Related papers: Associations Between Sleep Efficiency Variability …
Magnetoencephalographic (MEG) recordings from a large normative cohort (n = 619) were processed to extract measures of regional neuroelectric activity. The overall objective of the effort was to use these measures to identify normative…
Alzheimer's disease (AD) is a neurodegenerative disorder marked by memory loss and cognitive decline, making early detection vital for timely intervention. However, early diagnosis is challenging due to the heterogeneous presentation of…
Data harmonization is the process by which an equivalence is developed between two variables measuring a common trait. Our problem is motivated by dementia research in which multiple tests are used in practice to measure the same underlying…
The increasing prevalence of Autism Spectrum Disorder and Attention-Deficit/ Hyperactivity Disorder among students highlights the need to improve evaluation and diagnostic techniques, as well as effective tools to mitigate the negative…
Background. Alzheimer's disease and related dementia (ADRD) are characterized by multiple and progressive anatomo clinical changes. Yet, modeling changes over disease course from cohort data is challenging as the usual timescales are…
Attention Deficit/Hyperactivity Disorder (ADHD) is one of the most common neurodevelopmental disorders in children and is characterised by inattention, impulsiveness and hyperactivity. While several studies have analysed the static…
PD is linked to faster brain aging. Sex is recognized as an important factor in PD, such that males are twice as likely as females to have the disease and have more severe symptoms and a faster progression rate. Despite previous research,…
Motor dysfunction is a common sign of neurodegenerative diseases (NDs) such as Parkinson's disease (PD) and Alzheimer's disease (AD), but may be difficult to detect, especially in the early stages. In this work, we examine the behavior of a…
Early detection of Alzheimer's disease (AD) is crucial because its neurodegenerative effects are irreversible, and neuropathologic and social-behavioral risk factors accumulate years before diagnosis. Identifying higher-risk individuals…
Autism Spectrum Disorder (ASD) is characterized by an altered phenotype in social interaction and communication. Additionally, autism typically manifests differently in females as opposed to males: a phenomenon that has likely led to…
Accelerometry data has been widely used to measure activity and the circadian rhythm of individuals across the health sciences, in particular with people with advanced dementia. Modern accelerometers can record continuous observations on a…
Cognitive flexibility describes the human ability to switch between modes of mental function to achieve goals. Mental switching is accompanied by transient changes in brain activity, which must occur atop an anatomical architecture that…
Progressive cognitive decline spanning across decades is characteristic of Alzheimer's disease (AD). Various predictive models have been designed to realize its early onset and study the long-term trajectories of cognitive test scores…
This study investigates the causal relationships between Clinical Dementia Ratings (CDR) and its six domain scores across two distinct aging datasets: the Alzheimer's Disease Neuroimaging Initiative (ADNI) and the Longitudinal Aging Study…
Anatomical and functional brain studies have converged to the hypothesis that Autism Spectrum Disorders (ASD) are associated with atypical connectivity. Using a modified resting-state paradigm to drive subjects' attention, we provide…
Alzheimer's Disease and Related Dementias (AD/ADRD) are progressive neurodegenerative conditions that impair memory, thought processes, and functioning. Family caregivers of individuals with AD/ADRD face significant mental health challenges…
Cognition in midlife is an important predictor of age-related mental decline and statistical models that predict cognitive performance can be useful for predicting decline. However, existing models struggle to capture complex relationships…
Background: People with bipolar disorder (BD) tend to show widespread cognitive impairment compared to healthy controls. Impairments in processing speed (PS), attention, and executive function (EF) may represent 'core' impairments that have…
Driving is a complex daily activity indicating age and disease related cognitive declines. Therefore, deficits in driving performance compared with ones without mild cognitive impairment (MCI) can reflect changes in cognitive functioning.…
Identifying and utilising various biomarkers for tracking Alzheimer's disease (AD) progression have received many recent attentions and enable helping clinicians make the prompt decisions. Traditional progression models focus on extracting…