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Agitation is one of the most prevalent symptoms in people with dementia (PwD) that can place themselves and the caregiver's safety at risk. Developing objective agitation detection approaches is important to support health and safety of PwD…

Machine Learning · Computer Science 2023-08-16 Zhidong Meng , Andrea Iaboni , Bing Ye , Kristine Newman , Alex Mihailidis , Zhihong Deng , Shehroz S. Khan

Understanding of neuro-dynamics of a complex higher cognitive process, Working Memory (WM) is challenging. In WM, information processing occurs through four subsystems: phonological loop, visual sketch pad, memory buffer and central…

Signal Processing · Electrical Eng. & Systems 2020-03-13 Pankaj , Jamuna Rajeswaran , Divya Sadana

Brain networks from functional MRI have advanced our understanding of cortical activity and its disruption in neurodegenerative disorders. Recent work has increasingly focused on dynamic (time-varying) brain networks that capture both…

Neurons and Cognition · Quantitative Biology 2026-04-14 Nicolas Rubido , Venia Batziou , Marwan Fuad , Vesna Vuksanovic

Dementia is a progressive neurological disorder that profoundly affects the daily lives of older adults, impairing abilities such as verbal communication and cognitive function. Early diagnosis is essential for enhancing both lifespan and…

Computational Engineering, Finance, and Science · Computer Science 2023-11-07 Kaiying Lin , Peter Washington

Because of permanent use-dependent brain plasticity, all lifelong individuals' experiences are believed to influence the cognitive aging quality. In older individuals, both former and current musical practices have been associated with…

Driver's cognitive ability at a given moment is the most elusive variable in assessing driver's safety. In contrast to other physical conditions, such as short-sight, or manual disability cognitive ability is transient. Safety regulations…

Human-Computer Interaction · Computer Science 2022-04-26 Moti Salti , Yair Beery , Erez Aluf

Most brain disorders including Alzheimer's disease (AD) are related to alterations in the normal brain network organization and function. Exploring these network alterations using non-invasive and easy to use technique is a topic of great…

Neurons and Cognition · Quantitative Biology 2017-06-14 Aya Kabbara , Mahmoud Hassan , Mohamad Khalil , Wassim El Falou , Hassan Eid

Pre-symptomatic (or Preclinical) Alzheimer's Disease is defined by biomarker evidence of fibrillar amyloid beta pathology in the absence of clinical symptoms. Clinical trials in this early phase of disease are challenging due to the slow…

Applications · Statistics 2020-03-10 Dan Li , Samuel Iddi , Paul S. Aisen , Wesley K. Thompson , Michael C. Donohue

Alzheimer's disease is a progressive, neurodegenerative disorder that causes memory loss and cognitive decline. While there has been extensive research in applying deep learning models to Alzheimer's prediction tasks, these models remain…

Computer Vision and Pattern Recognition · Computer Science 2025-09-15 Emily Kaczmarek , Justin Szeto , Brennan Nichyporuk , Tal Arbel

Alzheimer s disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline, where early detection is essential for timely intervention and improved patient outcomes. Traditional diagnostic methods are…

The abnormal aggregation of extracellular amyloid-$\beta$ (A\beta) in senile plaques resulting in calcium (Ca^{+2}) dyshomeostasis is one of the primary symptoms of Alzheimer's disease (AD). Significant research efforts have been devoted in…

Neurons and Cognition · Quantitative Biology 2023-06-21 Hina Shaheen , Roderick Melnik , Sundeep Singh

Cognitive impairments in older adults represent a significant public health concern, necessitating accurate diagnostic and monitoring strategies. In this study, the principal cognitive and neuropsychological evaluations employed for the…

Neurons and Cognition · Quantitative Biology 2024-02-23 Chuang Li , Rubing Lin , Yantong Liu , Yichen Wei

Modern lifestyles contribute to insufficient sleep, impairing cognitive function and weakening the immune system. Sleep quality (SQ) is vital for physiological and mental health, making its understanding and accurate assessment critical.…

Human-Computer Interaction · Computer Science 2025-11-20 Gi-Hwan Shin

Although increasingly used for research, electronic health records (EHR) often lack gold-standard assessment of key data elements. Linking EHRs to other data sources with higher-quality measurements can improve statistical inference, but…

Methodology · Statistics 2025-03-05 Jenny Shen , Dane Isenberg , Kristin A. Linn , Rebecca A. Hubbard

Ageing impacts the brain's structural and functional organization and over time leads to various disorders, such as Alzheimer's disease and cognitive impairment. The process also impacts sensory function, bringing about a general slowing in…

Neurons and Cognition · Quantitative Biology 2022-09-07 L. J. Fosque , A. Alipour , M. Zare , R. V. Williams-Garcia , J. M. Beggs , G. Ortiz

Neighborhood disadvantage is associated with worse health and cognitive outcomes. Morphological similarity network (MSN) is a promising approach to elucidate cortical network patterns underlying complex cognitive functions. We hypothesized…

Cognitive fatigue has been a common problem among workers which has become an increasing global problem since the emergence of COVID-19 as a global pandemic. While existing multi-modal wearable sensors-aided automatic cognitive fatigue…

Signal Processing · Electrical Eng. & Systems 2021-05-07 Mohammad Arif Ul Alam

Since no effective therapies exist for Alzheimer's disease (AD), prevention has become more critical through lifestyle factor changes and interventions. Analyzing electronic health records (EHR) of patients with AD can help us better…

Computation and Language · Computer Science 2021-01-26 Zitao Shen , Yoonkwon Yi , Anusha Bompelli , Fang Yu , Yanshan Wang , Rui Zhang

Sleep stage classification is a common method used by experts to monitor the quantity and quality of sleep in humans, but it is a time-consuming and labour-intensive task with high inter- and intra-observer variability. Using Wavelets for…

Computer Vision and Pattern Recognition · Computer Science 2023-10-24 Eugenia Moris , Ignacio Larrabide

Electroencephalography (EEG)-based attention disorder research seeks to understand brain activity patterns associated with attention. Previous studies have mainly focused on identifying brain regions involved in cognitive processes or…

Neurons and Cognition · Quantitative Biology 2024-10-15 Debashis Das Chakladar , Foteini Simistira Liwicki , Rajkumar Saini