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This paper focuses on the maximum speed at which biological evolution can occur. I derive inequalities that limit the rate of evolutionary processes driven by natural selection, mutations, or genetic drift. These \emph{rate limits} link the…

Populations and Evolution · Quantitative Biology 2024-06-17 Luis Pedro García-Pintos

We study the probabilities of evolution based on random mutations and natural selection. We conclude that evolution to multicellular eukaryots, or even prokaryots, is unlikely to be the result of only random mutations. Complex organisms…

Populations and Evolution · Quantitative Biology 2007-05-23 B. Hoeneisen , G. Trueba

The premise of genetic analysis is that a causal link exists between phenotypic and allelic variation. Yet it has long been documented that mutant phenotypes are not a simple result of a single DNA lesion, but rather are due to interactions…

Genomics · Quantitative Biology 2014-06-04 Chris H. Chandler , Sudarshan Chari , Ian Dworkin

Meiotic recombination is a fundamental feature of sexually reproducing species. It is often required for proper chromosome segregation and plays important role in adaptation and the maintenance of genetic diversity. The molecular mechanisms…

Populations and Evolution · Quantitative Biology 2024-06-05 Susan E. Johnston

Evolution is the fundamental physical process that gives rise to biological phenomena. Yet it is widely treated as a subset of population genetics, and thus its scope is artificially limited. As a result, the key issues of how rapidly…

Populations and Evolution · Quantitative Biology 2017-08-23 Nigel Goldenfeld , Carl Woese

George Williams defined an evolutionary unit as hereditary information for which the selection bias between competing units dominates the informational decay caused by imperfect transmission. In this article, I extend Williams' approach to…

Populations and Evolution · Quantitative Biology 2012-01-17 Steven A. Frank

The theory of evolution by natural selection cannot be used to evaluate the truth value of the following proposition: Through evolution, there exists at least one species that can adapt to any one given environment. To address this issue,…

Biological Physics · Physics 2022-08-17 Kai Xu

Recent microbial experiments suggest that enhanced genetic drift at the frontier of a two-dimensional range expansion can cause genetic sectoring patterns with fractal domain boundaries. Here, we propose and analyze a simple model of…

Populations and Evolution · Quantitative Biology 2008-12-12 Oskar Hallatschek , David R. Nelson

Recent research has extended methods from the fields of thermodynamics and statistical mechanics into other disciplines. Most notably, one recent work creates a unified theoretical framework to understand evolutionary biology, machine…

Populations and Evolution · Quantitative Biology 2024-05-22 Daniel Sadasivan , Cole Cantu , Cecilia Marsh , Andrew Graham

The continuity of life and its evolution, we proposed, emerge from an interactive group process manifested in networks of interaction. We term this process \textit{survival-of-the-fitted}. Here, we reason that survival of the fitted results…

Neural and Evolutionary Computing · Computer Science 2025-06-17 Irun R. Cohen , Assaf Marron

We model evolution of plants in a world, made up of different locations, with multiple environments (mutually exclusive and collectively exhaustive subsets of locations). Each environment (landmass) has temperature, rainfall, and other…

Populations and Evolution · Quantitative Biology 2019-05-27 Alexander , Khazatsky , Albert Yu , Zihao Zhao , Gabe Zuckerman

The original hypothesis about Three-stage origin of life (TOL) on the Earth is developed and discussed. The role of the temperature factor in life origin is considered. It is supposed, that three stages of abiogenesis (DNA world, RNA world…

Other Quantitative Biology · Quantitative Biology 2012-01-04 Victor P. Novikov

The scientific community believes in the theory of evolution with a passion that rivals that of any religious belief. This passion extends beyond the irrefutable evidence of the fossil record to the familiar claims of survival of the…

Adaptation and Self-Organizing Systems · Physics 2007-05-23 Edward D. Weinberger

Search for possible relationships between phylogeny and ontogeny is one of the most important issues in the field of evolutionary developmental biology. By representing developmental dynamics of spatially located cells with gene expression…

Populations and Evolution · Quantitative Biology 2015-04-01 Takahiro Kohsokabe , Kunihiko Kaneko

Fundamental properties of macroscopic gene-mating dynamic evolutionary systems are investigated. We focus on a single locus, any number of alleles in a two-gender dioecious population, for a large class of systems within population…

Populations and Evolution · Quantitative Biology 2020-07-22 Juven Wang , Jiunn-Wei Chen

Darwin introduced the concept of the "living fossil" to describe species belonging to lineages that have experienced little evolutionary change, and suggested that species in more slowly evolving lineages are more prone to extinction (1).…

Genomics · Quantitative Biology 2013-02-12 Bianca Sclavi , John Herrick

A major goal of molecular evolutionary biology is to identify loci or regions of the genome under selection versus those evolving in a neutral manner. Correct identification allows accurate inference of the evolutionary process and thus…

Populations and Evolution · Quantitative Biology 2020-06-18 Fanny Pouyet , Kimberly J. Gilbert

Genetic drift is stochastic fluctuations of alleles frequencies in a population due to sampling effects. We consider a model of drift in an equilibrium population, with high mutation rates: few functional mutations per generation. Such…

Populations and Evolution · Quantitative Biology 2017-01-12 Alexey A. Shadrin , Dmitri V. Parkhomchuk

Darwinism conceives evolution as a consequence of random variation and natural selection, hence it is based on a materialistic, i.e. matter-based, view of science inspired by classical physics. But matter in itself is considered a very…

Biological Physics · Physics 2012-12-04 Diederik Aerts , Stan Bundervoet , Marek Czachor , Bart D'Hooghe , Liane Gabora , Philip Polk , Sandro Sozzo

Given a set of species whose evolution is represented by a species tree, a gene family is a group of genes having evolved from a single ancestral gene. A gene family evolves along the branches of a species tree through various mechanisms,…

Combinatorics · Mathematics 2019-05-14 Cedric Chauve , Yann Ponty , Michael Wallner