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Transposable elements are DNA sequences that can move around to different positions in the genome. During this process, they can cause mutations, and lead to an increase in genome size. Despite representing a large genomic fraction,…

Cell Behavior · Quantitative Biology 2015-11-04 Alessandro Fontana

In a letter published in Molecular Biology Evolution [10], Chen and Zhang argue that the variation of the mutation rate along the Escherichia coli genome that we recently reported [3] cannot be evolutionarily optimised. To support this…

Genomics · Quantitative Biology 2013-05-09 Inigo Martincorena , Nicholas M. Luscombe

Understanding how genes influence phenotype across species is a fundamental challenge in genetic engineering, which will facilitate advances in various fields such as crop breeding, conservation biology, and personalized medicine. However,…

Machine Learning · Computer Science 2025-03-11 Mengdi Liu , Zhangyang Gao , Hong Chang , Stan Z. Li , Shiguang Shan , Xilin Chen

At any moment in time, evolution is faced with a formidable challenge: refining the already highly optimised design of biological species, a feat accomplished through all preceding generations. In such a scenario, the impact of random…

Populations and Evolution · Quantitative Biology 2024-02-20 Alessandro Fontana , Marios Kyriazis

It has been proposed that, since the origin of life and the ensuing evolution of biological species, a second evolutionary process has appeared on our planet. It is the evolution of culture-e.g., ideas, beliefs, and artifacts. Does culture…

Populations and Evolution · Quantitative Biology 2019-07-09 Liane Gabora , Diederik Aerts

Feedbacks between evolution and ecology are ubiquitous, with ecological interactions determining which mutants are successful, and these mutants in turn modifying community structure. We study the evolutionary dynamics of several ecological…

Populations and Evolution · Quantitative Biology 2024-11-27 Aditya Mahadevan , Daniel S. Fisher

The biological world, especially its majority microbial component, is strongly interacting and may be dominated by collective effects. In this review, we provide a brief introduction for statistical physicists of the way in which living…

Populations and Evolution · Quantitative Biology 2015-05-20 Nicholas Chia , Nigel Goldenfeld

It has been hypothesized that in the era just before the last universal common ancestor emerged, life on earth was fundamentally collective. Ancient life forms shared their genetic material freely through massive horizontal gene transfer…

Populations and Evolution · Quantitative Biology 2015-11-18 Hinrich Arnoldt , Steven H. Strogatz , Marc Timme

Neural codes appear efficient. Naturally, neuroscientists contend that an efficient process is responsible for generating efficient codes. They argue that natural selection is the efficient process that generates those codes. Although…

Neurons and Cognition · Quantitative Biology 2022-03-21 Han Kim

A central biological question is how natural organisms are so evolvable (capable of quickly adapting to new environments). A key driver of evolvability is the widespread modularity of biological networks--their organization as functional,…

Populations and Evolution · Quantitative Biology 2015-03-13 Jeff Clune , Jean-Baptiste Mouret , Hod Lipson

Evolving genomes increase a number of their genes by gene duplications. To escape degradation in a functionless pseudogene, any gene duplicate needs to be guarded by negative (purifying) selection from otherwise inevitable fixation of…

Populations and Evolution · Quantitative Biology 2007-05-23 Dmitri Parkhomchuk , Sergei Rodin

A central and long-standing issue in evolutionary theory is the origin of the biological variation upon which natural selection acts1. Some hypotheses suggest that evolutionary change represents an adaptation to the surrounding environment…

Statistical Mechanics · Physics 2007-05-23 J. Podani , Z. N. Oltvai , H. Jeong , B. Tombor , A. -L. Barabasi , E. Szathmary

Evolution of a universe with homogeneous extra dimensions is studied with the benefit of a well-chosen parameter space that provides a systematic, useful, and convenient way for analysis. In this model we find a natural evolution pattern…

Astrophysics · Physics 2009-11-10 Je-An Gu , W-Y. P. Hwang , Jr-Wei Tsai

Commonly recognized evolutionarily relevant effects of sexual reproduction include increased diversity, accelerated adaptation, and constrained accumulation of deleterious mutations, along with a secondary effect of species genotype…

Populations and Evolution · Quantitative Biology 2025-06-17 Assaf Marron , Smadar Szekely , Irun R. Cohen , David Harel

The Red Queen Hypothesis, which suggests that continual evolution can result from solely biotic interactions, has been studied in macroevolutionary and microevolutionary contexts. While the latter has been effective in describing examples…

Populations and Evolution · Quantitative Biology 2019-01-08 Meike T. Wortel , Han Peters , Nils Chr. Stenseth

Biological systems reach organizational complexity that far exceeds the complexity of any known inanimate objects. Biological entities undoubtedly obey the laws of quantum physics and statistical mechanics. However, is modern physics…

Other Quantitative Biology · Quantitative Biology 2018-02-26 Mikhail I. Katsnelson , Yuri I. Wolf , Eugene V. Koonin

The functioning of animal as well as human societies fundamentally relies on cooperation. Yet, defection is often favorable for the selfish individual, and social dilemmas arise. Selection by individuals' fitness, usually the basic driving…

Populations and Evolution · Quantitative Biology 2009-09-26 Jonas Cremer , Tobias Reichenbach , Erwin Frey

Apparent biodiversity on earth exists only if we compare different species separated from their environments. Meanwhile coexisting species have to be identical in terms of energetic interactions. Consider the biosphere as a network of…

Populations and Evolution · Quantitative Biology 2007-05-23 D. Balciunas

A natural example of evolution can be described by a time-dependent two degrees-of-freedom Hamiltonian. We choose the case where initially the Hamiltonian derives from a general cubic potential, the linearised system has frequencies 1 and…

Dynamical Systems · Mathematics 2021-11-03 Ferdinand Verhulst

The mechanisms underlying lifespan evolution in organisms have long been mysterious. However, recent studies have demonstrated that organisms evolutionarily gain noncoding RNAs (ncRNAs) that carry endogenous profound functions in higher…

Populations and Evolution · Quantitative Biology 2023-06-12 Anyou Wang
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