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Clinical diagnosis prediction models, when provided with a patient's medical history, aim to detect potential diseases early, facilitating timely intervention and improving prognostic outcomes. However, the inherent scarcity of patient data…

Computation and Language · Computer Science 2025-01-30 Mingyu Derek Ma , Xiaoxuan Wang , Yijia Xiao , Anthony Cuturrufo , Vijay S Nori , Eran Halperin , Wei Wang

Background: Natural Language Processing (NLP) is widely used to extract clinical insights from Electronic Health Records (EHRs). However, the lack of annotated data, automated tools, and other challenges hinder the full utilisation of NLP…

Computation and Language · Computer Science 2023-06-23 Elias Hossain , Rajib Rana , Niall Higgins , Jeffrey Soar , Prabal Datta Barua , Anthony R. Pisani , Ph. D , Kathryn Turner}

Objective: Provide guidance on sample size considerations for developing predictive models by empirically establishing the adequate sample size, which balances the competing objectives of improving model performance and reducing model…

Applications · Statistics 2024-07-25 Luis H. John , Jan A. Kors , Jenna M. Reps , Patrick B. Ryan , Peter R. Rijnbeek

Large language models (LLMs) have become increasingly popular in medical domains to assist physicians with a variety of clinical and operational tasks. Given the fast-paced and high-stakes environment of emergency departments (EDs), small…

Computation and Language · Computer Science 2025-10-07 Zirui Wang , Jiajun Wu , Braden Teitge , Jessalyn Holodinsky , Steve Drew

Large language models (LLMs) can generate or synthesize clinical text for a wide range of applications, from improving clinical documentation to augmenting clinical text analytics. Yet evaluations typically focus on a narrow aspect -- such…

Computation and Language · Computer Science 2026-05-19 Jinghui Liu , Sarvesh Soni , Anthony Nguyen

Having a sufficient quantity of quality data is a critical enabler of training effective machine learning models. Being able to effectively determine the adequacy of a dataset prior to training and evaluating a model's performance would be…

Machine Learning · Computer Science 2026-04-28 Arya Hatamian , Lionel Levine , Haniyeh Ehsani Oskouie , Majid Sarrafzadeh

In recent years, pretrained neural language models (PNLMs) have taken the field of natural language processing by storm, achieving new benchmarks and state-of-the-art performances. These models often rely heavily on annotated data, which…

Computation and Language · Computer Science 2023-02-06 Hoang Van

The development of a new diagnostic test ideally follows a sequence of stages which, amongst other aims, evaluate technical performance. This includes an analytical validity study, a diagnostic accuracy study and an interventional clinical…

Large Language Model (LLM) pre-training exhausts an ever growing compute budget, yet recent research has demonstrated that careful document selection enables comparable model quality with only a fraction of the FLOPs. Inspired by efforts…

Computation and Language · Computer Science 2024-06-10 Xiang Kong , Tom Gunter , Ruoming Pang

Clinicians spend a significant amount of time inputting free-form textual notes into Electronic Health Records (EHR) systems. Much of this documentation work is seen as a burden, reducing time spent with patients and contributing to…

Computation and Language · Computer Science 2018-08-09 Peter J. Liu

The accurate recognition of symptoms in clinical reports is significantly important in the fields of healthcare and biomedical natural language processing. These entities serve as essential building blocks for clinical information…

Computation and Language · Computer Science 2024-01-30 Mai A. Shaaban , Abbas Akkasi , Adnan Khan , Majid Komeili , Mohammad Yaqub

Machine learning-based multi-label medical text classifications can be used to enhance the understanding of the human body and aid the need for patient care. We present a broad study on clinical natural language processing techniques to…

Information Retrieval · Computer Science 2020-04-02 Vithya Yogarajan , Jacob Montiel , Tony Smith , Bernhard Pfahringer

Bibliometricians face several issues when drawing and analyzing samples of citation records for their research. Drawing samples that are too small may make it difficult or impossible for studies to achieve their goals, while drawing samples…

Applications · Statistics 2015-11-18 Richard Williams , Lutz Bornmann

Large language models show great potential in generating and optimizing code. Widely used sampling methods such as Nucleus Sampling increase the diversity of generation but often produce repeated samples for low temperatures and incoherent…

Machine Learning · Computer Science 2024-03-01 Dejan Grubisic , Chris Cummins , Volker Seeker , Hugh Leather

We investigate the effectiveness of fine-tuning large language models (LLMs) on small medical datasets for text classification and named entity recognition tasks. Using a German cardiology report dataset and the i2b2 Smoking Challenge…

Computation and Language · Computer Science 2025-03-28 Noah Losch , Lucas Plagwitz , Antonius Büscher , Julian Varghese

Medical professionals frequently work in a data constrained setting to provide insights across a unique demographic. A few medical observations, for instance, informs the diagnosis and treatment of a patient. This suggests a unique setting…

Computation and Language · Computer Science 2022-12-06 Pankaj Sharma , Imran Qureshi , Minh Tran

Medical events of interest, such as mortality, often happen at a low rate in electronic medical records, as most admitted patients survive. Training models with this imbalance rate (class density discrepancy) may lead to suboptimal…

Machine Learning · Computer Science 2022-08-02 Zepeng Huo , Xiaoning Qian , Shuai Huang , Zhangyang Wang , Bobak J. Mortazavi

Accurate clinical coding is essential for healthcare documentation, billing, and decision-making. While prior work shows that off-the-shelf LLMs struggle with this task, evaluations based on exact match metrics often overlook errors where…

Computation and Language · Computer Science 2025-10-10 Zhangdie Yuan , Han-Chin Shing , Mitch Strong , Chaitanya Shivade

Analyzing vast textual data and summarizing key information from electronic health records imposes a substantial burden on how clinicians allocate their time. Although large language models (LLMs) have shown promise in natural language…

We present DM-Bench, the first benchmark designed to evaluate large language model (LLM) performance across real-world decision-making tasks faced by individuals managing diabetes in their daily lives. Unlike prior health benchmarks that…

Machine Learning · Computer Science 2025-10-06 Maria Ana Cardei , Josephine Lamp , Mark Derdzinski , Karan Bhatia
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