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Mutations are typically classified by their effects on the nucleotide sequence and by their size. Here, we argue that if our main aim is to understand the effect of mutations on evolutionary outcomes (such as adaptation or speciation), we…

Other Quantitative Biology · Quantitative Biology 2020-09-30 Emma L. Berdan , Alexandre Blanckaert , Tanja Slotte , Alexander Suh , Anja M. Westram , Inês Fragata

We introduce a model of DNA sequence evolution which can account for biases in mutation rates that depend on the identity of the neighboring bases. An analytic solution for this class of non-equilibrium models is developed by adopting…

Biological Physics · Physics 2007-05-23 Peter F. Arndt , Christopher B. Burge , Terence Hwa

Although the role of lateral gene transfer is well recognized in the evolution of bacteria, it is generally assumed that it has had less influence among eukaryotes. To explore this hypothesis we compare the dynamics of genome evolution in…

Populations and Evolution · Quantitative Biology 2015-07-16 Gergely J. Szöllősi , Adrián Arellano Davín , Eric Tannier , Vincent Daubin , Bastien Boussau

We consider the evolution of populations under the joint action of mutation and differential reproduction, or selection. The population is modelled as a finite-type Markov branching process in continuous time, and the associated…

Populations and Evolution · Quantitative Biology 2009-02-23 Ellen Baake , Hans-Otto Georgii

Phylogenetic trees are simple models of evolutionary processes. They describe conditionally independent divergent evolution of taxa from common ancestors. Phylogenetic trees commonly do not have enough flexibility to adequately model all…

Populations and Evolution · Quantitative Biology 2025-11-11 Jonathan D. Mitchell , Barbara R. Holland

We study genetic networks that produce many species of non-coding RNA molecules that are present at a moderate density, as typically exists in the cell. The associations of the many species of these RNA are modeled physically, taking into…

Genomics · Quantitative Biology 2014-09-08 J. M. Deutsch

We introduce a model for the evolution of species triggered by generation of novel features and exhaustive combination with other available traits. Under the assumption that innovations are rare, we obtain a bursty branching process of…

Populations and Evolution · Quantitative Biology 2014-01-29 Stephanie Keller-Schmidt , Konstantin Klemm

The concept of neutral evolutionary networks being a significant factor in evolutionary dynamics was first proposed by Huynen {\em et al.} about 7 years ago. In one sense, the principle is easy to state -- because most mutations to an…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Russell K. Standish

Because human cognition is creative and socially situated, knowledge accumulates, diffuses, and gets applied in new contexts, generating cultural analogs of phenomena observed in population genetics such as adaptation and drift. It is…

Adaptation and Self-Organizing Systems · Physics 2013-08-26 Liane Gabora

The mutation process in evolution strategies has been interlinked with the normal distribution since its inception. Many lines of reasoning have been given for this strong dependency, ranging from maximum entropy arguments to the need for…

Neural and Evolutionary Computing · Computer Science 2025-04-11 Jacob de Nobel , Diederick Vermetten , Hao Wang , Anna V. Kononova , Günter Rudolph , Thomas Bäck

The evolutionary origins of structural features in reconstructed gene-regulatory networks (GRNs) remain poorly understood, especially given the random aspects of gene expression. Here, we extend a classical model of GRN evolution to allow a…

Populations and Evolution · Quantitative Biology 2026-04-30 Leonardo Ivan Estrella Dzib , James Holehouse

While Neutral Theory famously describes the number of discrete genetic differences in populations, we consider the number of genetic backgrounds under which such differences are observed - setting limits to the generalizability of their…

Populations and Evolution · Quantitative Biology 2023-03-21 Andre F. Ribeiro

The process of evolutionary diversification unfolds in a vast genotypic space of potential outcomes. During the past century there have been remarkable advances in the development of theory for this diversification, and the theory's success…

Populations and Evolution · Quantitative Biology 2011-10-14 Troy Day

Sex chromosomes have independently evolved in species with separate sexes in most lineages across the tree of life. However, the well-accepted canonical model of sex chromosome evolution is not universally supported. There is no single…

Populations and Evolution · Quantitative Biology 2024-08-23 Paris Veltsos , Sagar Shinde , Wen-Juan Ma

We study the evolution of the network properties of a populated network embedded in a genotype space characterised by either a low or a high number of potential links, with particular emphasis on the connectivity and clustering. Evolution…

Statistical Mechanics · Physics 2007-05-23 Paul Anderson , Henrik Jeldtoft Jensen

We propose a simple model for genetic adaptation to a changing environment, describing a fitness landscape characterized by two maxima. One is associated with "specialist" individuals that are adapted to the environment; this maximum moves…

Populations and Evolution · Quantitative Biology 2013-04-24 Andrea Baronchelli , Nick Chater , Morten H. Christiansen , Romualdo Pastor-Satorras

A fundamental issue discussed in evolutionary biology is the transition from unicellular to multicellular organisms. Here we develop non-robust models provided in [1] and attempt to get robust models investigated how differentiation of…

Populations and Evolution · Quantitative Biology 2015-12-15 Denis Tverskoy

The interaction between natural selection and random mutation is frequently debated in recent years. Does similar dilemma also exist in the evolution of real networks such as biological networks? In this paper, we try to discuss this issue…

Statistical Mechanics · Physics 2009-01-07 Zhen Shao , Hai-jun Zhou

Current-day genomes bear the mark of the evolutionary processes. One of the strongest indications is the sequence homology among families of proteins that perform similar biological functions in different species. The number of proteins in…

Biological Physics · Physics 2007-05-23 Joel S. Bader

There is surely some truth to the notion that culture evolves, but the Darwinian view of culture is trivial. Gabora does two things in this paper. First, she levels a reasoned and devastating attack on the adequacy of a Darwinian theory of…

Neurons and Cognition · Quantitative Biology 2015-06-23 Stuart Kauffman
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