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Renal cancer is one of the most prevalent cancers worldwide. Clinical signs of kidney cancer include hematuria and low back discomfort, which are quite distressing to the patient. Some surgery-based renal cancer treatments like laparoscopic…
In clinical care, obtaining a correct diagnosis is the first step towards successful treatment and, ultimately, recovery. Depending on the complexity of the case, the diagnostic phase can be lengthy and ridden with errors and delays. Such…
Chronic kidney disease (CKD) affects millions worldwide and progresses irreversibly through stages culminating in end-stage renal disease (ESRD) and death. Outcome trials in CKD traditionally employ time-to-first-event analyses using the…
Purpose - Functional bowel diseases, including irritable bowel syndrome, chronic constipation, and chronic diarrhea, are some of the most common diseases seen in clinical practice. Many patients describe a range of triggers for altered…
Main sequence stars, like the Sun, are often found to be orbited by circumstellar material that can be categorized into two groups, planets and debris. The latter is made up of asteroids and comets, as well as the dust and gas derived from…
The precise diagnosis of urinary stones is crucial for devising effective treatment strategies. The diagnostic process, however, is often complicated by the low contrast between stones and surrounding tissues, as well as the variability in…
Melanoma is one of the most dangerous forms of cancer. The five-year survival rate is 98% if it is detected early. However, this rate plummets to 63% for regional disease and 17% when tumors have metastasized, that is, spread to distant…
The study of asteroids, its composition and trajectories, has been a persistent interest in the space exploration community. In addition, they are also perceived as a great threat to life on Earth, considering the possibility of an impact…
Background: Chronic kidney disease (CKD), a progressive disease with high morbidity and mortality, has become a significant global public health problem. Most existing models are static and fail to capture temporal trends in disease…
Patients associated with multiple co-occurring health conditions often face aggravated complications and less favorable outcomes. Co-occurring conditions are especially prevalent among individuals suffering from kidney disease, an…
Cell nuclei instance segmentation is a crucial task in digital kidney pathology. Traditional automatic segmentation methods often lack generalizability when applied to unseen datasets. Recently, the success of foundation models (FMs) has…
We present a systems-level analysis of end-stage kidney disease (ESKD) with a dynamical network analysis of 14 commonly measured blood-based biomarkers in patients undergoing regular haemodialysis. Utilizing a validated pipeline for…
Bone pain typically occurs immediately following skeletal damage with mechanical distortion or rupture of nociceptive fibres. The pain mechanism is also associated with chronic pain conditions where the healing process is impaired. Any load…
Despite efforts to increase the supply of organs from living donors, most kidney transplants performed in Australia still come from deceased donors. The age of these donated organs has increased substantially in recent decades as the rate…
As witnessed in the past year, where the world was brought to the ground by a pandemic, fighting Life-threatening diseases have found greater focus than ever. The first step in fighting a disease is to diagnose it at the right time.…
Cancers are caused by the accumulation of genetic alterations. Since this accumulation takes time, the incidence of most cancers is thought to increase exponentially with age. However, careful measurements of the age-specific incidence…
Many people are affected by diabetes around the world. This disease may have type 1 and 2. Diabetes brings with it several complications including diabetic retinopathy, which is a disease that if not treated correctly can lead to…
The sequence of visits and procedures performed by the patient in the health system, also known as the patient's pathway or trajectory, can reveal important information about the clinical treatment adopted and the health service provided.…
Our galaxy is full with planets. We now know that planets and planetary systems are diverse and come with different sizes, masses and compositions, as well as various orbital architectures. Although there has been great progress in…
Extensive photometric stellar surveys show that many main sequence stars show emission at infrared and longer wavelengths that is in excess of the stellar photosphere; this emission is thought to arise from circumstellar dust. The presence…