015-03-30 Hai-Feng Zhang , Pan-Pan Shu , Ming Tang , Michael Small

This paper presents a Koopman-based framework for early outbreak detection and intervention selection in a multi-agent epidemic simulation. Agents exhibit mobility patterns, heterogeneous susceptibility, immunity-dependent viral load…

Multiagent Systems · Computer Science 2026-05-05 Florin Leon

In this paper we introduce an agent-based model together with a particle filter approach for studying the spread of COVID-19. Investigations are performed on the metropolis of Tokyo, but other cities, regions or countries could have been…

Numerical Analysis · Mathematics 2021-09-02 C. Sun , S. Richard , T. Miyoshi

Mitigation strategies that remove infectious individuals from the greater population have to balance their efficacy with the economic effects associated with quarantine and have to contend with the limited resources available to the public…

Quantitative Methods · Quantitative Biology 2020-12-09 Ted Londner , Jonathan Saunders , Dieter W. Schuldt , Bill Streilein

Vaccination campaigns have saved thousands of lives, reaching the farthest places in the world. These campaigns have required substantial investments and accurate coordination between several actors within the vaccine supply chain. Despite…

The COVID-19 pandemic left its unique mark on the 21st century as one of the most significant disasters in history, triggering governments all over the world to respond with a wide range of interventions. However, these restrictions come…

Computational Engineering, Finance, and Science · Computer Science 2021-06-02 Assem Zhunis , Tung-Duong Mai , Sundong Kim

In the early stage of an infectious disease outbreak, public health strategies tend to gravitate towards non-pharmaceutical interventions (NPIs) given the time required to develop targeted treatments and vaccines. One of the most common…

Quantitative Methods · Quantitative Biology 2024-12-20 Yunyi Cai , Weiyi Wang , Lanlan Yu , Ruixiang Wang , Gui-Quan Sun , Allisandra G. Kummer , Paulo C. Ventura , Jiancheng Lv , Marco Ajelli , Quan-Hui Liu

Natural Immune system plays a vital role in the survival of the all living being. It provides a mechanism to defend itself from external predates making it consistent systems, capable of adapting itself for survival incase of changes. The…

Artificial Intelligence · Computer Science 2011-03-11 Tejbanta Singh Chingtham , G. Sahoo , M. K. Ghose

Modelling and computational methods have been essential in advancing quantitative science, especially in the past two decades with the availability of vast amount of complex, voluminous, and heterogeneous data. In particular, there has been…

Multiagent Systems · Computer Science 2020-07-09 Affan Shoukat , Seyed M. Moghadas

The World Health Organisation (WHO) has very strongly recommended testing and isolation as a strategy for controlling the ongoing COVID-19 pandemic. The goal of this paper is to quantify the effects of detection and isolation in formal…

Populations and Evolution · Quantitative Biology 2020-06-09 Palash Sarkar

In this work we propose and investigate a new strategy of vaccination, which we call "dynamic vaccination". In our model, susceptible people become aware that one or more of their contacts are infected, and thereby get vaccinated with…

Physics and Society · Physics 2019-01-09 L. G. Alvarez-Zuzek , M. A. Di Muro , S. Havlin , L. A. Braunstein

This methods article concerns analysing data generated from running experiments on agent based models to study industries and organisations. It demonstrates that when researchers study virtual ecologies they can and should discard…

Applications · Statistics 2024-09-27 Thomas Chesney , Tim Gruchman , Robert Pasley , Altricia Dawson , Stefan Gold

Case isolation, that is, detection and isolation of infected individuals in order to prevent spread, is a strategy to curb infectious disease epidemics. Here, we study the efficiency of a case isolation strategy subject to time delays in…

Optimization and Control · Mathematics 2022-09-20 Jonas Hansson , Alain Govaert , Richard Pates , Emma Tegling , Kristian Soltesz

The topic of finding effective strategy to halt virus in complex network is of current interest. We propose an immunization strategy for seasonal epidemics that occur periodically. Based on the local information of the infection status from…

Applications · Statistics 2015-06-22 Shu Yan , Shaoting Tang , Sen Pei , Shijin Jiang , Zhiming Zheng

We study the impact of vaccination on the risk of epidemics spreading through structured networks using the cavity method of statistical physics. We relax the assumption that vaccination prevents all transmission of a disease used in…

Physics and Society · Physics 2022-03-23 Christian John Hurry , Alexander Mozeika , Alessia Annibale

Oncolytic virotherapy, utilizing genetically modified viruses to combat cancer and trigger anti-cancer immune responses, has garnered significant attention in recent years. In our previous work arXiv:2305.12386, we developed a stochastic…

Populations and Evolution · Quantitative Biology 2026-04-23 David Morselli , Marcello E. Delitala , Adrianne L. Jenner , Federico Frascoli

The propagation of model epidemics on a small-world network under the action of immunization is studied. Although the connectivity in this kind of networks is rather uniform, a vaccination strategy focused on the best connected individuals…

Statistical Mechanics · Physics 2009-11-07 Damian H. Zanette , Marcelo Kuperman

Our study presents an intermediate-level modeling approach that bridges the gap between complex Agent-Based Models (ABMs) and traditional compartmental models for infectious diseases. We introduce "super-agents" to simulate infection spread…

Computers and Society · Computer Science 2024-03-12 Amir Mohammad Esmaieeli Sikaroudi , Alon Efrat , Michael Chertkov

Many laypeople are motivated to improve the health behavior of their family or friends but do not know where to start, especially if the health behavior is potentially stigmatizing or controversial. We present an approach that uses virtual…