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Imaging transparent samples remains an ongoing challenge in the study of unstained biological cells and material samples. Widely used methods trade off system complexity, cost and bulk, computational efficiency and information content. Here…

Phase and polarisation of coherent light are highly perturbed by interaction with microstructural changes in pre-malignant tissue, holding promise for label-free early cancer detection in endoscopically accessible tissues such as the…

Fluorescence microscopy is a powerful tool for imaging biological samples with molecular specificity. In contrast, phase microscopy provides label-free measurement of the sample's refractive index (RI), which is an intrinsic optical…

Optics · Physics 2022-01-26 Yi Xue , David Ren , Laura Waller

We introduce a single-frame diffractive imaging method called randomized probe imaging (RPI). In RPI, a sample is illuminated by a structured probe field containing speckles smaller than the sample's typical feature size. Quantitative…

In this paper we tackle the problem of recovering the phase of complex linear measurements when only magnitude information is available and we control the input. We are motivated by the recent development of dedicated optics-based hardware…

Machine Learning · Computer Science 2020-02-17 Sidharth Gupta , Rémi Gribonval , Laurent Daudet , Ivan Dokmanić

Entangled photons have the remarkable ability to be more sensitive to signal and less sensitive to noise than classical light. Joint photons can sample an object collectively, resulting in faster phase accumulation and higher spatial…

Optics · Physics 2015-09-04 Chien-Hung Lu , Matthew Reichert , Xiaohang Sun , Jason W. Fleischer

Optical phase estimation is a vital measurement primitive that is used to perform accurate measurements of various physical quantities like length, velocity and displacements. The precision of such measurements can be largely enhanced by…

Quantum correlation, such as entanglement and squeezing have shown to improve phase estimation in interferometric setups on one side, and non-interferometric imaging scheme of amplitude object on the other. In the last case, quantum…

Hyperspectral X-rays imaging holds promise for three-dimensional (3D) chemical analysis but remains limited in simultaneously capturing phase and absorption information due to complex setups and data burdens. We introduce quantitative X-ray…

Optics · Physics 2025-04-30 Herve Hugonne , KyeoReh Lee , Sugeun Jo , Jun Lim , YongKeun Park

Phase-contrast microscopy converts the optical phase introduced by transparent, unlabeled specimens into modulation in the intensity image. Modern phase imaging techniques are capable of quantifying phase shift at each point in the field of…

With the help of quantum entanglement, quantum dense metrology (QDM) is a technique that can perform the joint estimates of two conjugate quantities such as phase and amplitude modulations of an optical field with an accuracy beating the…

Quantum Physics · Physics 2022-02-02 Wei Du , J. F. Chen , Z. Y. Ou , Weiping Zhang

Quantum imaging with undetected light has recently emerged as a technique in which quantum correlations and nonlinear interferometry are combined to decouple illumination and detection paths. This approach has been more recently extended…

Objective: Quantitative technique based on In-line phase-contrast computed tomography with single scanning attracts more attention in application due to the flexibility of the implementation. However, the quantitative results usually suffer…

Medical Physics · Physics 2022-06-13 Suyu Liao , Shiwo Deng , Yining Zhu , Huitao Zhang , Peiping Zhu , Kai Zhang , Xing Zhao

Multi-spectral quantitative phase imaging (QPI) is an emerging imaging modality for wavelength dependent studies of several biological and industrial specimens. Simultaneous multi-spectral QPI is generally performed with color CCD cameras.…

Instrumentation and Detectors · Physics 2019-02-20 Azeem Ahmad , Anand Kumar , Vishesh Dubey , Ankit Butola , Balpreet Singh Ahluwalia , Dalip Singh Mehta

Quantitative MRI is highly desirable in terms of intrinsic tissue parameters such as T1, T2 and proton density. This approach promises to minimize diagnostic variability and differentiate normal and pathological tissues by comparing tissue…

Medical Physics · Physics 2018-06-21 Qing Lyu , Ge Wang

Infrared (IR) imaging is one of the significant tools for the quality control measurements of fabricated samples. Standard IR imaging techniques use direct measurements, where light sources and detectors operate at IR range. Due to the…

Quantum Physics · Physics 2020-09-01 Anna V. Paterova , Hongzhi Yang , Zi S. D. Toa , Leonid A. Krivitsky

Quasiparticle interference imaging (QPI) offers insight into the band structure of quantum materials from the Fourier transform of local density of states (LDOS) maps. Their acquisition with a scanning tunneling microscope is traditionally…

The visualization of pure phase objects by wavefront sensing has important applications ranging from surface profiling to biomedical microscopy, and generally requires bulky and complicated setups involving optical spatial filtering,…

Optics · Physics 2023-08-29 Jianing Liu , Hao Wang , Yuyu Li , Lei Tian , Roberto Paiella

Obstructions such as raindrops, fences, or dust degrade captured images, especially when mechanical cleaning is infeasible. Conventional solutions to obstructions rely on a bulky compound optics array or computational inpainting, which…

A direct measurement protocol allows reconstructing specific elements of the density matrix of a quantum state without using quantum state tomography. However, the direct measurement protocols to date are primarily based on weak or strong…

Quantum Physics · Physics 2021-10-13 Tianfeng Feng , Changliang Ren , Xiaoqi Zhou
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