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Related papers: Language models in molecular discovery

200 papers

Recent breakthroughs in large language models (LLM) have stirred up global attention, and the research has been accelerating non-stop since then. Philosophers and psychologists have also been researching the structure of language for…

Computation and Language · Computer Science 2024-07-17 Joseph Chen

Large Language Models (LLMs) deliver powerful AI capabilities but face deployment challenges due to high resource costs and latency, whereas Small Language Models (SLMs) offer efficiency and deployability at the cost of reduced performance.…

Artificial Intelligence · Computer Science 2025-05-13 Yi Chen , JiaHao Zhao , HaoHao Han

Transformer-based large language models are rapidly advancing in the field of machine learning research, with applications spanning natural language, biology, chemistry, and computer programming. Extreme scaling and reinforcement learning…

Chemical Physics · Physics 2023-04-12 Daniil A. Boiko , Robert MacKnight , Gabe Gomes

In recent years, there has been remarkable progress in leveraging Language Models (LMs), encompassing Pre-trained Language Models (PLMs) and Large-scale Language Models (LLMs), within the domain of mathematics. This paper conducts a…

Computation and Language · Computer Science 2025-01-03 Wentao Liu , Hanglei Hu , Jie Zhou , Yuyang Ding , Junsong Li , Jiayi Zeng , Mengliang He , Qin Chen , Bo Jiang , Aimin Zhou , Liang He

The simplified molecular-input line-entry system (SMILES) is the most popular representation of chemical compounds. Therefore, many SMILES-based molecular property prediction models have been developed. In particular, transformer-based…

Quantitative Methods · Quantitative Biology 2022-05-03 Ingoo Lee , Hojung Nam

In the field of Artificial (General) Intelligence (AI), the several recent advancements in Natural language processing (NLP) activities relying on Large Language Models (LLMs) have come to encourage the adoption of LLMs as scientific models…

Computation and Language · Computer Science 2023-10-18 Evelina Leivada , Vittoria Dentella , Elliot Murphy

Considering the significance of proteins, computational protein science has always been a critical scientific field, dedicated to revealing knowledge and developing applications within the protein sequence-structure-function paradigm. In…

Computational Engineering, Finance, and Science · Computer Science 2025-01-28 Wenqi Fan , Yi Zhou , Shijie Wang , Yuyao Yan , Hui Liu , Qian Zhao , Le Song , Qing Li

Large Language Models (LLMs) are starting to be profiled as one of the most significant disruptions in the Software Testing field. Specifically, they have been successfully applied in software testing tasks such as generating test code, or…

Software Engineering · Computer Science 2025-09-30 Cristian Augusto , Antonia Bertolino , Guglielmo De Angelis , Francesca Lonetti , Jesús Morán

Scientific discovery increasingly depends on efficient experimental optimization to navigate vast design spaces under time and resource constraints. Traditional approaches often require extensive domain expertise and feature engineering.…

Machine Learning · Computer Science 2025-11-10 Bojana Ranković , Ryan-Rhys Griffiths , Philippe Schwaller

Artificial Intelligence (AI), especially AI agents, is increasingly being applied to chemistry, healthcare, and manufacturing to enhance productivity. In this review, we discuss the progress of AI and agentic AI in areas related to, and…

Language models (LMs) built upon deep neural networks (DNNs) have recently demonstrated breakthrough effectiveness in software engineering tasks such as code generation, completion, and repair. This has paved the way for the emergence of…

Software Engineering · Computer Science 2025-01-06 Jingzhi Gong , Vardan Voskanyan , Paul Brookes , Fan Wu , Wei Jie , Jie Xu , Rafail Giavrimis , Mike Basios , Leslie Kanthan , Zheng Wang

Scientific workflow systems are increasingly popular for expressing and executing complex data analysis pipelines over large datasets, as they offer reproducibility, dependability, and scalability of analyses by automatic parallelization on…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-07-09 Mario Sänger , Ninon De Mecquenem , Katarzyna Ewa Lewińska , Vasilis Bountris , Fabian Lehmann , Ulf Leser , Thomas Kosch

In recent years, the integration of large language models (LLMs) has revolutionized the field of robotics, enabling robots to communicate, understand, and reason with human-like proficiency. This paper explores the multifaceted impact of…

Robotics · Computer Science 2024-08-16 Yeseung Kim , Dohyun Kim , Jieun Choi , Jisang Park , Nayoung Oh , Daehyung Park

The paper looks at the role of large language models in academic knowledge creation based on a scoping review (2018 to January 2023) of how researchers have previously used the language model GPT to assist in the performance of academic…

Computation and Language · Computer Science 2023-03-14 Nigel Williams , Stanislav Ivanov , Dimitrios Buhalis

This paper introduces a system that integrates large language models (LLMs) into the clinical trial retrieval process, enhancing the effectiveness of matching patients with eligible trials while maintaining information privacy and allowing…

Information Retrieval · Computer Science 2024-11-01 Georgios Peikos , Pranav Kasela , Gabriella Pasi

Molecular dynamics (MD) is a powerful approach for modelling molecular systems, but it remains computationally intensive on spatial and time scales of many macromolecular systems of biological interest. To explore the opportunities offered…

Biomolecules · Quantitative Biology 2025-08-07 Mhd Hussein Murtada , Z. Faidon Brotzakis , Michele Vendruscolo

Crosswords are a form of word puzzle that require a solver to demonstrate a high degree of proficiency in natural language understanding, wordplay, reasoning, and world knowledge, along with adherence to character and length constraints. In…

Computation and Language · Computer Science 2025-06-10 Soumadeep Saha , Sutanoya Chakraborty , Saptarshi Saha , Utpal Garain

How can we compress language models without sacrificing accuracy? The number of compression algorithms for language models is rapidly growing to benefit from remarkable advances of recent language models without side effects due to the…

Computation and Language · Computer Science 2024-01-30 Seungcheol Park , Jaehyeon Choi , Sojin Lee , U Kang

Language models based on the Transformer architecture achieve excellent results in many language-related tasks, such as text classification or sentiment analysis. However, despite the architecture of these models being well-defined, little…

Computation and Language · Computer Science 2025-04-14 Miguel López-Otal , Jorge Gracia , Jordi Bernad , Carlos Bobed , Lucía Pitarch-Ballesteros , Emma Anglés-Herrero

Molecular property prediction is crucial for drug discovery and materials science, yet existing approaches suffer from limited interpretability, poor cross-task generalization, and lack of chemical reasoning capabilities. Traditional…

Machine Learning · Computer Science 2025-10-20 Jiaxi Zhuang , Yaorui Shi , Jue Hou , Yunong He , Mingwei Ye , Mingjun Xu , Yuming Su , Linfeng Zhang , Ying Qian , Linfeng Zhang , Guolin Ke , Hengxing Cai