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Spontaneous phase separation, or demixing, is important in biological phenomena such as cell sorting. In particle-based models, an open question is whether differences in diffusivity can drive such demixing. While…

Soft Condensed Matter · Physics 2023-07-10 Erin McCarthy , Ojan Damavandi , Raj Kumar Manna , M. Lisa Manning

The aim of this paper is to discuss the mathematical modeling of Brownian active particle systems, a recently popular paradigmatic system for self-propelled particles. We present four microscopic models with different types of repulsive…

Statistical Mechanics · Physics 2022-05-31 M. Bruna , M. Burger , A. Esposito , S. M. Schulz

We introduce a system of active matter swarmalators composed of elastically interacting run-and-tumble active disks with an internal phase $\phi_i$. The disks experience an additional attractive or repulsive force with neighboring disks…

Soft Condensed Matter · Physics 2024-04-23 B. Adorjani , A. Libal , C. Reichhardt , C. J. O. Reichhardt

In contrast to equilibrium systems, inertia can profoundly impact the phase behavior of active systems. This has been made particularly evident in recent years, with motility-induced phase separation (MIPS) exhibiting several intriguing…

Soft Condensed Matter · Physics 2025-04-21 Jiechao Feng , Ahmad K. Omar

We computationally studied the phase behavior and dynamics of binary mixtures of active particles, where each 'species' had distinct activities leading to distinct velocities, fast and slow. We obtained phase diagrams demonstrating…

Soft Condensed Matter · Physics 2019-09-09 Thomas Kolb , Daphne Klotsa

Motility-induced phase separation (MIPS), the phenomenon in which purely repulsive active particles undergo a liquid-gas phase separation, is among the simplest and most widely studied examples of a nonequilibrium phase transition. Here, we…

Soft Condensed Matter · Physics 2021-05-11 Ahmad K. Omar , Katherine Klymko , Trevor GrandPre , Phillip L. Geissler

Motility-induced phase separation (MIPS) is a purely non-equilibrium phenomenon in which self-propelled particles phase separate without any attractive interactions. One surprising feature of MIPS is the emergence of polar, nematic, and…

Soft Condensed Matter · Physics 2022-02-08 Chiu Fan Lee

Active matter systems are inherently out of equilibrium and break the detailed balance (DB) at the microscopic scale, exhibiting vital collective phenomena such as motility-induced phase separation (MIPS). Here, we introduce a…

Soft Condensed Matter · Physics 2022-11-30 Jie Su , Zhiyu Cao , Jin Wang , Huijun Jiang , Zhonghuai Hou

Active soft matter frequently shows motility-induced phase separation (MIPS), where self-propelled particles condensate into clusters with an inner liquid-like structure. Such activity may also result in motility-induced crystallization…

Soft Condensed Matter · Physics 2026-02-24 Max Philipp Holl , Alina Barbar Steinberg , Uwe Thiele

We present a hydrodynamic theory for systems of dipolar active Brownian particles which, in the regime of weak dipolar coupling, predicts the onset of motility-induced phase separation (MIPS), consistent with Brownian dynamics (BD)…

Soft Condensed Matter · Physics 2022-03-29 Elena Sesé-Sansa , Guo-Jun Liao , Demian Levis , Ignacio Pagonabarraga , Sabine H. L. Klapp

One of the most notable features in repulsive particle based active matter systems is motility-induced-phase separation (MIPS) where a dense, often crystalline phase coexists with a low density fluid. In most active matter studies, the…

Soft Condensed Matter · Physics 2024-04-23 P. Forgacs , A. Libal , C. Reichhardt , N. Hengartner , C. J. O. Reichhardt

Collectives of actively-moving particles can spontaneously segregate into dilute and dense phases through a process known as motility-induced phase separation (MIPS). This captivating phenomenon is well-studied for randomly-moving particles…

Soft Condensed Matter · Physics 2026-03-04 Hongbo Zhao , Qiwei Yu , Andrej Košmrlj , Sujit S. Datta

Lattice models allow for a computationally efficient investigation of motility-induced phase separation (MIPS) compared to off-lattice systems. Simulations are less demanding and thus bigger systems can be accessed with higher accuracy and…

Statistical Mechanics · Physics 2021-01-26 Florian Dittrich , Thomas Speck , Peter Virnau

A combination of cellular contractility and active phase separation in cell-matrix composites is thought to be an enabler of spatiotemporal patterning in multicellular tissues across scales, from somitogenesis to cartilage condensation. To…

Soft Condensed Matter · Physics 2022-11-21 Sifan Yin , L Mahadevan

Cell deformability is an essential determinant for tissue-scale mechanical nature, such as fluidity and rigidity, and is thus crucial for understanding tissue homeostasis and stable developmental processes. However, numerical simulations…

Tissues and Organs · Quantitative Biology 2023-03-08 Nen Saito , Shuji Ishihara

Using a minimal model of active Brownian discs, we study the effect of a crucial parameter, namely the softness of the inter-particle repulsion, on motility-induced phase separation. We show that an increase in particle softness reduces the…

Soft Condensed Matter · Physics 2021-05-19 Monika Sanoria , Raghunath Chelakkot , Amitabha Nandi

Purely repulsive active particles spontaneously undergo motility-induced phase separation (MIPS) into condensed and dilute phases. Remarkably, the mechanical tension measured along the interface between these phases is negative. In…

Soft Condensed Matter · Physics 2018-10-31 Adam Patch , Daniel Sussman , David Yllanes , M. Cristina Marchetti

Motility-induced phase separation (MIPS) leads to cohesive active matter in the absence of cohesive forces. We present, extend and illustrate a recent generalized thermodynamic formalism which accounts for its binodal curve. Using this…

Statistical Mechanics · Physics 2018-10-11 Alexandre P. Solon , Joakim Stenhammar , Michael E. Cates , Yariv Kafri , Julien Tailleur

We examine motility-induced phase separation (MIPS) in two-dimensional run and tumble disk systems using both machine learning and noise fluctuation analysis. Our measures suggest that within the MIPS state there are several distinct…

Soft Condensed Matter · Physics 2024-04-23 D. McDermott , C. Reichhardt , C. J. O. Reichhardt

The motility-induced phase separation (MIPS) is the spontaneous aggregation of active particles, while equilibrium phase separation (EPS) is thermodynamically driven by attractive interactions between passive particles. Despite such…

Statistical Mechanics · Physics 2020-12-07 Kyosuke Adachi , Kyogo Kawaguchi