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Formal thought disorder (FTD), a hallmark of schizophrenia spectrum disorders, manifests as incoherent speech and poses challenges for clinical assessment. Traditional clinical rating scales, though validated, are resource-intensive and…

The average life expectancy is increasing globally due to advancements in medical technology, preventive health care, and a growing emphasis on gerontological health. Therefore, developing technologies that detect and track aging-associated…

Computational Engineering, Finance, and Science · Computer Science 2022-09-14 Saurav K. Aryal , Howard Prioleau , Legand Burge

Alzheimer's Disease (AD) is an irreversible neurodegenerative disease characterized by progressive cognitive decline as its main symptom. In the research field of deep learning-assisted diagnosis of AD, traditional convolutional neural…

Image and Video Processing · Electrical Eng. & Systems 2025-07-15 Yang Ming , Jiang Shi Zhong , Zhou Su Juan

Resting-state brain networks represent the intrinsic state of the brain during the majority of cognitive and sensorimotor tasks. However, no study has yet presented concise predictors of task-induced vigilance variability from…

Signal Processing · Electrical Eng. & Systems 2019-10-23 Mastaneh Torkamani-Azar , Sumeyra Demir Kanik , Serap Aydin , Mujdat Cetin

Background: Artificial intelligence (AI) models in healthcare depend on the fidelity of diagnostic data, yet the quality of such data is often compromised by variability in clinical documentation practices. In dementia, a condition already…

Learning and memory impairments are common characteristics of individuals with mild cognitive impairment (MCI) and mild Alzheimer's disease (miAD). Early diagnosis of MCI is necessary to prevent recurrence of the disease and developing of…

Neurons and Cognition · Quantitative Biology 2021-10-26 Mahmoud Kargar , Alireza Mohammadi

Background: While the relations between sleep, cognition and behavior have been extensively studied in adolescents and school-aged children, very little attention has been given to preschoolers. Objective: In this systematic review, our aim…

Neurons and Cognition · Quantitative Biology 2019-04-11 Eve Reynaud , Marie-Françoise Vecchierini , Barbara Heude , Marie-Aline Charles , Sabine Plancoulaine

Electroencephalography (EEG) has been widely used to study the relationship between naps and working memory, yet the effects of naps on distinct working memory tasks remain unclear. Here, participants performed word-pair and visuospatial…

Neurons and Cognition · Quantitative Biology 2023-11-16 Gi-Hwan Shin , Young-Seok Kweon , Heon-Gyu Kwak , Ha-Na Jo , Seong-Whan Lee

Accurate diagnosis of Alzheimer's Disease (AD) entails clinical evaluation of multiple cognition metrics and biomarkers. Metrics such as the Alzheimer's Disease Assessment Scale - Cognitive test (ADAS-cog) comprise multiple subscores that…

Machine Learning · Statistics 2017-08-16 Lev E. Givon , Laura J. Mariano , David O'Dowd , John M. Irvine , Abraham R. Schneider

Alzheimer disease (AD) is considered one of the leading causes of death in the United States, and there is no effective cure for it. Understanding the neuropathological mechanisms underlying AD is essential for identifying early, reliable…

This work shows that depression changes the correlation between features extracted from speech. Furthermore, it shows that using such an insight can improve the training speed and performance of depression detectors based on SVMs and LSTMs.…

Computation and Language · Computer Science 2023-07-10 Fuxiang Tao , Wei Ma , Xuri Ge , Anna Esposito , Alessandro Vinciarelli

We present two multimodal fusion-based deep learning models that consume ASR transcribed speech and acoustic data simultaneously to classify whether a speaker in a structured diagnostic task has Alzheimer's Disease and to what degree,…

Computation and Language · Computer Science 2021-07-01 Morteza Rohanian , Julian Hough , Matthew Purver

Early diagnosis of Alzheimer's disease (AD) is critical for intervention before irreversible neurodegeneration occurs. Structural MRI (sMRI) is widely used for AD diagnosis, but conventional deep learning approaches primarily rely on…

Image and Video Processing · Electrical Eng. & Systems 2025-03-04 Shijia Zhang , Xiyu Ding , Brian Caffo , Junyu Chen , Cindy Zhang , Hadi Kharrazi , Zheyu Wang

This study aims to identify a set of indicators to estimate cognitive workload using a multimodal sensing approach and machine learning. A set of three cognitive tests were conducted to induce cognitive workload in twelve participants at…

Neurons and Cognition · Quantitative Biology 2022-05-10 Niraj Hirachan , Anita Mathews , Julio Romero , Raul Fernandez Rojas

Background: Dementia, marked by cognitive decline, is a global health challenge. Alzheimer's disease (AD), the leading type, accounts for ~70% of cases. Electroencephalography (EEG) measures show promise in identifying AD risk, but…

Signal Processing · Electrical Eng. & Systems 2024-11-28 Veronica Henao Isaza , David Aguillon , Carlos Andres Tobon Quintero , Francisco Lopera , John Fredy Ochoa Gomez

This paper explores deterioration in Alzheimers Disease using Machine Learning. Subjects were split into two datasets based on baseline diagnosis (Cognitively Normal, Mild Cognitive Impairment), with outcome of deterioration at final visit…

Machine Learning · Computer Science 2023-06-21 Henry Musto , Daniel Stamate , Ida Pu , Daniel Stahl

Early diagnosis of Alzheimer's Disease (AD) is crucial for delaying its progression. While AI-based speech detection is non-invasive and cost-effective, it faces a critical data efficiency dilemma due to medical data scarcity and privacy…

Computation and Language · Computer Science 2026-02-17 Xiao Wei , Bin Wen , Yuqin Lin , Kai Li , Mingyang gu , Xiaobao Wang , Longbiao Wang , Jianwu Dang

Alzheimer's disease (AD) is a chronic neurodegenerative disease that causes memory loss and decline in cognitive abilities. AD is the sixth leading cause of death in the United States, affecting an estimated 5 million Americans. To assess…

Other Statistics · Statistics 2019-04-10 JinCheol Choi , Donghuan Lu , Mirza Faisal Beg , Jinko Graham , Brad McNeney

Dementia of Alzheimer's Type (DAT) is a complex disorder influenced by numerous factors, but it is unclear how each factor contributes to disease progression. An in-depth examination of these factors may yield an accurate estimate of…

Brain computer interfaces systems are controlled by users through neurophysiological input for a variety of applications including communication, environmental control, motor rehabilitation, and cognitive training. Although individuals with…

Human-Computer Interaction · Computer Science 2021-11-25 Deirdre McLaughlin , Daniel Klee , Tab Memmott , Betts Peters , Jack Wiedrick , Melanie Fried-Oken , Barry Oken