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Context: Verification and validation (V&V) activities make up 20 to 50 percent of the total development costs of a software system in practice. Test automation is proposed to lower these V&V costs but available research only provides…

Software Engineering · Computer Science 2016-02-04 Emil Alégroth , Robert Feldt , Pirjo Kolström

Large language models (LLMs) have made remarkable progress in code generation, but competitive programming remains a challenge. Recent training-based methods have improved code generation by using reinforcement learning (RL) with execution…

Software Engineering · Computer Science 2026-04-08 Lingxiao Tang , Muyang Ye , Zhaoyang Chu , Xiaoxue Ren , Zhongxin Liu , Lingfeng Bao , He Ye

Bayesian optimization (BO) is a popular approach for optimizing expensive-to-evaluate black-box objective functions. An important challenge in BO is its application to high-dimensional search spaces due in large part to the curse of…

Machine Learning · Computer Science 2025-05-27 Wei-Ting Tang , Joel A. Paulson

We present the EVONANO platform for the evolution of nanomedicines with application to anti-cancer treatments. EVONANO includes a simulator to grow tumours, extract representative scenarios, and then simulate nanoparticle transport through…

Neural and Evolutionary Computing · Computer Science 2021-02-02 Namid Stillman , Igor Balaz , Antisthenis Tsompanas , Marina Kovacevic , Sepinoud Azimi , Sebastien Lafond , Andrew Adamatzky , Sabine Hauert

Quantum computing holds the potential to provide speedups in solving complex problems that are currently difficult for classical computers. However, the realization of this potential is hindered by the issue of current hardware reliability,…

Quantum Physics · Physics 2025-04-29 Shay Manor , Millan Kumar , Priyank Behera , Azain Khalid , Oliver Zeng

Cancer subtyping is crucial for understanding the nature of tumors and providing suitable therapy. However, existing labelling methods are medically controversial, and have driven the process of subtyping away from teaching signals.…

Machine Learning · Computer Science 2022-11-15 Zheng Chen , Lingwei Zhu , Ziwei Yang , Takashi Matsubara

Machine learning (ML) approaches have been used to develop highly accurate and efficient applications in many fields including bio-medical science. However, even with advanced ML techniques, cancer classification using gene expression data…

Genomics · Quantitative Biology 2023-05-10 Mahmood Khalsan , Mu Mu , Eman Salih Al-Shamery , Lee Machado , Suraj Ajit , Michael Opoku Agyeman

REST APIs are widely used in industry, in all different kinds of domains. An example is Volkswagen AG, a German automobile manufacturer. Established testing approaches for REST APIs are time consuming, and require expertise from…

Software Engineering · Computer Science 2026-04-03 Andrea Arcuri , Alexander Poth , Olsi Rrjolli , Philip Garrett , Juan P. Galeotti

We present EvoSort, a general-purpose adaptive parallel parallel sorting framework accessible at the Python level. EvoSort employs a Genetic Algorithm (GA) to automatically discover and refine critical parameters, including insertion sort…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-01-05 Shashank Raj , Kalyanmoy Deb

It is imperative for testing to determine if the components within large-scale software systems operate functionally. Interaction testing involves designing a suite of tests, which guarantees to detect a fault if one exists among a small…

Neural and Evolutionary Computing · Computer Science 2020-02-14 Ryan E. Dougherty

This research aims to investigate the classification accuracy of various state-of-the-art image classification models across different categories of breast ultrasound images, as defined by the Breast Imaging Reporting and Data System…

Image and Video Processing · Electrical Eng. & Systems 2023-11-16 Malitha Gunawardhana , Norbert Zolek

In our study, we introduce a novel hybrid ensemble model that synergistically combines LSTM, BiLSTM, CNN, GRU, and GloVe embeddings for the classification of gene mutations in cancer. This model was rigorously tested using Kaggle's…

Quantitative Methods · Quantitative Biology 2024-05-21 Sanad Aburass , Osama Dorgham , Jamil Al Shaqsi

Background. Breast cancer screening programs using mammography have led to significant mortality reduction in high-income countries. However, many low- and middle-income countries lack resources for mammographic screening. Handheld breast…

Image and Video Processing · Electrical Eng. & Systems 2024-11-13 Arianna Bunnell , Dustin Valdez , Fredrik Strand , Yannik Glaser , Peter Sadowski , John A. Shepherd

This paper examines the potential for generative artificial intelligence (GenAI) to assist with internal review processes for research quality evaluations in UK higher education and particularly in preparation for the Research Excellence…

Computers and Society · Computer Science 2025-12-01 Gordon Fletcher , Saomai Vu Khan , Aldus Greenhill Fletcher

Large Language Models (LLMs) have demonstrated great potential in automating the generation of Verilog hardware description language code for hardware design. This automation is critical to reducing human effort in the complex and…

Hardware Architecture · Computer Science 2025-08-20 Ping Guo , Yiting Wang , Wanghao Ye , Yexiao He , Ziyao Wang , Xiaopeng Dai , Ang Li , Qingfu Zhang

Cancer survival prediction using multi-modal medical imaging presents a critical challenge in oncology, mainly due to the vulnerability of deep learning models to noise and protocol variations across imaging centers. Current approaches…

Image and Video Processing · Electrical Eng. & Systems 2025-05-06 Aiman Farooq , Azad Singh , Deepak Mishra , Santanu Chaudhury

Recent work such as AlphaEvolve has shown that combining LLM-driven optimization with evolutionary search can effectively improve programs, prompts, and algorithms across domains. In this paradigm, previously evaluated solutions are reused…

The diagnosed cases of Breast cancer is increasing annually and unfortunately getting converted into a high mortality rate. Cancer, at the early stages, is hard to detect because the malicious cells show similar properties (density) as…

Computer Vision and Pattern Recognition · Computer Science 2017-04-13 Deepti Ameta

Ultrasonography is an important routine examination for breast cancer diagnosis, due to its non-invasive, radiation-free and low-cost properties. However, the diagnostic accuracy of breast cancer is still limited due to its inherent…

Image and Video Processing · Electrical Eng. & Systems 2022-07-18 Yuhao Mo , Chu Han , Yu Liu , Min Liu , Zhenwei Shi , Jiatai Lin , Bingchao Zhao , Chunwang Huang , Bingjiang Qiu , Yanfen Cui , Lei Wu , Xipeng Pan , Zeyan Xu , Xiaomei Huang , Zaiyi Liu , Ying Wang , Changhong Liang

While deep learning methods have shown great promise in improving the effectiveness of prostate cancer (PCa) diagnosis by detecting suspicious lesions from trans-rectal ultrasound (TRUS), they must overcome multiple simultaneous challenges.…

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