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We present a new methodology for efficient and high-quality patterning of biological reagents for surface-based biological assays. The method relies on hydrodynamically confined nanoliter volumes of reagents to interact with the substrate…

Biomolecules · Quantitative Biology 2016-04-27 J. Autebert , J. F. Cors , David P. Taylor , G. V. Kaigala

Contact angle hysteresis of a macroscopic droplet on a heterogeneous but flat substrate is studied using the interface displacement model. First, the apparent contact angle of a droplet on a heterogeneous surface under the condition of…

Soft Condensed Matter · Physics 2007-05-23 Masao Iwamatsu

Hypothesis: Generating multi-layer cargo using conventional methods is challenging. We hypothesize that incorporating a Y-junction compound droplet generator to encase a target core inside a second liquid can circumvent the kinetic energy…

Fluid Dynamics · Physics 2024-08-20 Utsab Banerjee , Sirshendu Misra , Sushanta K. Mitra

In this study, capillary-driven flow of different pure liquids and diluted bitumen samples were studied using microfluidic channel (width of 30 um and depth of 9 um). Capillary filling kinetics of liquids as a function of time were…

Soft Condensed Matter · Physics 2016-12-01 Kiarash Keshmiri , Saeed Mozaffari , Plamen Tchoukov , Haibo Huang , Neda Nazemifard

We study microfluidic self digitization in Hele-Shaw cells using pancake droplets anchored to surface tension traps. We show that above a critical flow rate, large anchored droplets break up to form two daughter droplets, one of which…

Fluid Dynamics · Physics 2015-04-08 Gabriel Amselem , P. T. Brun , François Gallaire , Charles N. Baroud

We engineered a microfluidic platform to study the effects of bioactive glass nanoparticles (BGNs) on cell viability under static culture. We incorporated different concentrations of BGNs (1%, 2%, and 3% w/v) in collagen hydrogel (with a…

Tissues and Organs · Quantitative Biology 2024-08-07 Faezeh Ghobadi , Maryam Saadatmand , Sara Simorgh , Peiman Brouki Milan

Induction time, a measure of how long one will wait for nucleation to occur, is an important parameter in quantifying nucleation kinetics and its underlying mechanisms. Due to the stochastic nature of nucleation, efficient methods for…

Moisture-capturing hydrogels have emerged as attractive sorbent materials capable of converting ambient humidity into liquid water. Recent works have demonstrated exceptional water capture capabilities of hydrogels, while simultaneously,…

Soft Condensed Matter · Physics 2023-11-03 Gustav Graeber , Carlos D. Díaz-Marín , Leon C. Gaugler

In this article, we have developed a computational model to determine the droplet formation regime and its transition in a square microfluidic flow-focusing device that eventually dictate the droplet shape, size, and its formation…

Fluid Dynamics · Physics 2025-10-28 Somasekhara Goud Sontti , Arnab Atta

We demonstrate a novel technique for creating, manipulating, and combining femtoliter volume chemical containers. Possible uses include creating controlled chemical reactions involving small quantities of reagent, and studying the dynamics…

Biological Physics · Physics 2007-05-23 J. E. Reiner , A. M. Crawford , R. B. Kishore , Lori. S. Goldner , M. K. Gilson , K. Helmerson

Active droplets are artificial microswimmers built from a liquid dispersion by microfluidic tools and showing self-propelled motion. These systems hold particular interest for mimicking biological phenomena, such as some aspects of cell…

Soft Condensed Matter · Physics 2023-06-14 Adriano Tiribocchi , Mihir Durve , Marco Lauricella , Andrea Montessori , Davide Marenduzzo , Sauro Succi

Capillary condensation of water is ubiquitous in nature and technology. It routinely occurs in granular and porous media, can strongly alter such properties as adhesion, lubrication, friction and corrosion, and is important in many…

Mesoscale and Nanoscale Physics · Physics 2020-12-14 Qian Yang , P. Z. Sun , L. Fumagalli , Y. V. Stebunov , S. J. Haigh , Z. W. Zhou , I. V. Grigorieva , F. C. Wang , A. K. Geim

Precisely measuring pressure in microfluidic flows is essential for flow control, fluid characterization, and monitoring, but faces specific challenges such as \RE{achieving} sufficient resolution, non-invasiveness, or ease of use. Here, we…

The size distribution of aerosol droplets is a key parameter in a myriad of processes, and it is typically measured with optical aids (e.g., lasers or cameras) that require sophisticated calibration, thus making the measurement cost…

Fluid Dynamics · Physics 2025-10-23 Avshalom Offner

The simulation of hypersonic flows is computationally demanding due to large gradients of the flow variables caused by strong shock waves and thick boundary or shear layers. The resolution of those gradients imposes the use of extremely…

Computational Physics · Physics 2014-10-16 Sarah Frauholz , Arianna Bosco , Birgit U. Reinartz , Siegfried Müller , Marek Behr

Recent results from high-resolution solar granulation observations indicate the existence of a population of small granular cells that are smaller than 600 km in diameter. These small convective cells strongly contribute to the total area…

Solar and Stellar Astrophysics · Physics 2015-05-05 B. Lemmerer , D. Utz , A. Hanslmeier , A. Veronig , S. Thonhofer , H. Grimm-Strele , R. Kariyappa

We investigate experimentally the behavior of self-propelled water-in-oil droplets, confined in capillaries of different square and circular cross-sections. The droplet's activity comes from the formation of swollen micelles at its…

Soft Condensed Matter · Physics 2021-10-05 Charlotte de Blois , Vincent Bertin , Saori Suda , Masatoshi Ichikawa , Mathilde Reyssat , Olivier Dauchot

In order for a droplet to rebound rather than coalesce with a liquid bath, a layer of gas must persist throughout the impact. This gas, typically an air layer acts as a lubricant to the system and permits a pressure transfer between the two…

Fluid Dynamics · Physics 2025-06-18 Katie A Phillips , Radu Cimpeanu , Paul A Milewski

Hollow microgels are elastic polymer shells easily realizable in experiments. Recent works have shown the emergence of buckling events in dilute hollow microgels under the effect of an added osmotic pressure. Here, we perform large-scale…

Soft Condensed Matter · Physics 2026-01-19 Leah Rank , Emanuela Zaccarelli

The hydrodynamics of droplets is significant in wide-ranging applications involving immiscible fluids and emulsions in food and pharmaceutical. The control and manipulation of droplets are primarily a function of flow governing and…

Fluid Dynamics · Physics 2022-01-19 Akepogu Venkateshwarlu , Ram Prakash Bharti