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The spread of COVID-19 has been thwarted in most countries through non-pharmaceutical interventions. In particular, the most effective measures in this direction have been the stay-at-home and closure strategies of businesses and schools.…

Physics and Society · Physics 2022-05-04 G. Dimarco , G. Toscani , M. Zanella

Restrictions on social and economic activities, as well as vaccinations, have been a key intervention in containing the COVID-19 epidemic. Our work focuses on better understanding the options available to policymakers under the conditions…

Optimization and Control · Mathematics 2023-09-07 Franco Galante , Chiara Ravazzi , Michele Garetto , Emilio Leonardi

Advances in computing power and data availability have led to growing sophistication in mechanistic mathematical models of social dynamics. Increasingly these models are used to inform real-world policy decision-making, often with…

This paper analyses the optimal control of infectious disease propagation using a classic susceptible-infected-recovered (SIR) model characterised by permanent immunity and the absence of available vaccines. The control is performed over a…

Optimization and Control · Mathematics 2024-06-12 Rocío Balderrama , Mariana Inés Prieto , Constanza Sánchez de la Vega , Federico Vazquez

We propose a new method to immunize populations or computer networks against epidemics which is more efficient than any method considered before. The novelty of our method resides in the way of determining the immunization targets. First we…

Physics and Society · Physics 2015-06-03 Christian M. Schneider , Tamara Mihaljev , Hans J. Herrmann

When considering airborne epidemic spreading in social systems, a natural connection arises between mobility and epidemic contacts. As individuals travel, possibilities to encounter new people either at the final destination or during the…

Physics and Society · Physics 2024-05-10 Jesús A. Moreno López , Sandro Meloni , Jose J. Ramasco

This paper revisits a longstanding problem of interest concerning the distributed control of an epidemic process on human contact networks. Due to the stochastic nature and combinatorial complexity of the problem, finding optimal policies…

Optimization and Control · Mathematics 2022-12-12 Mohammad Mubarak , Cameron Nowzari

Epidemics seldom occur as isolated phenomena. Typically, two or more viral agents spread within the same host population and may interact dynamically with each other. We present a general model where two viral agents interact via an…

Agent-based modeling plays an essential role in gaining insights into biology, sociology, economics, and other fields. However, many existing agent-based simulation platforms are not suitable for large-scale studies due to the low…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-04-25 Lukas Breitwieser , Ahmad Hesam , Fons Rademakers , Juan Gómez Luna , Onur Mutlu

The pursuit of strategies that minimize the number of individuals needing vaccination to control an outbreak is a well-established area of study in mathematical epidemiology. However, for certain diseases, public policy tends to prioritize…

Populations and Evolution · Quantitative Biology 2026-01-30 J. Orestes Cerdeira , Fabio A. C. C. Chalub , Matheus Hansen

Agent-based modelling is a valuable approach for systems whose behaviour is driven by the interactions between distinct entities. They have shown particular promise as a means of modelling crowds of people in streets, public transport…

Multiagent Systems · Computer Science 2020-04-30 Nick Malleson , Kevin Minors , Le-Minh Kieu , Jonathan A. Ward , Andrew A. West , Alison Heppenstall

With a simple phenomenological metapopulation model, which characterizes the invasion process of an influenza pandemic from a source to a subpopulation at risk, we compare the efficiency of inter- and intra-population interventions in…

Physics and Society · Physics 2012-09-27 Lin Wang , Yan Zhang , Tianyi Huang , Xiang Li

In this paper, we propose a dynamical model to describe the transmission of COVID-19, which is spreading in China and many other countries. To avoid a larger outbreak in the worldwide, Chinese government carried out a series of strong…

Populations and Evolution · Quantitative Biology 2020-03-09 Jiwei Jia , Jian Ding , Siyu Liu , Guidong Liao , Jingzhi Li , Ben Duan , Guoqing Wang , Ran Zhang

For the development and optimization of agent-based models (ABMs) and rational agent-based models (RABMs), optimization algorithms such as reinforcement learning are extensively used. However, assessing the performance of RL-based ABMs and…

Machine Learning · Computer Science 2025-08-11 Rishabh Gaur , Gaurav Deshkar , Jayanta Kshirsagar , Harshal Hayatnagarkar , Janani Venugopalan

Vaccination and outbreak monitoring are essential tools for preventing and minimizing outbreaks of infectious diseases. Targeted strategies, where the individuals most important for monitoring or preventing outbreaks are selected for…

Physics and Society · Physics 2016-03-04 Enys Mones , Arkadiusz Stopczynski , Alex Pentland , Nathaniel Hupert , Sune Lehmann

We consider optimal vaccination protocol where the vaccine is in short supply. In this case, disease extinction results from a large and rare fluctuation. We show that the probability of such fluctuation can be exponentially increased by…

Populations and Evolution · Quantitative Biology 2013-05-29 M. Khasin , M. I. Dykman , B. Meerson

The main goal of this paper is to model the epidemic and flattening the infection curve of the social networks. Flattening the infection curve implies slowing down the spread of the disease and reducing the infection rate via…

Current models of COVID-19 transmission predict infection from reported or assumed interactions. Here we leverage high-resolution observations of interaction to simulate infectious processes. Ultra-Wide Radio Frequency Identification (RFID)…

Computers and Society · Computer Science 2022-01-24 Yi Zhang , Yudong Tao , Mei-Ling Shyu , Lynn K. Perry , Prem R. Warde , Daniel S. Messinger , Chaoming Song

Mechanistic simulators are an indispensable tool for epidemiology to explore the behavior of complex, dynamic infections under varying conditions and navigate uncertain environments. Agent-based models (ABMs) are an increasingly popular…

Enumerated threat agent lists have long driven biodefense priorities. The global SARS-CoV-2 pandemic demonstrated the limitations of searching for known threat agents as compared to a more agnostic approach. Recent technological advances…

Other Quantitative Biology · Quantitative Biology 2024-02-29 Andy Lin , Cameron Torres , Errett C. Hobbs , Jaydeep Bardhan , Stephen B. Aley , Charles T. Spencer , Karen L. Taylor , Tony Chiang