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Abdominal Aortic Aneurysm (AAA) is an enlargement in the lower part of the main artery Aorta by 1.5 times its normal diameter. AAA can cause death if rupture occurs. Elective surgeries are recommended to prevent rupture based on geometrical…

Computational Engineering, Finance, and Science · Computer Science 2022-06-15 Farah Alkhatib , George C. Bourantas , Adam Wittek , Karol Miller

This study performs a large-eddy simulation of turbulent separated and reattached flow in an enlarged annular pipe. A vortex ring is periodically shed from the sudden expansion part. A longitudinal vortex occurs around the vortex ring,…

Fluid Dynamics · Physics 2022-06-22 Hideki Yanaoka , Naoto Yamada

This thesis is concerned with modeling and simulation of the mitral valve, one of the four valves in the human heart. The valve is composed of leaflets attached to a ring, the free edges of which are supported by a system of chordae, which…

Tissues and Organs · Quantitative Biology 2022-08-30 Alexander D. Kaiser

An abdominal aortic aneurysm (AAA) is a focal dilation of the aorta that, if not treated, tends to grow and may rupture. A significant unmet need in the assessment of AAA disease, for the diagnosis, prognosis and follow-up, is the…

Computer Vision and Pattern Recognition · Computer Science 2019-03-05 Karen López-Linares , Inmaculada García , Ainhoa García-Familiar , Iván Macía , Miguel A. González Ballester

Three-dimensional (3D) ultrasound imaging can overcome the limitations of conventional two dimensional (2D) ultrasound imaging in structural observation and measurement. However, conducting volumetric ultrasound imaging for large-sized…

Image and Video Processing · Electrical Eng. & Systems 2024-12-03 Caozhe Li , Enxiang Shen , Haoyang Wang , Yuxin Wang , Jie Yuan , Li Gong , Di Zhao , Weijing Zhang , Zhibin Jin

We study suspensions of oblate rigid particles in a viscous fluid for different values of the particle volume fractions. Direct numerical simulations have been performed using a direct-forcing immersed boundary method to account for the…

Fluid Dynamics · Physics 2021-02-23 M. Niazi Ardekani , P. Costa , W. -P. Breugem , F. Picano , L. Brandt

Coronary stent designs have undergone significant transformations in geometry, materials, and drug elution coatings, contributing to the continuous improvement of stenting success over recent decades. However, the increasing use of…

Medical Physics · Physics 2023-12-25 Ankush Kapoor , Nigel Jepson , Neil W. Bressloff , Poay Huan Loh , Tapabrata Ray , Susann Beier

Ultrasound (US) imaging is widely employed for diagnosis and staging of peripheral vascular diseases (PVD), mainly due to its high availability and the fact it does not emit radiation. However, high inter-operator variability and a lack of…

- Modeling Human cardiovascular system is always an important issue. One of the most effective methods is using lumped model to reach to a complete model of human cardiovascular system. Such modeling with advanced considerations is used in…

The zebrafish is a valuable model organism for studying cardiac development and diseases due to its many shared aspects of genetics and anatomy with humans and ease of experimental manipulations. Computational fluid-structure interaction…

Tissues and Organs · Quantitative Biology 2025-06-23 Alexander D. Kaiser , Jing Wang , Aaron L. Brown , Enbo Zhu , Tzung Hsiai , Alison L. Marsden

Purpose. It has been reported clinically that rupture or dissections in thoracic aortic aneurysms (TAA) often occur due to hypertension which may be modelled with sudden increase of peripheral resistance, inducing acute changes of blood…

Embolic stroke during cardiopulmonary bypass (CPB) is strongly influenced by cannula induced flow disturbances that govern emboli transport and aortic wall loading. This study quantifies how aortic cannula orientation affects embolic…

Medical Physics · Physics 2026-01-14 Nafis M. Arefin , Bryan C. Good

Coronary heart disease (CHD) remains a leading cause of mortality worldwide. This study introduces a novel approach that integrates patient-specific Multi-slice CT scans into CAD models, using a one-dimensional numerical framework to assess…

Medical Physics · Physics 2025-05-21 Priyanshu Ghosh , Sayan Karmakar , Disha Mondal , Oeshee Roy , Supratim Saha

This study aims to investigate the effect of various beam geometries and dimensions of input data on the sparse-sampling streak artifact correction task with U-Nets for clinical CT scans as a means of incorporating the volumetric context…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Tina Dorosti , Johannes Thalhammer , Sebastian Peterhansl , Daniela Pfeiffer , Franz Pfeiffer , Florian Schaff

Turbulent flow over a rounded broad-crested weir is investigated by means of detached eddy simulation (DES) and large eddy simulation (LES) with special emphasis on the interaction of coherent vortex structures with free-surface. In order…

Fluid Dynamics · Physics 2023-05-03 M. Anil Kizilaslan , Elif Deniz Atlas , Huseyin Yaban , Ender Demirel

The emergence of computational fluid dynamics (CFD) enabled the simulation of intricate transport processes, including flow in physiological structures, such as blood vessels. While these so-called hemodynamic simulations offer…

Direct numerical simulation of open-channel flow over a bed of spheres arranged in a regular pattern has been carried out at bulk Reynolds number and roughness Reynolds number (based on sphere diameter) of approximately 6900 and 120,…

Fluid Dynamics · Physics 2017-07-20 Marco Mazzuoli , Markus Uhlmann

Large-eddy simulation developments and validations are presented for an improved simulation of turbulent internal flows. Numerical methods are proposed according to two competing criteria: numerical qualities (precision and spectral…

Fluid Dynamics · Physics 2008-01-15 Jérôme Boudet , Joëlle Caro , L. Shao , Emmanuel Lévêque

The goal of this paper is to investigate the validity of a hybrid embedded/homogenized in-silico approach for modeling perfusion through solid tumors. The rationale behind this novel idea is that only the larger blood vessels have to be…

Computational Engineering, Finance, and Science · Computer Science 2021-07-15 Johannes Kremheller , Sebastian Brandstaeter , Bernhard A. Schrefler , Wolfgang A. Wall

In this article, the mechanics of drag reduction on an axisymmetric body of revolution by shallow dimples is presented by using the high-fidelity Reynolds Stress Modeling based simulations. Experimental results of drag evolution from…

Fluid Dynamics · Physics 2021-06-30 J P Panda , H V Warrior
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