Related papers: Research directions for kidney stone disease
Self-poisoning is a kinetic trap that can impair or prevent crystal growth in a wide variety of physical settings. Here we use dynamic mean-field theory and computer simulation to argue that poisoning is ubiquitous because its emergence…
In 2023, it is estimated that 81,800 kidney cancer cases will be newly diagnosed, and 14,890 people will die from this cancer in the United States. Preoperative dynamic contrast-enhanced abdominal computed tomography (CT) is often used for…
Kidney donations from living donors form an attractive alternative to long waiting times on a list for a post-mortem donation. However, even if a living donor for a given patient is found, the donor's kidney might not meet the patient's…
Medical image classification is a vital research area that utilizes advanced computational techniques to improve disease diagnosis and treatment planning. Deep learning models, especially Convolutional Neural Networks (CNNs), have…
Is cancer a disease that can be cured or a degenerative disease which comes predominantly with old age? We give an answer based on a two-dimensional representation of diseases. These two dimensions are defined as follows. In mortality…
Cancer progression involves the sequential accumulation of genetic alterations that cumulatively shape the tumour phenotype. In prostate cancer, tumours can follow divergent evolutionary trajectories that lead to distinct subtypes, but the…
We reconsider the commonly held assumption that warm debris disks are tracers of terrestrial planet formation. The high occurrence rate inferred for Earth-mass planets around mature solar-type stars based on exoplanet surveys (roughly 20%)…
Debris disks are the dust disks found around ~20% of nearby main sequence stars in far-IR surveys. They can be considered as descendants of protoplanetary disks or components of planetary systems, providing valuable information on…
Rheumatoid arthritis is a chronic autoimmune disease that is a major public health challenge. The disease is characterised by inflammation of synovial joints and cartilage erosion, which leads to chronic pain, poor life quality and, in some…
Cardiovascular disease and chronic kidney disease are major complications of diabetes, leading to high morbidity and mortality. Early detection of these conditions is critical, yet traditional diagnostic markers often lack sensitivity in…
Modeling disease progression through multiple stages is critical for clinical decision-making for chronic diseases, e.g., cancer, diabetes, chronic kidney diseases, and so on. Existing approaches often model the disease progression as a…
Autosomal polycystic kidney disease (ARPKD) is associated with progressive enlargement of the kidneys fuelled by the formation and expansion of fluid-filled cysts. The disease is congenital and children that do not succumb to it during the…
Incompatibility between patient and donor is a major barrier in kidney transplantation (KT). The increasing shortage of kidney donors has driven the development of desensitization techniques to overcome this immunological challenge.…
Twinkling Artifact is a valuable tool in detecting dense objects such as kidney stones, calculi etc., especially when there is no acoustic shadowing and presence of hyperechogenic tissues obstructs visualization. This phenomenon is not…
Multiple sclerosis (MS) is the most common disabling neurological disorders in the young adults. In spite of many researches, the cause of the disease has remained mainly not understood. All evidences indicate that environmental risk…
Cardiotoxicity induced by cancer treatment has become a major clinical concern, affecting the long-term survival and quality of life of cancer patients. Effective clinical decision-making, including the detection of cancer treatment-induced…
Over the past two decades, large strides have been made in the field of planet formation. Yet fundamental questions remain. Here we review our state of understanding of five fundamental bottlenecks in planet formation. These are: 1) the…
Modelling ultrasound speckle has generated considerable interest for its ability to characterize tissue properties. As speckle is dependent on the underlying tissue architecture, modelling it may aid in tasks like segmentation or disease…
The study of the last stages of planet formation, also known as debris disks, is fundamental to place constrains on the formation of planetary sized bodies. Debris disks are composed of dust and occasionally small amounts of gas, both…
Over the past 10 years abundant evidence has emerged that many (if not all) stars are born with circumstellar disks. Understanding the evolution of post-accretion disks can provide strong constraints on theories of planet formation and…