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[Context and motivation] Large language models (LLMs) show notable results in natural language processing (NLP) tasks for requirements engineering (RE). However, their use is compromised by high computational cost, data sharing risks, and…

Software Engineering · Computer Science 2025-10-27 Mohammad Amin Zadenoori , Vincenzo De Martino , Jacek Dabrowski , Xavier Franch , Alessio Ferrari

Aims: To propose a general sample size framework for developing or updating a clinical prediction model using any statistical or machine learning method, based on drawing samples from anticipated posterior distributions and targeting…

Using Large Language Models (LLMs) to generate synthetic data for model training has become increasingly popular in recent years. While LLMs are capable of producing realistic training data, the effectiveness of data generation is…

Computation and Language · Computer Science 2024-07-23 Yinheng Li , Rogerio Bonatti , Sara Abdali , Justin Wagle , Kazuhito Koishida

While recent advancements in commercial large language models (LM) have shown promising results in medical tasks, their closed-source nature poses significant privacy and security concerns, hindering their widespread use in the medical…

Computation and Language · Computer Science 2024-07-02 Hyunjae Kim , Hyeon Hwang , Jiwoo Lee , Sihyeon Park , Dain Kim , Taewhoo Lee , Chanwoong Yoon , Jiwoong Sohn , Donghee Choi , Jaewoo Kang

The medical domain is often subject to information overload. The digitization of healthcare, constant updates to online medical repositories, and increasing availability of biomedical datasets make it challenging to effectively analyze the…

Machine Learning · Computer Science 2022-08-03 Ozan Ozyegen , Devika Kabe , Mucahit Cevik

Large Language Models (LLMs) have revolutionized various sectors, including healthcare where they are employed in diverse applications. Their utility is particularly significant in the context of rare diseases, where data scarcity,…

Computation and Language · Computer Science 2024-08-20 Qiuhao Lu , Rui Li , Andrew Wen , Jinlian Wang , Liwei Wang , Hongfang Liu

Advances in Large Language Models (LLMs) have led to significant interest in their potential to support human experts across a range of domains, including public health. In this work we present automated evaluations of LLMs for public…

Meta-analyses statistically aggregate the findings of different randomized controlled trials (RCTs) to assess treatment effectiveness. Because this yields robust estimates of treatment effectiveness, results from meta-analyses are…

Computation and Language · Computer Science 2024-07-26 Hye Sun Yun , David Pogrebitskiy , Iain J. Marshall , Byron C. Wallace

We present a conceptual model to measure disparity--the target study--where social groups may be similarly situated (i.e., balanced) on allowable covariates. Our model, based on a sampling design, does not intervene to assign social group…

Methodology · Statistics 2025-01-14 John W. Jackson , Yea-Jen Hsu , Raquel C. Greer , Romsai T. Boonyasai , Chanelle J. Howe

Existing approaches to sample size calculations for developing clinical prediction models have focused on ensuring that the expected value of a chosen performance measure meets a pre-specified target. For example, to limit…

Methodology · Statistics 2025-09-18 Menelaos Pavlou , Rumana Z. Omar , Gareth Ambler

In conventional supervised pattern recognition tasks, model selection is typically accomplished by minimizing the classification error rate on a set of so-called development data, subject to ground-truth labeling by human experts or some…

Machine Learning · Statistics 2011-08-25 Christopher M. White , Sanjeev P. Khudanpur , Patrick J. Wolfe

Background: Data collected in controlled settings typically results in high-quality datasets. However, in real-world applications, the quality of data collection is often compromised. It is well established that the quality of a dataset…

Computation and Language · Computer Science 2025-02-14 Tabinda Sarwar , Antonio Jose Jimeno Yepes , Lawrence Cavedon

Large language models (LLMs) are increasingly used to simulate survey responses, but synthetic data can be misaligned with the human population, leading to unreliable inference. We develop a general framework that converts LLM-simulated…

Methodology · Statistics 2026-05-21 Chengpiao Huang , Yuhang Wu , Kaizheng Wang

Instruction-tuning language models has become a crucial step in aligning them for general use. Typically, this process involves extensive training on large datasets, incurring high training costs. In this paper, we introduce a novel…

Computation and Language · Computer Science 2024-02-19 Dheeraj Mekala , Alex Nguyen , Jingbo Shang

There has been an influx of biomedical domain-specific language models, showing language models pre-trained on biomedical text perform better on biomedical domain benchmarks than those trained on general domain text corpora such as…

Computation and Language · Computer Science 2020-10-15 Hoo-Chang Shin , Yang Zhang , Evelina Bakhturina , Raul Puri , Mostofa Patwary , Mohammad Shoeybi , Raghav Mani

Recent foundational language models have shown state-of-the-art performance in many NLP tasks in zero- and few-shot settings. An advantage of these models over more standard approaches based on fine-tuning is the ability to understand…

Computation and Language · Computer Science 2024-04-16 Aleksandra Edwards , Jose Camacho-Collados

This paper achieves state of the art results for the ICD code prediction task using the MIMIC-III dataset. This was achieved through the use of Clinical BERT (Alsentzer et al., 2019). embeddings and text augmentation and label balancing to…

Computation and Language · Computer Science 2020-08-25 Brent Biseda , Gaurav Desai , Haifeng Lin , Anish Philip

Text-to-SQL generation enables non-experts to interact with databases via natural language. Recent advances rely on large closed-source models like GPT-4 that present challenges in accessibility, privacy, and latency. To address these…

Computation and Language · Computer Science 2025-02-18 Satya Krishna Gorti , Ilan Gofman , Zhaoyan Liu , Jiapeng Wu , Noël Vouitsis , Guangwei Yu , Jesse C. Cresswell , Rasa Hosseinzadeh

Data in the healthcare domain arise from a variety of sources and modalities, such as x-ray images, continuous measurements, and clinical notes. Medical practitioners integrate these diverse data types daily to make informed and accurate…

Machine Learning · Computer Science 2024-08-14 Liv Björkdahl , Oskar Pauli , Johan Östman , Chiara Ceccobello , Sara Lundell , Magnus Kjellberg

$\textbf{Objective}$ Develop an automatic diagnostic system which only uses textual admission information from Electronic Health Records (EHRs) and assist clinicians with a timely and statistically proved decision tool. The hope is that the…

Computation and Language · Computer Science 2017-12-08 Christy Li , Dimitris Konomis , Graham Neubig , Pengtao Xie , Carol Cheng , Eric Xing
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