Related papers: Simulation-Based Design of Bicuspidization of the …
Objective: Use of a vascular punch to produce circular heel and toe arteriotomies for femoral endarterectomy with patch angioplasty is a novel technique. This study investigated the plausibility of this approach and the mechanical…
Aortic shape analysis plays a key role in cardiovascular diagnostics, treatment planning, and understanding disease progression. We present a robust, fully automated pipeline for aortic shape analysis from cardiac MRI, combining deep…
Three-dimensional turbulence simulations of a RFX-mod diverted plasma are performed in the presence of a biasing electrode. The simulations show a strong suppression of turbulent transport caused by the induced $\mathbf{E}\times\mathbf{B}$…
The purpose of this work is to investigate the flow around a fixed NACA0012 airfoil profile at different angles of attack using wall-resolved LES. The profile has a chord length of c=0.1 m and is exposed to a flow at a Reynolds number of…
Developing an organoid computing platform from neurons in vitro demands stable, precisely controlled microenvironments. To address this requirement, we designed, simulated, and fabricated a microfluidic device featuring hexagonal wells…
Abdominal aortic aneurysms (AAA) pose a significant clinical risk due to their potential for rupture, which is often asymptomatic but can be fatal. Although maximum diameter is commonly used for risk assessment, diameter alone is…
In this study, we conduct a parametric analysis to evaluate the sensitivities of wall-modeled large-eddy simulation (LES) with respect to subgrid-scale (SGS) models, mesh resolution, wall boundary conditions and mesh anisotropy. While such…
It is known that the maximum diameter for the rupture-risk assessment of the abdominal aortic aneurysm is a generally good method, but not sufficient. Alternative features obtained with computational modeling may provide additional useful…
With tangent angle perturbation approach the axial symmetry deformation of a spherical vesicle in large under the pressure changes is studied by the elasticity theory of Helfrich spontaneous curvature model.Three main results in axial…
Stent intervention is a recommended therapy to reduce the pressure gradient and restore blood flow for patients with coarctation of the aorta (CoA). In this work, we developed a framework for personalized stent intervention in CoA using in…
Strokes are still one of the leading causes for death after heart diseases and cancer in all over the world. Most strokes happen because an artery that carries blood uphill from the heart to the head gets clogged. Most of the time, as with…
Cardiovascular surgeries and mechanical circulatory support devices create non-physiological blood flow conditions that can be detrimental, especially for pediatric patients. A source of complications is mechanical red blood cell (RBC)…
Experimental studies are carried out to investigate the effects of the geometrical parameters with a drag reducing spike on a hemispherical forebody in a supersonic freestream of $M_\infty=2.0$ at $0^{\circ}$ angle of attack. The spike…
The objective of this study is to develop a deep-learning based detection and diagnosis technique for carotid atherosclerosis using a portable freehand 3D ultrasound (US) imaging system. A total of 127 3D carotid artery scans were acquired…
The aortic valve is a three-leaflet passive structure that, driven by pressure differences between the left ventricle and the aorta, opens and closes during the heartbeat to ensure the correct stream direction and flow rate. In elderly…
This paper reports on the derivation and implementation of a shape optimization procedure for the minimization of hemolysis induction in biomedical devices. Hemolysis is a blood damaging phenomenon that may occur in mechanical…
Aneurysms are localized bulges of arteries, and they can rupture with fatal consequences. Complex mechanobiological factors preclude in vivo testing to assess the rupture risk of an aneurysm, and size based criteria are often used in…
Aims: To develop an in-silico model of the aorta and its spinal cord-supplying branches, and to characterise haemodynamic changes following aortic aneurysm (AA) repair with such a model. The work is motivated by the risk of spinal cord…
The outcome of vertebroplasty is hard to predict due to its dependence on complex factors like bone cement and marrow rheologies. Cement leakage could occur if the procedure is done incorrectly, potentially causing adverse complications. A…
In this study, finite element analysis is used to simulate the surgical deployment procedure of a bifurcated stent-graft on a real patient's arterial geometry. The stent-graft is modeled using realistic constitutive properties for both the…