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Speech is usually used for constructing an automatic Alzheimer's dementia (AD) detection system, as the acoustic and linguistic abilities show a decline in people living with AD at the early stages. However, speech includes not only…

Audio and Speech Processing · Electrical Eng. & Systems 2024-10-11 Yilin Pan , Yanpei Shi , Yijia Zhang , Mingyu Lu

Cognitive impairment detection through spontaneous speech is a promising avenue for early diagnosis of Alzheimer's disease (AD) and mild cognitive impairment (MCI), where timely intervention can significantly improve patient outcomes. The…

Sound · Computer Science 2025-02-19 Yifan Gao , Long Guo , Hong Liu

Alzheimer's disease (AD) is the most common form of dementia, which causes problems with memory, thinking and behavior. Growing evidence has shown that the brain connectivity network experiences alterations for such a complex disease.…

Methodology · Statistics 2020-05-29 Chen Hao , Guo Ying , He Yong , Ji Jiadong , Liu Lei , Shi Yufeng , Wang Yikai , Yu Long , Zhang Xinsheng

In the complex realm of cognitive disorders, Alzheimer's disease (AD) and vascular dementia (VaD) are the two most prevalent dementia types, presenting entangled symptoms yet requiring distinct treatment approaches. The crux of effective…

Image and Video Processing · Electrical Eng. & Systems 2024-11-08 Salma Hassan , Dawlat Akaila , Maryam Arjemandi , Vijay Papineni , Mohammad Yaqub

The recent development of smartphone and wearable sensor technologies enable general public to carry self-tracking tasks more easily. Much work has been devoted to life data collection and visualisation to help people with better…

Computers and Society · Computer Science 2016-10-04 Li Guo

The speech auditory brainstem response (sABR) is an objective clinical tool to diagnose particular impairments along the auditory brainstem pathways. We explore the scaling behavior of the brainstem in response to synthetic /da/ stimuli…

Quantitative Methods · Quantitative Biology 2019-04-02 Marjan Mozaffarilegha , S. M. S. Movahed

Dementia is a complex syndrome impacting cognitive and emotional functions, with Alzheimer's disease being the most common form. This study focuses on enhancing dementia prediction using machine learning (ML) techniques on patient health…

Artificial Intelligence · Computer Science 2026-01-13 Shafiul Ajam Opee , Nafiz Fahad , Anik Sen , Rasel Ahmed , Fariha Jahan , Md. Kishor Morol , Md Rashedul Islam

This study examines how visual accessibility through cabinet design influences task performance, cognitive load, physical activity level, motivation, and user experience in a virtual kitchen among older adults with and without mild…

Human-Computer Interaction · Computer Science 2026-04-28 Ibrahim Bilau , Eunhwa Yang , Hyeokhyen Kwon , Stacie Smith , Bruce Walker , Hui Cai , Ece Erdogmus , Omobolanle Ogunseiju

Motivated behaviour relies on the brain's capacity to evaluate effort and reward. Dysregulation within these processes contributes to a spectrum of conditions, from hyperactivity in attention-deficit/hyperactivity disorder (ADHD) to…

Neurons and Cognition · Quantitative Biology 2026-04-20 Nam Trinh

The use of spontaneous language to derive appropriate digital markers has become an emergent, promising and non-intrusive method to diagnose and monitor dementia. Here we propose methods to capture language coherence as a cost-effective,…

Computation and Language · Computer Science 2023-10-17 Dimitris Gkoumas , Adam Tsakalidis , Maria Liakata

Objective Alzheimer disease (AD) is the most common cause of dementia, a syndrome characterized by cognitive impairment severe enough to interfere with activities of daily life. We aimed to conduct a systematic literature review (SLR) of…

Quantitative Methods · Quantitative Biology 2021-08-31 Sayantan Kumar , Inez Oh , Suzanne Schindler , Albert M Lai , Philip R O Payne , Aditi Gupta

Detection of subtle deficits in everyday functioning due to cognitive impairment is important for early detection of neurodegenerative diseases, particularly Alzheimer's disease. However, current standards for assessment of everyday…

Audio and Speech Processing · Electrical Eng. & Systems 2023-09-13 Yasunori Yamada , Kaoru Shinkawa , Masatomo Kobayashi , Miyuki Nemoto , Miho Ota , Kiyotaka Nemoto , Tetsuaki Arai

Research on modeling the distributional aspects in sensor-based digital health (sDHT) data has grown significantly in recent years. Most existing approaches focus on using individual-specific density or quantile functions. However, there…

Alzheimer's disease and related dementias(ADRD) affect nearly five million older adults in the United States, yet more than half remain undiagnosed. Speech-based natural language processing(NLP) offers a scalable approach for detecting…

We ask where, and under what conditions, dyslexic reading costs arise in a large-scale naturalistic reading dataset. Using eye-tracking aligned to word-level features (word length, frequency, and predictability), we model how each feature…

Computation and Language · Computer Science 2025-10-29 Hugo Rydel-Johnston , Alex Kafkas

Sleep is vital for maintaining cognitive function, facilitating metabolic waste removal, and supporting memory consolidation. However, modern societal demands, particularly shift work, often disrupt natural sleep patterns. This can induce…

Systems and Control · Electrical Eng. & Systems 2026-03-31 Zidi Tao , A. Agung Julius , John T Wen

Alterations in functional brain connectivity characterize neurodegenerative disorders such as Alzheimer's disease (AD) and frontotemporal dementia (FTD). As a non-invasive and cost-effective technique, electroencephalography (EEG) is…

Applications · Statistics 2025-11-19 Paolo Victor Redondo , Raphaël Huser , Hernando Ombao

MRI-based entorhinal cortical thickness (eCT) measurements predict cognitive decline in Alzheimer's disease (AD) with low cost and minimal invasiveness. Two prominent imaging paradigms, FreeSurfer (FS) and Advanced Normalization Tools…

Applications · Statistics 2022-04-08 Jesse W. Birchfield , Nicholas J. Tustison , Andrew J. Holbrook

Functional magnetic resonance imaging (fMRI) is essential for developing encoding models that identify functional changes in language-related brain areas of individuals with Neurocognitive Disorders (NCD). While large language model…

Neurons and Cognition · Quantitative Biology 2024-07-16 Yuejiao Wang , Xianmin Gong , Lingwei Meng , Xixin Wu , Helen Meng

Obstructive sleep apnea (OSA) is believed to contribute significantly to atrial fibrillation (AF) development in certain patients. Recent studies indicate a rising risk of AF with increasing OSA severity. However, the commonly used…

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