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We introduce a new rotationally invariant viewing angle classification method for identifying, among a large number of Cryo-EM projection images, similar views without prior knowledge of the molecule. Our rotationally invariant features are…

Biomolecules · Quantitative Biology 2014-03-19 Zhizhen Zhao , Amit Singer

Most of industrial robotic assembly tasks today require fixed initial conditions for successful assembly. These constraints induce high production costs and low adaptability to new tasks. In this work we aim towards flexible and adaptable…

Robotics · Computer Science 2019-03-26 Yuval Litvak , Armin Biess , Aharon Bar-Hillel

The cryo-electron microscope (cryo-EM) is increasingly popular these years. It helps to uncover the biological structures and functions of macromolecules. In this paper, we address image denoising problem in cryo-EM. Denoising the cryo-EM…

Computation · Statistics 2018-10-26 Yin Xian , Hanlin Gu , Wei Wang , Xuhui Huang , Yuan Yao , Yang Wang , Jian-Feng Cai

Background and Objective: The contrast of cryo-EM images varies from one to another, primarily due to the uneven thickness of the ice layer. This contrast variation can affect the quality of 2-D class averaging, 3-D ab-initio modeling, and…

Computer Vision and Pattern Recognition · Computer Science 2022-07-01 Yunpeng Shi , Amit Singer

Pose estimation is usually tackled as either a bin classification or a regression problem. In both cases, the idea is to directly predict the pose of an object. This is a non-trivial task due to appearance variations between similar poses…

Computer Vision and Pattern Recognition · Computer Science 2022-10-13 Georgios Kouros , Shubham Shrivastava , Cédric Picron , Sushruth Nagesh , Punarjay Chakravarty , Tinne Tuytelaars

3D human articulated pose recovery from monocular image sequences is very challenging due to the diverse appearances, viewpoints, occlusions, and also the human 3D pose is inherently ambiguous from the monocular imagery. It is thus critical…

Computer Vision and Pattern Recognition · Computer Science 2017-08-01 Mude Lin , Liang Lin , Xiaodan Liang , Keze Wang , Hui Cheng

Monocular 3D human pose estimation poses significant challenges due to the inherent depth ambiguities that arise during the reprojection process from 2D to 3D. Conventional approaches that rely on estimating an over-fit projection matrix…

Computer Vision and Pattern Recognition · Computer Science 2024-01-19 Junkun Jiang , Jie Chen

Cryo-Electron Tomography (cryo-ET) is a 3D imaging technology that enables the visualization of subcellular structures in situ at near-atomic resolution. Cellular cryo-ET images help in resolving the structures of macromolecules and…

Quantitative Methods · Quantitative Biology 2021-11-18 Hmrishav Bandyopadhyay , Zihao Deng , Leiting Ding , Sinuo Liu , Mostofa Rafid Uddin , Xiangrui Zeng , Sima Behpour , Min Xu

Single-particle electron cryomicroscopy is an essential tool for high-resolution 3D reconstruction of proteins and other biological macromolecules. An important challenge in cryo-EM is the reconstruction of non-rigid molecules with parts…

Image and Video Processing · Electrical Eng. & Systems 2021-05-31 Amit Moscovich , Amit Halevi , Joakim Andén , Amit Singer

Person re identification is a challenging retrieval task that requires matching a person's acquired image across non overlapping camera views. In this paper we propose an effective approach that incorporates both the fine and coarse pose…

Computer Vision and Pattern Recognition · Computer Science 2018-04-03 M. Saquib Sarfraz , Arne Schumann , Andreas Eberle , Rainer Stiefelhagen

Human pose estimation is a key step to action recognition. We propose a method of estimating 3D human poses from a single image, which works in conjunction with an existing 2D pose/joint detector. 3D pose estimation is challenging because…

Computer Vision and Pattern Recognition · Computer Science 2014-06-10 Chunyu Wang , Yizhou Wang , Zhouchen Lin , Alan L. Yuille , Wen Gao

We study clustered multitask learning in a semiparametric setting where tasks share a latent cluster structure in their target parameters but exhibit heterogeneous, potentially infinite-dimensional nuisance components. Such heterogeneity…

Machine Learning · Statistics 2026-05-05 Hanxiao Chen , Debarghya Mukherjee

3D pose estimation from a single 2D image is an important and challenging task in computer vision with applications in autonomous driving, robot manipulation and augmented reality. Since 3D pose is a continuous quantity, a natural…

Computer Vision and Pattern Recognition · Computer Science 2018-05-10 Siddharth Mahendran , Haider Ali , Rene Vidal

Dual-energy computed tomography (DECT) has shown great potential and promising applications in advanced imaging fields for its capabilities of material decomposition. However, image reconstructions and decompositions under sparse views…

Medical Physics · Physics 2016-08-01 Lei Li , Ailong Cai , Linyuan Wang , Bin Yan , Hanming Zhang , Zhizhong Zheng , Wenkun Zhang , Wanli Lu , Guoen Hu

Protein structure prediction models are now capable of generating accurate 3D structural hypotheses from sequence alone. However, they routinely fail to capture the conformational diversity of dynamic biomolecular complexes, often requiring…

Machine Learning · Computer Science 2025-12-02 Rishwanth Raghu , Axel Levy , Gordon Wetzstein , Ellen D. Zhong

Cryogenic electron microscopy (cryo-EM) provides images from different copies of the same biomolecule in arbitrary orientations. Here, we present an end-to-end unsupervised approach that learns individual particle orientations from cryo-EM…

Image and Video Processing · Electrical Eng. & Systems 2021-07-08 Youssef S. G. Nashed , Frederic Poitevin , Harshit Gupta , Geoffrey Woollard , Michael Kagan , Chuck Yoon , Daniel Ratner

Accurately estimating the pose of an object is a crucial task in computer vision and robotics. There are two main deep learning approaches for this: geometric representation regression and iterative refinement. However, these methods have…

Computer Vision and Pattern Recognition · Computer Science 2024-01-30 Jaewoo Park , Jaeguk Kim , Nam Ik Cho

Monocular 3D human-pose estimation from static images is a challenging problem, due to the curse of dimensionality and the ill-posed nature of lifting 2D-to-3D. In this paper, we propose a Deep Conditional Variational Autoencoder based…

Computer Vision and Pattern Recognition · Computer Science 2019-08-22 Saurabh Sharma , Pavan Teja Varigonda , Prashast Bindal , Abhishek Sharma , Arjun Jain

A video autoencoder is proposed for learning disentan- gled representations of 3D structure and camera pose from videos in a self-supervised manner. Relying on temporal continuity in videos, our work assumes that the 3D scene structure in…

Computer Vision and Pattern Recognition · Computer Science 2021-10-07 Zihang Lai , Sifei Liu , Alexei A. Efros , Xiaolong Wang

Motivation: Cellular Electron CryoTomography (CECT) is an emerging 3D imaging technique that visualizes subcellular organization of single cells at submolecular resolution and in near-native state. CECT captures large numbers of…

Quantitative Methods · Quantitative Biology 2018-05-16 Yixiu Zhao , Xiangrui Zeng , Qiang Guo , Min Xu
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