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Causal inference plays a crucial role in scientific research across multiple disciplines. Estimating causal effects, particularly the average treatment effect (ATE), from observational data has garnered significant attention. However,…

Cryptography and Security · Computer Science 2025-12-17 Quan Yuan , Xiaochen Li , Linkang Du , Min Chen , Mingyang Sun , Yunjun Gao , Shibo He , Jiming Chen , Zhikun Zhang

The average treatment effect (ATE) is widely used to evaluate the effectiveness of drugs and other medical interventions. In safety-critical applications like medicine, reliable inferences about the ATE typically require valid uncertainty…

Machine Learning · Computer Science 2025-10-13 Maresa Schröder , Justin Hartenstein , Stefan Feuerriegel

Experiment design has a rich history dating back over a century and has found many critical applications across various fields since then. The use and collection of users' data in experiments often involve sensitive personal information, so…

Cryptography and Security · Computer Science 2023-11-09 Wei-Ning Chen , Graham Cormode , Akash Bharadwaj , Peter Romov , Ayfer Özgür

Estimating heterogeneous treatment effects in domains such as healthcare or social science often involves sensitive data where protecting privacy is important. We introduce a general meta-algorithm for estimating conditional average…

Machine Learning · Statistics 2022-02-23 Fengshi Niu , Harsha Nori , Brian Quistorff , Rich Caruana , Donald Ngwe , Aadharsh Kannan

Patient data is widely used to estimate heterogeneous treatment effects and thus understand the effectiveness and safety of drugs. Yet, patient data includes highly sensitive information that must be kept private. In this work, we aim to…

Machine Learning · Computer Science 2025-03-06 Maresa Schröder , Valentyn Melnychuk , Stefan Feuerriegel

When it comes to preserving privacy in medical machine learning, two important considerations are (1) keeping data local to the institution and (2) avoiding inference of sensitive information from the trained model. These are often…

Computer Vision and Pattern Recognition · Computer Science 2020-04-15 Dominik Fay , Jens Sjölund , Tobias J. Oechtering

We are interested in estimating the effect of a treatment applied to individuals at multiple sites, where data is stored locally for each site. Due to privacy constraints, individual-level data cannot be shared across sites; the sites may…

Machine Learning · Computer Science 2023-04-04 Ruoxuan Xiong , Allison Koenecke , Michael Powell , Zhu Shen , Joshua T. Vogelstein , Susan Athey

The Private Aggregation of Teacher Ensembles (PATE) is an important private machine learning framework. It combines multiple learning models used as teachers for a student model that learns to predict an output chosen by noisy voting among…

Machine Learning · Computer Science 2021-09-20 Cuong Tran , My H. Dinh , Kyle Beiter , Ferdinando Fioretto

The estimation of conditional average treatment effects (CATEs) is an important topic in many scientific fields. CATEs can be estimated with high accuracy if data distributed across multiple parties are centralized. However, it is difficult…

Methodology · Statistics 2025-07-28 Yuji Kawamata , Ryoki Motai , Yukihiko Okada , Akira Imakura , Tetsuya Sakurai

Estimating causal effects from observational data is essential in fields such as medicine, economics and social sciences, where privacy concerns are paramount. We propose a general, model-agnostic framework for differentially private…

Machine Learning · Computer Science 2026-02-02 Christian Janos Lebeda , Mathieu Even , Aurélien Bellet , Julie Josse

Machine learning methods for estimating heterogeneous treatment effects (HTE) facilitate large-scale personalized decision-making across various domains such as healthcare, policy making, education, and more. Current machine learning…

Machine Learning · Computer Science 2024-06-25 Disha Makhija , Joydeep Ghosh , Yejin Kim

With the rapid digitalization of healthcare systems, there has been a substantial increase in the generation and sharing of private health data. Safeguarding patient information is essential for maintaining consumer trust and ensuring…

Artificial Intelligence · Computer Science 2026-01-27 Yazan Otoum , Amiya Nayak

Accurately estimating personalized treatment effects within a study site (e.g., a hospital) has been challenging due to limited sample size. Furthermore, privacy considerations and lack of resources prevent a site from leveraging…

Machine Learning · Statistics 2022-06-17 Xiaoqing Tan , Chung-Chou H. Chang , Ling Zhou , Lu Tang

Many applications of machine learning, such as human health research, involve processing private or sensitive information. Privacy concerns may impose significant hurdles to collaboration in scenarios where there are multiple sites holding…

Machine Learning · Computer Science 2021-02-24 Hafiz Imtiaz , Jafar Mohammadi , Anand D. Sarwate

Privacy data protection in the medical field poses challenges to data sharing, limiting the ability to integrate data across hospitals for training high-precision auxiliary diagnostic models. Traditional centralized training methods are…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Tian Bowen , Xu Zhengyang , Yin Zhihao , Wang Jingying , Yue Yutao

Collaborative graph analysis across multiple institutions is becoming increasingly popular. Realistic examples include social network analysis across various social platforms, financial transaction analysis across multiple banks, and…

Cryptography and Security · Computer Science 2024-06-03 Shang Liu , Yang Cao , Takao Murakami , Weiran Liu , Seng Pei Liew , Tsubasa Takahashi , Jinfei Liu , Masatoshi Yoshikawa

Machine learning models used for distributed architectures consisting of servers and clients require large amounts of data to achieve high accuracy. Data obtained from clients are collected on a central server for model training. However,…

Cryptography and Security · Computer Science 2025-09-18 Ozer Ozturk , Busra Buyuktanir , Gozde Karatas Baydogmus , Kazim Yildiz

Federated learning enables training a global machine learning model from data distributed across multiple sites, without having to move the data. This is particularly relevant in healthcare applications, where data is rife with personal,…

Cryptography and Security · Computer Science 2020-02-24 Olivia Choudhury , Aris Gkoulalas-Divanis , Theodoros Salonidis , Issa Sylla , Yoonyoung Park , Grace Hsu , Amar Das

The use of collaborative and decentralized machine learning techniques such as federated learning have the potential to enable the development and deployment of clinical risk predictions models in low-resource settings without requiring…

Machine Learning · Computer Science 2019-11-15 Stephen R. Pfohl , Andrew M. Dai , Katherine Heller

Some machine learning applications involve training data that is sensitive, such as the medical histories of patients in a clinical trial. A model may inadvertently and implicitly store some of its training data; careful analysis of the…

Machine Learning · Statistics 2017-03-06 Nicolas Papernot , Martín Abadi , Úlfar Erlingsson , Ian Goodfellow , Kunal Talwar
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