Related papers: Associations Between Sleep Efficiency Variability …

Timely implementation of interventions to slow cognitive decline among older adults requires accurate monitoring to detect changes in cognitive function. Data gathered using wearable devices that can continuously monitor factors known to be…

Measuring transient functional connectivity is an important challenge in Electroencephalogram (EEG) research. Here, the rich potential for insightful, discriminative information of brain activity offered by high temporal resolution is…

Background: Non-linear alterations in brain network connectivity may represent early neural signatures of Alzheimer's disease (AD) pathology in cognitively normal older adults. Understanding these changes and their cognitive relevance may…

Emerging evidence shows that cognitive deficits in Alzheimer disease (AD) are associated with disruptions in brain functional connectivity. Thus, the identification of alterations in AD functional networks has become a topic of increasing…

Sleep change is commonly reported in Alzheimer's disease (AD) patients and their brain wave studies show decrease in dreaming and non-dreaming stages. Although sleep disturbance is generally considered as a consequence of AD, it might also…

Objective While Alzheimer's disease (AD) and frontotemporal dementia (FTD) show some common memory deficits, these two disorders show partially overlapping complex spatiotemporal patterns of neural dynamics. The objective of this study is…

The goal of the present study is to identify autism using machine learning techniques and resting-state brain imaging data, leveraging the temporal variability of the functional connections (FC) as the only information. We estimated and…

Alzheimer's disease and related dementias (AD/ADRD) represent a growing healthcare crisis affecting over 6 million Americans. While genetic factors play a crucial role, emerging research reveals that social determinants of health (SDOH)…

The quality of sleep has a deep impact on people's physical and mental health. People with insufficient sleep are more likely to report physical and mental distress, activity limitation, anxiety, and pain. Moreover, in the past few years,…

Frailty is a geriatric syndrome associated with the lack of physiological reserve and consequent adverse outcomes (therapy complications and death) in older adults. Recent research has shown associations between heart rate (HR) dynamics (HR…

The 24-hour activity cycle (24HAC) is a new paradigm for studying activity behaviors in relation to health outcomes. This approach captures the interrelatedness of the daily time spent in physical activity (PA), sedentary behavior (SB), and…

For dementia screening and monitoring, standardized tests play a key role in clinical routine since they aim at minimizing subjectivity by measuring performance on a variety of cognitive tasks. In this paper, we report on a study that…

Human cognitive performance is an underlying factor in most of our daily lives, and numerous factors influence cognitive performance. In this work, we investigate how changes in sleep quality influence cognitive performance, measured from a…

Objectives: To examine sex differences in the associations between vascular risk factors and 6-year changes in the volume of white matter hyperintensities (WMH), and between changes in WMH volumes and changes in cognitive performance, in a…

Identifying preclinical biomarkers of neurodegenerative diseases remains a major challenge in aging research. In this study, we demonstrate that frequent "Don't know/can't remember" (DK) responses, often treated as missing data in…

Previous research has shown a clear relationship between sleep and memory, examining the impact of sleep deprivation on key cognitive processes over very short durations or in special populations. Here, we show, in a longitudinal 16 week…

Agitation is one of the most common responsive behaviors in people living with dementia, particularly among those residing in community settings without continuous clinical supervision. Timely prediction of agitation can enable early…

INTRODUCTION: Heterogeneity in the progression of Alzheimer's disease makes it challenging to predict the rate of cognitive and functional decline for individual patients. Tools for short-term prediction could help enrich clinical trial…

Sleep is among the most important factors affecting one's daily performance, well-being, and life quality. Nevertheless, it became possible to measure it in daily life in an unobtrusive manner with wearable devices. Rather than camera…

Background: Dementia, particularly Alzheimer's Disease (AD), is a progressive neurodegenerative disorder marked by cognitive decline. Early detection, especially at the Mild Cognitive Impairment (MCI) stage, is essential for timely…