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Related papers: Language models in molecular discovery

200 papers

Large language models (LLMs) are powerful artificial intelligence (AI) tools transforming how research is conducted. However, their use in research has been met with skepticism, due to concerns about hallucinations, biases and potential…

Artificial Intelligence · Computer Science 2025-07-08 Ruian Ke , Ruy M. Ribeiro

Although artificial intelligence (AI) has made significant progress in understanding molecules in a wide range of fields, existing models generally acquire the single cognitive ability from the single molecular modality. Since the hierarchy…

Machine Learning · Computer Science 2022-09-14 Bing Su , Dazhao Du , Zhao Yang , Yujie Zhou , Jiangmeng Li , Anyi Rao , Hao Sun , Zhiwu Lu , Ji-Rong Wen

Deep learning is now widely used in drug discovery, providing significant acceleration and cost reduction. As the most fundamental building block, molecular representation is essential for predicting molecular properties to enable various…

Machine Learning · Computer Science 2024-04-22 Haoqiang Guo , Sendong Zhao , Haochun Wang , Yanrui Du , Bing Qin

Model-Driven Engineering (MDE) has seen significant advancements with the integration of Machine Learning (ML) and Deep Learning (DL) techniques. Building upon the groundwork of previous investigations, our study provides a concise overview…

Software Engineering · Computer Science 2024-10-24 Juri Di Rocco , Davide Di Ruscio , Claudio Di Sipio , Phuong T. Nguyen , Riccardo Rubei

With the advent of large language models (LLMs), there is a growing interest in applying LLMs to scientific tasks. In this work, we conduct an experimental study to explore applicability of LLMs for configuring, annotating, translating,…

Human-Computer Interaction · Computer Science 2025-10-13 Orcun Yildiz , Tom Peterka

Master equations are of fundamental importance in modeling stochastic dynamical systems.However, solving master equations is challenging due to the exponential increase in the number of possible states or trajectories with the dimension of…

Machine Learning · Computer Science 2024-02-27 Chuanbo Liu , Jin Wang

This study analyzes the multiple functions of Large Language Models (LLMs) in transforming research and development (R&D) processes. By automating knowledge discovery, boosting hypothesis creation, integrating transdisciplinary insights,…

Computation and Language · Computer Science 2025-11-25 Raha Aghaei , Ali A. Kiaei , Mahnaz Boush , Mahan Rofoosheh , Mohammad Zavvar

Cognitive science faces ongoing challenges in research integration, formalization, conceptual clarity, and other areas, in part due to its multifaceted and interdisciplinary nature. Recent advances in artificial intelligence, particularly…

Artificial Intelligence · Computer Science 2026-03-03 Dirk U. Wulff , Rui Mata

Language models are increasingly becoming popular in AI-powered scientific IR systems. This paper evaluates popular scientific language models in handling (i) short-query texts and (ii) textual neighbors. Our experiments showcase the…

Information Retrieval · Computer Science 2022-03-30 Shruti Singh , Mayank Singh

Artificial intelligence (AI) agents are emerging as transformative tools in drug discovery, with the ability to autonomously reason, act, and learn through complicated research workflows. Building on large language models (LLMs) coupled…

Large Language Models offer new opportunities to devise automated implementation generation methods that can tackle problem solving activities beyond traditional methods, which require algorithmic specifications and can use only static…

Computation and Language · Computer Science 2025-01-06 Hashmath Shaik , Alex Doboli

Algorithm design is crucial for effective problem-solving across various domains. The advent of Large Language Models (LLMs) has notably enhanced the automation and innovation within this field, offering new perspectives and promising…

Machine Learning · Computer Science 2026-01-06 Fei Liu , Yiming Yao , Ping Guo , Zhiyuan Yang , Zhe Zhao , Xi Lin , Xialiang Tong , Kun Mao , Zhichao Lu , Zhenkun Wang , Mingxuan Yuan , Qingfu Zhang

This research investigates the application of Large Language Models (LLMs) to augment conversational agents in process mining, aiming to tackle its inherent complexity and diverse skill requirements. While LLM advancements present novel…

Artificial Intelligence · Computer Science 2023-07-20 Urszula Jessen , Michal Sroka , Dirk Fahland

In recent years, large language models have achieved breakthroughs on a wide range of benchmarks in natural language processing and continue to increase in performance. Recently, the advances of large language models have raised interest…

Computation and Language · Computer Science 2025-03-18 Jan Göpfert , Jann M. Weinand , Patrick Kuckertz , Detlef Stolten

Analogical reasoning, the transfer of relational structures across contexts (e.g., planet is to sun as electron is to nucleus), is fundamental to scientific discovery. Yet human insight is often constrained by domain expertise and…

Machine Learning · Computer Science 2025-10-28 Hongyu Guo

Discovering materials with desirable properties in an efficient way remains a significant problem in materials science. Many studies have tackled this problem by using different sets of information available about the materials. Among them,…

Materials Science · Physics 2025-03-04 Onur Boyar , Indra Priyadarsini , Seiji Takeda , Lisa Hamada

The field of catalysis holds paramount importance in shaping the trajectory of sustainable development, prompting intensive research efforts to leverage artificial intelligence (AI) in catalyst design. Presently, the fine-tuning of…

Machine Learning · Computer Science 2024-05-29 Ludi Wang , Xueqing Chen , Yi Du , Yuanchun Zhou , Yang Gao , Wenjuan Cui

Drug discovery projects entail cycles of design, synthesis, and testing that yield a series of chemically related small molecules whose properties, such as binding affinity to a given target protein, are progressively tailored to a…

Machine Learning · Computer Science 2020-02-10 Paul Maragakis , Hunter Nisonoff , Brian Cole , David E. Shaw

Chemical synthesis, as a foundational methodology in the creation of transformative molecules, exerts substantial influence across diverse sectors from life sciences to materials and energy. Current chemical synthesis practices emphasize…

Recent advances in large language models (LLMs) have unlocked novel opportunities for machine learning applications in the financial domain. These models have demonstrated remarkable capabilities in understanding context, processing vast…

General Finance · Quantitative Finance 2024-06-19 Yuqi Nie , Yaxuan Kong , Xiaowen Dong , John M. Mulvey , H. Vincent Poor , Qingsong Wen , Stefan Zohren